A5065017078- Cancer-related molecular mechanisms research
- RNA Research and Splicing
- MicroRNA in disease regulation
- RNA modifications and cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- ATP Synthase and ATPases Research
- Circular RNAs in diseases
First Hospital of Jiaxing
2021
Chuxiong Normal University
2020
Abstract MAFG-AS1 is an oncogenic lncRNA in multiple types of cancer. However, its role bladder cancer (BC) remains unclear. The present study aimed to investigate the function BC. BC and paired non-tumor tissues were collected. Two cell lines HT01197 HT-1376 used. Dual luciferase activity assay, RT-qPCR, western blot, CCK-8, transwell invasion wound healing assay performed. We found that was significantly up-regulated predicted a poor survival rate. interacted with miR-125b-5p. expression...
Prostate cancer is the most common urinary malignancy in males. Long noncoding RNA small nucleolar host gene 1 (lncRNA SNHG1) has been reported to play a crucial role development of various cancers. However, understanding SNHG1 prostate still limited and needs further investigation. In this study, we found level was significantly upregulated tissues cells. Knockdown suppressed proliferation, migration invasion promoted cell apoptosis addition, knockdown downregulated proliferating nuclear...