Ali Azizi

ORCID: 0000-0002-4089-7735
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About
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • Immunotherapy and Immune Responses
  • HIV Research and Treatment
  • Natural product bioactivities and synthesis
  • Phytochemistry and Biological Activities
  • Immune Cell Function and Interaction
  • Phytochemicals and Antioxidant Activities
  • Genetic diversity and population structure
  • vaccines and immunoinformatics approaches
  • Plant biochemistry and biosynthesis
  • Plant Ecology and Taxonomy Studies
  • Animal Virus Infections Studies
  • Natural Antidiabetic Agents Studies
  • Light effects on plants
  • Hepatitis C virus research
  • Medicinal Plant Research
  • Drug-Induced Hepatotoxicity and Protection
  • SARS-CoV-2 and COVID-19 Research
  • Microbial infections and disease research
  • Hepatitis B Virus Studies
  • Plant Gene Expression Analysis
  • Viral gastroenteritis research and epidemiology
  • Chromosomal and Genetic Variations
  • Plant Pathogens and Fungal Diseases
  • Vibrio bacteria research studies

Bu-Ali Sina University
2012-2023

Sanofi (Canada)
2013-2017

University of Ottawa
2005-2016

Iran University of Medical Sciences
2016

Justus-Liebig-Universität Gießen
2008-2016

Hamedan University of Technology
2016

Children's Hospital of Eastern Ontario
2005-2011

Variation Biotechnologies (Canada)
2007-2010

University of Tehran
2002

Chemical-genetic profiling of inhibitory compounds can lead to identification their modes action. These profiles help elucidate the complex interactions between small bioactive and cell machinery, explain putative gene function(s).Colony size reduction was used investigate chemical-genetic profile cycloheximide, 3-amino-1,2,4-triazole, paromomycin, streptomycin neomycin in yeast Saccharomyces cerevisiae. target process protein biosynthesis. More than 70,000 strains were analyzed from array...

10.1186/1472-6769-10-6 article EN cc-by BMC Chemical Biology 2010-08-06

Abstract In total, 42 accessions of Origanum vulgare L., mostly originating from Europe, were evaluated, to detect molecular, quantitative morphological, and chemotype polymorphisms discover possible correlations between them. Twelve traits related morphological characteristics measured. The components in the essential oils identified by GC/MS analysis, oil contents 18 major compounds determined. A total 477 molecular including 214 AFLP (amplified fragment length polymorphism) 263 SAMPL...

10.1002/cbdv.201200125 article EN Chemistry & Biodiversity 2012-12-01

Hepatitis C virus (HCV) is a major cause of chronic hepatitis and hepatocellular carcinoma worldwide. The purpose this study was to determine how the HCV structural proteins affect dynamic functional properties hepatocytes measure extra-hepatic manifestations induced by these viral proteins. A transgenic mouse model established expressing core, E1 E2 downstream CMV promoter. RNA detected using RT-PCR in tissues, such as liver, kidney, spleen heart. Expression transgene analysed real-time PCR...

10.1099/vir.0.80969-0 article EN Journal of General Virology 2005-07-20

Zataria multiflora Boiss. is an aromatic shrub belonging to the Lamiaceae family. Its aerial parts are used in traditional medicine and pharmaceutical food industries. The terpenoid genetic profiles of 18 accessions Z. multiflora, collected different locations Iran, have been analyzed by GC/FID GC/MS or AFLP (amplified fragment length polymorphism) analyses, respectively. Altogether, 56 compounds were identified essential oils, with major constituents being thymol (6.0-54.9%), carvacrol...

10.1002/cbdv.201000070 article EN Chemistry & Biodiversity 2011-01-01

One of the major obstacles in design an effective vaccine against HIV-1 is its antigenic variation, which results viral escape from immune system. Through a bioinformatics approach, we developed innovative multivalent comprised pool 176 lipidated and nonlipidated peptides representing variable regions Env Gag proteins. The potency breadth candidate panel subtypes was evaluated nonhuman primate (cynomolgus macaques) humanized mouse (HLA-A2.1) models. demonstrate strong immunogenicity with...

10.4049/jimmunol.180.4.2174 article EN The Journal of Immunology 2008-02-15

Summary Introduction: Molecular markers are the examples of contribution genome technology to medicinal plant breeding through marker-assisted selection (MAS) for pharmaceutical quality. Objective: Forty-two accessions Origanum vulgare L. originating from Europe were evaluated detect genomic and chemotypic polymorphisms discover possible associations between them. Methods: A total 477 molecular including 214 AFLP (Amplified Fragment Length Polymorphism) 263 SAMPL (Selectively Amplified...

10.1515/hepo-2016-0010 article EN cc-by-nc-nd Herba Polonica 2016-06-01
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