The excision repair cross-complementation group 1 (ERCC1) enzyme plays a rate-limiting role in the nucleotide pathway and is associated with resistance to platinum-based chemotherapy. purpose of this study was evaluate ERCC1 expression as predictive marker survival patients locally advanced squamous cell carcinoma head neck (SCCHN) treated cisplatin-based concurrent chemoradiotherapy (CCRT). assessed by immunohistochemical staining. median age 45 analysed 56 years (range 27-75 years), 82%...

Background: Recently, single-port video-assisted thoracic surgery (VATS) has been proposed as an alternative to the conventional three-port VATS for primary spontaneous pneumothorax (PSP).The aim of this study is evaluate early outcomes PSP.Methods: was performed PSP in 52 patients from March 2012 2013.We reviewed medical records these patients, retrospectively.Nineteen underwent (three-port group) and 33 (single-port group).Both groups were compared according operation time, number wedge...

Preservation of adequate vascular access is vital importance for patients undergoing chronic dialysis in renal failure. The aim this study to evaluate the successful rate and risk factors arteriovenous fistula (AVF) arm at a single center.Patients operation between January 2006 December 2011 were retrospectively identified.A total 362 operations performed. There 338 autologous AVFs (93.4%) 24 prosthetic grafts (6.6%). Men comprised 58.3% all subjects. Mean age was 59.5±14.7 years. 187...

1008 Background: Breast cancers comprise a heterogeneous group of tumors that are diverse in behavior and clinical outcome. Triple-negative (TN) breast defined as lack expression estrogen receptor (ER), progesterone (PgR), human epidermal growth factor 2 (HER2). TN have many similarities to BRCA1-associated cancers, which suggest dysfunction BRCA1 pathways might be related with sensitivity DNA damaging agents, such platinum compounds. Methods: We retrospectively analyzed the outcomes...

Aneurysm of the mitral valve, although uncommon, occurs most commonly in association with infective endocarditis aortic valve and true aneurysm is a rare cause regurgitation. We report case perforated posterior leaflet without concurrent initially mistaken diagnosis cystic mass, which was confirmed at operation successful annuloplasty.

The feasibility of single-port video-assisted thoracic surgery (SPVATS) for primary lung cancer is not well understood. In this study, we compared SP and multi-port (MP) VATS the surgical treatment patients with cancer.Surgical was performed in 181 at Inje University Haeundae Paik Hospital between June 2012 December 2015. A propensity-matched analysis used to compare postoperative outcomes evaluate comparative safety SPVATS MPVATS.There were 37 group 67 MPVATS group. Propensity matching...

Abstract Anomalous origin of the right coronary artery from left sinus is rare but potentially dangerous if any ischemic signs are present. Multiple therapeutic options were advocated so far. We experienced three different situations and surgical approaches to these anomalies, reviewed retrospectively. For first case, we made a neo-ostium on Valsalva anastomosed with after arteriotomy. second third cases, applied bypasses emergently: patient 2 gastroepiploic during off-pump bypass 3 internal...

Video-assisted thoracic surgery (VATS) is a minimally invasive technique that has many advantages in postoperative pain and recovery time. Because of its advantages, VATS one the surgical techniques widely used patients with lung cancer. Most surgeons perform for cancer three or more incisions. As evolved, single-port been attempted have reported. We describe our experiences single incision this report.

A primary giant cell tumor of the rib is very rare. The most common site a arising from posterior arc. anterior arc extremely treatment not well defined. Generally, complete surgical resection performed in patient with rib. We report case that was treated wide excision and chest wall reconstruction.

Surgical revascularization for patients with Buerger's disease is possible only in a few cases, due to the diffuse segmental involvement and lack of distal runoff vessels available bypass surgery. We encountered case resting pain right foot, coldness dysesthesia, cyanosis on 1st toe. The patient was treated an endovascular intervention after vein patch angioplasty failed inflammatory reaction disease. suggest that procedure can be effective treatment, even addition more conservative surgical...

Kimura disease (KD) is an immune-mediated chronic inflammatory of unknown etiology. KD has many complications associated with hypereosinophilia, including various forms allergic reactions and eosinophilic lung disease. Additionally, hypereosinophilia hypercoagulability, which may lead to thromboembolic events. A 36-year-old man presented acute limb ischemia coronary artery occlusion. He underwent thrombectomy, partial endarterectomy both popliteal arteries, stent insertion. a systemic that...

Abstract Despite marvelous advances in repair for acute type A aortic dissection over past decades, it remains challenging to the root when extended sinuses causes fragile because of its thinner layers, which are susceptible suture trauma. Here, we describe a modified Florida sleeve technique strengthen weakened root. After mobilization and coronary arteries, designed Dacron tube graft was wrapped outside as neo-adventitia reinforce dissected wall. During surgery dissection, our is easy...

To evaluate the outcomes of juxtarenal aortic occlusion (JRAO), a review 15 patients who underwent bypass replacement following aortorenal thrombectomy, especially focusing on safety suprarenal clamping or transient compression, was undertaken.During period June 2001 to November 2012, with JRAO (chronic 10, acute 5) were analyzed retrospectively. combined stenosis renal artery found in 2 patients, thrombus 8 and normal 5 patients.All males. Mean age 61.7±11.2 years. There 14 aortobifemoral...

Nowadays, infectious aortitis has become a rare disease thanks to antibiotics, but remains life-threatening.We present case of patient with acupuncture-induced leading aortic dissection.Chest computed-tomogram scan revealed Stanford type A dissection pericardial effusion.Under the impression an impending rupture, emergent surgery was performed.During surgery, identified incidentally, so she underwent resection infected aorta including surrounding tissues.Then ascending and hemi-arch were...

6036 Background: Type 1 insulin-like growth factor receptor (IGF-1R) plays an important role in the and apoptosis of cancer cell. The activities IGF-1R are modulated by a family high-affinity binding proteins (IGFBPs), which IGFBP-3 is major serum carrier protein. expression significance squamous cell carcinoma head neck (SCCHN) unknown. Methods: This study explored immunohistochemical tumor samples from 131 patients with surgically resected SCCHN. Results: positive was observed 96 (73.3%)...

In coronary artery bypass grafting, a diffusely diseased left anterior descending (LAD) is an obstacle to achieving complete revascularization, consequently leading the possibility of poor prognosis. Long segmental reconstruction with or without endarterectomy revascularization method for treating arteries. Herein, we report successful case long LAD using internal thoracic onlay patch after endarterectomy.

A 67-year-old woman presented with lower body edema and was found to have a suprarenal inferior vena cava (IVC) obstruction without hepatic vein partial anomalous pulmonary venous return (PAPVR) draining the right veins IVC below obstructed on CT angiography. The patient underwent retrohepatic cavoatrial bypass polytetrafluoroethylene (PTFE) 16-mm ringed graft via posterolateral thoracotomy retroperitoneal approach.

Background: Treatment for patent ductus arteriosus (PDA) in premature infants can consist of medical or surgical approaches.The appropriate therapeutic regimen remains contentious.This study evaluated the role surgery improving survival neonates weighing less than 1,500 g with PDA. Materials and Methods: From January 2008 to June 2011, 68 patients PDA were enrolled.The divided into three groups: a group managed only by treatment (group I), requiring after II), primary III).Results: The rate...

Mesenteric ischemic symptoms appear only when two of the three major splanchnic arteries from abdominal aorta are involved. Recently, we encountered a case chronic mesenteric ischemia in 50-year-old female patient caused by atherosclerotic obstruction celiac trunk and superior artery. She was treated with retrograde bypass graft right common iliac artery to (SMA) C-loop configuration. Complete revascularization is recommended for treatment intestinal ischemia. When not suitable recipient...

6061 Background: The cytotoxic effect of cisplatin is based on the DNA cross linking. Nucleotide excision repair associated with resistant to platinum-based chemotherapy. cross-complementation group 1 (ERCC1) enzyme plays a rate-limiting role in nucleotide pathway. We evaluated expression ERCC1 as predictive factor for survival patients squamous cell carcinoma head and neck (SCCHN) treated cisplatin-based concurrent chemoradiotherapy (CCRT). Methods: reviewed clinical records pathologic...