- Obesity, Physical Activity, Diet
- Adipose Tissue and Metabolism
- Regulation of Appetite and Obesity
- Physical Activity and Health
- Cardiovascular and exercise physiology
- Muscle metabolism and nutrition
- Eating Disorders and Behaviors
- Diet and metabolism studies
- Dietary Effects on Health
- Long-Term Effects of COVID-19
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Adipokines, Inflammation, and Metabolic Diseases
- Health and Lifestyle Studies
- Exercise and Physiological Responses
- COVID-19 and Mental Health
- Liver Disease Diagnosis and Treatment
- Fibroblast Growth Factor Research
- Sleep and related disorders
- Nutrition and Health in Aging
- Heart Rate Variability and Autonomic Control
- Sports Performance and Training
- Cardiovascular Disease and Adiposity
- Dialysis and Renal Disease Management
- Cardiovascular Function and Risk Factors
- Metabolism, Diabetes, and Cancer
Loughborough University
2016-2025
University Hospitals of Leicester NHS Trust
2019-2025
University of Leicester
2019-2025
NIHR Leicester Biomedical Research Centre
2017-2025
Waseda University
2022-2025
Chinese University of Hong Kong
2023-2025
National Health Service
2019-2025
Queen Elizabeth Hospital
2024
University Hospitals Birmingham NHS Foundation Trust
2024
National Institute for Health Research
2013-2023
Resistance (muscle strengthening) exercise is a key component of recommendations for weight control, yet very little known about the effects resistance on appetite. We investigated and aerobic hunger circulating levels gut hormones acylated ghrelin peptide YY (PYY). Eleven healthy male students: age 21.1 +/- 0.3 yr, body mass index 23.1 0.4 kg/m(2), maximum oxygen uptake 62.1 1.8 ml.kg(-1).min(-1) (means SE) undertook three, 8-h trials, 1) exercise: 90-min free lifting session followed by...
OBJECTIVE To determine whether breaking up prolonged sitting with short bouts of standing or walking improves postprandial markers cardiometabolic health in women at high risk type 2 diabetes. RESEARCH DESIGN AND METHODS Twenty-two overweight/obese, dysglycemic, postmenopausal (mean ± SD age 66.6 4.7 years) each participated two the following treatments: prolonged, unbroken (7.5 h) broken either a self-perceived light intensity (for 5 min every 30 min). Both allocation and treatment order...
Ghrelin is an orexigenic hormone secreted from endocrine cells in the stomach and other tissues. Acylation of ghrelin essential for appetite regulation. Vigorous exercise induces suppression, but this does not appear to be related suppressed concentrations total ghrelin. This study examined effect feeding on plasma acylated appetite. Nine male subjects aged 19-25 yr participated two, 9-h trials (exercise control) a random crossover design. Trials began at 0800 morning after overnight fast....
Acute energy deficits imposed by food restriction increase appetite and intake; however, these outcomes remain unchanged when are exercise. Our objective was to determine the potential role of acylated ghrelin peptide YY3–36 (PYY3–36) in mediating intake responses identical Twelve healthy males completed three 9-h trials (exercise deficit, control) a randomized counterbalanced design. Participants ran for 90 min (70% VO2 max) at beginning exercise deficit trial then rested 7.5 h. remained...
Acute exercise does not elicit compensatory changes in appetite parameters lean individuals; however, less is known about responses overweight individuals. This study compared the acute effects of moderate-intensity on appetite, energy intake and appetite-regulatory hormones overweight/obese Forty-seven healthy (n=22, 11 females; mean (s.d.) 37.5 (15.2) years; 22.4 (1.5) kg m−2) (n=25, 45.0 (12.4) years, 29.2 (2.9) individuals completed two, 8 h trials (exercise control). In trial,...
Abstract Hypertension is recognised as a leading attributable risk factor for cardiovascular disease and premature mortality. Global initiatives towards the prevention treatment of arterial hypertension are centred around non-pharmacological lifestyle modification. Exercise recommendations differ between professional scientific organisations, but generally unanimous on primary role traditional aerobic dynamic resistance exercise. In recent years, isometric exercise training (IET) has emerged...
Physical inactivity is recognised as a public health concern within children and interventions to increase physical activity are needed. The purpose of this research was evaluate the effect school-based healthy lifestyles intervention on activity, fruit vegetable consumption, body composition, knowledge, psychological variables. A non-randomised controlled study involving 8 primary schools (4 intervention, 4 control). Participants were 589 aged 7–11 years. lasted 10 months comprised CD-rom...
This study examined the effect of an acute bout brisk walking on appetite, energy intake, and appetite-stimulating hormone-acylated ghrelin.Fourteen healthy young males (age 21.9 +/- 0.5 yr, body mass index 23.4 0.6 kg x m(-2), (.)VO2max 55.9 1.8 mL kg(-1) min(-1); mean SEM) completed two 8-h trials (brisk control) in a randomized counterbalanced fashion. The trial commenced with 60 min subjectively paced level-motorized treadmill after which participants rested for 7 h. Participants...
Swimming may stimulate appetite and food intake but empirical data are lacking. This study examined appetite, intake, plasma acylated ghrelin responses to swimming. Fourteen healthy males completed a swimming trial control in random order. Sixty min after breakfast participants swam for 60 then rested six hours. Participants throughout the trial. During trials was measured at 30 intervals assessed periodically (0, 1, 2, 3, 4, 6, 7.5 h. ). Appetite suppressed during exercise before increasing...
The reason for high altitude anorexia is unclear but could involve alterations in the appetite hormones ghrelin and peptide YY (PYY). This study examined effect of resting exercising hypoxia (12.7% O(2); ∼4,000 m) on appetite, energy intake, plasma concentrations acylated PYY. Ten healthy males completed four, 7-h trials an environmental chamber a random order. four were control-normoxia, control-hypoxia, exercise-normoxia, exercise-hypoxia. During exercise trials, participants ran 60 min at...
High-intensity intermittent exercise induces physiological adaptations similar to energy-matched continuous exercise, but the comparative appetite and energy balance responses are unknown. Twelve healthy males (mean ± SD: age, 22 3 years; body mass index, 23.7 3.0 kg·m −2 ; maximum oxygen uptake, 52.4 7.1 mL·kg −1 ·min ) completed three 8 h trials (control, steady-state (SSE), high-intensity (HIIE)) separated by 1 week. Trials commenced upon completion of a standardized breakfast. Exercise...
To explore whether compensatory responses to acute energy deficits induced by exercise or diet differ sex.In experiment one, 12 healthy women completed three 9-h trials (control, exercise-induced (Ex-Def) and food restriction-induced deficit (Food-Def)) with identical being imposed in the Ex-Def (90-min run, ∼70% of V˙O2max) Food-Def trials. In two, 10 men two 7-h (control exercise). Sixty minutes running (∼70% was performed at beginning trial. The participants rested throughout remainder...