A5079930659- Advanced Drug Delivery Systems
- Microplastics and Plastic Pollution
- Advancements in Transdermal Drug Delivery
- Proteins in Food Systems
- Bacterial biofilms and quorum sensing
- Phytochemicals and Antioxidant Activities
- Algal biology and biofuel production
- Advanced Fluorescence Microscopy Techniques
- Microencapsulation and Drying Processes
- Free Radicals and Antioxidants
- Wound Healing and Treatments
- Hydrogels: synthesis, properties, applications
- Marine Biology and Environmental Chemistry
- Pharmacological Effects of Natural Compounds
- Intramuscular injections and effects
- Genomics, phytochemicals, and oxidative stress
- Antimicrobial Peptides and Activities
- Mercury impact and mitigation studies
- Maritime and Coastal Archaeology
- Recycling and Waste Management Techniques
University of Palermo
2022-2024
An easy and viable crosslinking technology, based on the “click-chemistry” reaction copper(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition (click-crosslinking), was applied to graft copolymers of medium molecular weight (i.e., 270 kDa) hyaluronic acid (HA) grafted with ferulic (FA) residues bearing clickable propargyl groups, as well caffeic derivatives azido-terminated oligo(ethylene glycol) side chains. The obtained crosslinked materials were characterized from point view their...
The increasingly complex treatment of bacterial infections, and its relevance in the clinical setting, requires development innovative strategies to improve patients' quality life. In this context, polymeric microparticles represents a versatile drug delivery system (DDS) capable improving antibiotics' efficacy treatments, by loading drugs while modifying their release profile. study we aimed produce electrospraying using Poly-Butyl-Succinate (PBS), biodegradable biocompatible polyester....
In the present study, gastro-resistant microparticles (MPs) were produced using spray-drying technique as controlled-release systems for some model liposoluble vitamins, including retinyl-palmitate, retinyl-acetate, β-carotene, cholecalciferol and α-tocopherol. The gastroprotective action of three different excipients, anionic methacrylic copolymer (Eudraguard®® Biotic, E1207), cellulose acetate phthalate (CAP) whey proteins (WPs), was compared. latter used to produce a novel delivery system...
Abstract Background Inflammatory Bowel Disease (IBD) is a chronically relapsing inflammation of the gastrointestinal tract, with ambiguous etiology. Oral route most common and acceptable approach for drug administration in IBD treatment. However, it remains challenge to maintain stability drugs during oral treatment, particularly gastric environment, due its harsh conditions. In this context, antioxidant antiinflagmmatory properties various natural compounds, as Phycocyanin (PC),...
Microplastics (MPs), trace metals (TM) and metalloids (Ms) floating on the surface of seawater are a severe emerging issue global concern. Information about distribution these pollutants is often lacking, large-scale studies come with uncertainties because difficult comparisons results obtained using different methods to collect process data. This study presents comprehensive investigation MPs amount in during two transatlantic sampling campaigns, covering approximately 17,000 nautical miles...
The genus Brassica is an important source of food in the Mediterranean diet with documented nutritional and medicinal properties. However, few studies have investigated phytochemical composition biological activity wild Sicilian taxa. Thus, we aimed to study chemical profile antioxidant potential, vitro LPS-stimulated RAW 264.7 cells, a methanolic extract leaves macrocarpa Guss (B. macrocarpa) (Egadi Islands; Sicily-Italy). B. showed large amount glucosinolates different phenolic compounds....