A5043891262- Healthcare Policy and Management
- Chronic Disease Management Strategies
- Drug Transport and Resistance Mechanisms
- Hospital Admissions and Outcomes
- Medical Device Sterilization and Disinfection
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Electronic Health Records Systems
- Aortic Disease and Treatment Approaches
- Geriatric Care and Nursing Homes
- Tissue Engineering and Regenerative Medicine
- Infection Control in Healthcare
- Emergency and Acute Care Studies
- Nursing Roles and Practices
- Enzyme Structure and Function
- Electrospun Nanofibers in Biomedical Applications
- HIV/AIDS drug development and treatment
- Pharmaceutical Practices and Patient Outcomes
- Clostridium difficile and Clostridium perfringens research
- Diabetes Management and Education
The University of Melbourne
2024
The Ohio State University Wexner Medical Center
2023
The Ohio State University
2022
Butler University
2021
Abstract Background Tissue-engineered vascular grafts (TEVGs) have the potential to advance surgical management of infants and children requiring congenital heart surgery by creating functional conduits with growth capacity. Methods Herein, we used an integrative computational-experimental approach elucidate natural history neovessel formation in a large animal preclinical model; combining vitro accelerated degradation study mechanical testing, implantation studies vivo imaging histology,...
Abstract Mycobacterium tuberculosis virulence is highly metal‐dependent with metal availability modulating the shift from dormant to active states of M. infection. Rv0045c a proposed metabolic serine hydrolase whose folded stability dependent on divalent concentration. Herein, we measured inhibition profile enzymatic activity and found specific transition cations (Cu 2+ ≥ Zn > Ni Co ) strongly inhibited its activity. The bind allosterically, largely affecting values for k cat rather than...
Introduction/AimDespite clear benefit from palliative care in end-stage chronic diseases, access is often limited, and rural largely undescribed. This study sought to determine if a approach provided people with disease their terminal hospital admission.MethodsMultisite, retrospective medical record audit, of decedents primary diagnosis lung, heart or renal failure, multimorbidity these conditions over 2019.ResultsOf 241 decedents, across five clinical sites, 143 (59.3%) were men, mean age...