- Lipoproteins and Cardiovascular Health
- Health Systems, Economic Evaluations, Quality of Life
- Obesity, Physical Activity, Diet
- Pharmaceutical Economics and Policy
- Child Nutrition and Feeding Issues
- Food Allergy and Anaphylaxis Research
- Infant Development and Preterm Care
- Dietetics, Nutrition, and Education
- Traffic and Road Safety
- Health Policy Implementation Science
- Transportation Planning and Optimization
- Pediatric health and respiratory diseases
- Eating Disorders and Behaviors
- Urban Transport and Accessibility
- Child Nutrition and Water Access
- Infant Health and Development
- Nutrition, Genetics, and Disease
- Behavioral Health and Interventions
NIHR Bristol Biomedical Research Centre
2018-2023
Nutricia (United Kingdom)
2022
University of Bristol
2018-2021
University Hospitals Bristol NHS Foundation Trust
2018-2021
National Institute for Health Research
2019-2021
Abstract Background Familial hypercholesterolaemia (FH) is a genetic condition characterised by elevated levels of low-density lipoprotein cholesterol (LDL-C) and an increased risk cardiovascular disease (CVD). Following dietary physical activity guidelines could help minimise this but adherence low. Interventions to target these behaviours are therefore required. A comprehensive understanding the behaviour change theory should drive process intervention development increase effectiveness...
Abstract Background Healthy gut microbiota is important for prognosis in cow's milk allergy (CMA). The application of synbiotics (specific pre‐ and probiotics) extensively hydrolyzed formulae (eHFs) a relatively new concept. Aims To evaluate synbiotic‐containing, whey‐based eHF (SeHF) with galacto‐oligosaccharides, fructo‐oligosaccharides, bifidobacterium breve M‐16V infants CMA. Materials Methods A 31‐day one‐arm pilot study 29 CMA (mean age 30.8 weeks [SD 11]) was undertaken, outcomes...
Objective Familial hypercholesterolaemia (FH) elevates low-density lipoprotein cholesterol (LDL-C) and increases cardiovascular disease (CVD) risk. This study aimed to provide evidence for the feasibility of conducting a randomised controlled trial evaluate efficacy an intervention designed improve diet physical activity in families with FH. Design A parallel, randomised, waitlist-controlled, pilot trial. Setting Three outpatient lipid clinics UK. Participants Families that comprised...
Abstract Background Untreated heterozygous familial hypercholesterolaemia (FH) causes high low-density lipoprotein cholesterol (LDL-C) levels and increased cardiovascular disease (CVD) risk. Despite pharmacological treatment, many treated individuals remain at higher CVD risk than non-affected individuals. This may be due to LDL-C targets not being met presence of other factors. Adhering dietary physical activity (PA) recommendations developed for with FH further reduce However, there is...