A5083584693- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Cancer, Lipids, and Metabolism
- Eosinophilic Esophagitis
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- MRI in cancer diagnosis
- Health, psychology, and well-being
- Colorectal Cancer Screening and Detection
- Gastrointestinal motility and disorders
- Inflammatory mediators and NSAID effects
- Cardiac Imaging and Diagnostics
- Colorectal and Anal Carcinomas
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Systemic Sclerosis and Related Diseases
- Metastasis and carcinoma case studies
- Liver Disease and Transplantation
- Nutrition and Health in Aging
- Economic and Financial Impacts of Cancer
Michael E. DeBakey VA Medical Center
2014-2025
Baylor College of Medicine
2016-2025
Center for Innovation
2014-2025
VA Office of Research and Development
2024
Health Services Research & Development
2014
The effectiveness of surveillance endoscopy in patients with Barrett's oesophagus (BE) for reducing oesophageal adenocarcinoma (EAC)-related mortality BE is unclear.This a cohort study diagnosed the National Veterans Affairs hospitals during 2004-2009 excluding those conditions that affect overall survival. We identified EAC after diagnosis through 2011 and conducted chart reviews to identify programme, indication diagnosis, verify stage, therapy cause death. examined association between or...
Abstract Background H elicobacter pylori in the United States has been declining 1990s albeit less so among blacks and Hispanics. As socioeconomic status of racial groups evolved, it remains unclear whether prevalence or ethnic disparities . have changed. Methods This is a cross‐sectional study from Veteran Affairs center patients aged 40–80 years old who underwent esophagogastroduodenoscopy with gastric biopsies, which were cultured for irrespective findings on histopathology. Positive was...
The management of ultrashort (< 1cm) Barrett's esophagus (BE) remains unclear. We aimed to determine the prevalence BE (USBE) at index diagnosis, identify factors associated with persistent after USBE and risk dysplasia initial in a population United States veterans. This was retrospective cohort study Veterans Affairs hospital Houston, TX consecutive patients new diagnosis from 11/1990 6/2022 follow-up through 4/2023. Using pathology database, we identified any subsequent follow up EGD....
Esophageal adenocarcinoma is more common among non-Hispanic Whites (NHWs) than African Americans (AAs). It unclear whether its precursor, Barrett's esophagus (BE), also less AAs, and differences in risk factor profiles explain the racial disparity.Data were from a case-control study eligible Veterans Affairs patients scheduled for an upper endoscopy, sample identified primary care clinics. Participants completed questionnaire on sociodemographic clinical factors underwent...
Statins may reduce mortality from esophageal cancer by both reducing incidence but also improving prognosis. However, prior studies of statin use and have reported conflicting results.We identified 7882 patients with adenocarcinoma (EAC) 3868 squamous cell carcinoma (ESCC) the VA Central Cancer Registry diagnosed between 2002 2016. We prescriptions for statins that were filled before after diagnosis. Time-dependent Cox regression models used to calculate hazard ratios (HR) 95% CIs risk. a...
Endoscopic surveillance is recommended for patients with Barrett's esophagus (BE). However, it remains unclear if all BE benefit from long-term surveillance. We investigated the risk of esophageal adenocarcinoma (EAC) in relation to number successive endoscopies, years follow-up, and calendar year.We conducted a retrospective cohort study male veterans newly diagnosed during 2004-2009 follow-up until 30 September 2011. EAC was verified using detailed structured electronic medical records...
Few studies have examined the temporal trends of length in newly diagnosed Barrett's esophagus (BE) and arrived at conflicting results. The aim this study was to identify whether there has been a change over time BE diagnosis. This is retrospective, single-center, observational from Houston, Texas on between 2008 2013. All cases were defined by presence endoscopically visible histologic confirmation intestinalized columnar epithelium with goblet cells. measured using Prague classification....
Background Previous studies on Barrett’s esophagus (BE) risk factors have had differing case definitions and control groups. The purpose of this study was to examine differences in between newly diagnosed vs. prevalent BE, long- short-segment endoscopy-only BE without specialized intestinal metaplasia (SIM). Methods We conducted a cross-sectional among eligible patients scheduled for elective esophagogastroduodenoscopy (EGD) screening colonoscopy, recruited from primary care clinics at...
Gastric cancer remains one of the most common cancers globally. The pathogenesis intestinal-type gastric involves pre-malignant stages, including intestinal metaplasia (GIM), replacement native foveolar and/or glandular epithelium by epithelium. GIM prevalence is highly variable based on geography and race/ethnicity partly due to varying H. pylori, a potent risk factor. However, incidence does not mirror that demonstrating complex interaction between pylori factors. We will discuss...