Mrinalini Nair

ORCID: 0000-0002-4039-5460
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Research Areas
  • Bacterial Genetics and Biotechnology
  • Bacterial biofilms and quorum sensing
  • Brucella: diagnosis, epidemiology, treatment
  • Salmonella and Campylobacter epidemiology
  • Antimicrobial Resistance in Staphylococcus
  • Electrochemical sensors and biosensors
  • Microbial Fuel Cells and Bioremediation
  • Bacteriophages and microbial interactions
  • Escherichia coli research studies
  • Vibrio bacteria research studies
  • Amino Acid Enzymes and Metabolism
  • Enzyme Production and Characterization
  • Animal health and immunology
  • Animal Diversity and Health Studies
  • Peptidase Inhibition and Analysis
  • Pneumocystis jirovecii pneumonia detection and treatment
  • RNA and protein synthesis mechanisms
  • Aquaculture disease management and microbiota
  • Antibiotic Resistance in Bacteria
  • Burkholderia infections and melioidosis
  • Viral Infectious Diseases and Gene Expression in Insects
  • Medical Imaging and Pathology Studies
  • CRISPR and Genetic Engineering
  • Electrochemical Analysis and Applications
  • Enzyme Structure and Function

Maharaja Sayajirao University of Baroda
2005-2024

University of Sussex
1984

Abstract Pseudomonas aeruginosa is a highly invasive human pathogen in spite of the absence classical host specific virulence factors. Virulence factors regulated by quorum sensing (QS) P . cause acute infections to shift chronic diseases. Several small regulatory RNAs (sRNAs) mediate fine-tuning bacterial responses environmental signals and regulate sensing. In this study, we show that regulator RhlR positively influenced upon over expression Hfq dependent RNA PhrD transcripts starting from...

10.1038/s41598-018-36488-9 article EN cc-by Scientific Reports 2019-01-23

Brucella -specific nucleotide sequences encoding the BCSP 31 kDa protein, Omp2 and 16S rRNA were employed in three independent diagnostic PCR assays. Results of assays on six reference strains complete agreement. The results based bcsp omp2 19 Indian field isolates (human, bovine murine tissues) also agreed completely. However, when gene was as target PCR, only 14 out these 2 7 milk identified genus . blood samples insensitive to PCR. antibody-detecting ELISA ( n =87) from a serologically...

10.1099/jmm.0.47160-0 article EN Journal of Medical Microbiology 2007-09-24

To understand the genetic basis of high drug resistance in Shigella, 95 clinical isolates Shigella spp. (2001-2010) were obtained from Infectious Diseases Hospital, Kolkata, India. Ninety-three resistant to three or more antibiotics. Resistance nalidixic acid, trimethoprim, streptomycin, and co-trimoxazole was most common this population. Dendrogram analysis showed that S. sonnei strains clonally related when compared other species. The role mobile elements chromosome-borne factors analyzed...

10.2147/idr.s148726 article EN cc-by-nc Infection and Drug Resistance 2018-01-01

Pseudomonas aeruginosa (PA) is an electrogenic bacterium, in which extracellular electron transfer (EET) mediated by microbially-produced phenazines, especially pyocyanin. Increasing EET rate bacteria key for the development of biosensors and bioelectrofermentation processes. In this work, production pyocyanin Nicotinamide Adenine Dinucleotide (NAD) synthetase strain PA-A4 determined microbial fuel cells (MFCs). The MFC potentials correlates with NAD activity production. With fusion combined...

10.22541/au.170666543.31995021/v1 preprint EN Authorea (Authorea) 2024-01-31

Derepression of nitrogen fixation (nif) genes in Klebsiella pneumoniae following transfer from NH+ 4-sufficiency to N-free medium was preceded rapid expansion the guanosine 5′-di-phosphate 3′-diphosphate (ppGpp) pool. When derepressed supplemented with glutamine (600 μg ml−1), expression nifH and nifL promoters, determined as β-galactosidase activity nif: :lac merodiploid strains, stimulated 7-fold nitrogenase 26-fold; ppGpp did not accumulate, remaining at levels found 4-repressed...

10.1099/00221287-130-12-3063 article EN Microbiology 1984-12-01
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