- Atomic and Subatomic Physics Research
- Advanced MRI Techniques and Applications
- Cystic Fibrosis Research Advances
- Respiratory viral infections research
- Ultrasound in Clinical Applications
- Multiple Myeloma Research and Treatments
- Medical Imaging Techniques and Applications
- MRI in cancer diagnosis
- Cardiac Arrhythmias and Treatments
- Congenital Diaphragmatic Hernia Studies
- Lung Cancer Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Medical Imaging and Pathology Studies
- Respiratory Support and Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neonatal Respiratory Health Research
- Cardiac Imaging and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Cancer Diagnosis and Treatment
- Bone and Joint Diseases
- Advanced Neuroimaging Techniques and Applications
- Biliary and Gastrointestinal Fistulas
- Neurofibromatosis and Schwannoma Cases
- Elbow and Forearm Trauma Treatment
- Shoulder Injury and Treatment
Humboldt-Universität zu Berlin
2023-2025
Charité - Universitätsmedizin Berlin
2023-2025
Freie Universität Berlin
2023-2025
Universitätsklinikum Würzburg
2019-2023
Society of Interventional Radiology
2020
European Neuroendocrine Tumor Society
2020
Siemens Healthcare (Germany)
2020
Ludwig-Maximilians-Universität München
2020
The Imaginary Signifier Get access Christian Metz Search for other works by this author on: Oxford Academic Google Scholar Screen, Volume 16, Issue 2, Summer 1975, Pages 14–76, https://doi.org/10.1093/screen/16.2.14 Published: 01 July 1975
Background In cystic fibrosis (CF), recurrent imaging and pulmonary function tests (PFTs) are needed for the assessment of lung during disease management. Purpose To assess clinical feasibility three-dimensional ultrashort echo time (UTE) MRI at breath holding quantitative image analysis ventilation inhomogeneity hyperinflation in CF compared with PFT. Materials Methods this prospective study from May 2018 to June 2019, participants healthy control underwent PFTs functional by using a...
Background The triple combination of the cystic fibrosis transmembrane regulator (CFTR) modulators elexacaftor, tezacaftor, and ivacaftor (hereafter, elexacaftor/tezacaftor/ivacaftor) has a positive effect on lung function in patients with (CF). Purpose To compare three-dimensional (3D) ultrashort echo time (UTE) MRI functional data to common parameters assessing CF undergoing elexacaftor/tezacaftor/ivacaftor therapy. Materials Methods In this prospective feasibility study, 16 participants...
Abstract Measurement of minimal residual disease (MRD) by next‐generation flow cytometry (NGF) is an important tool to define deep responses in multiple myeloma (MM). However, little known about the value combining NGF with functional imaging and its role for MRD‐based consolidation strategies clinical routine. In present study, we report our experience investigating these issues 102 patients newly diagnosed ( n = 57) relapsed/refractory MM 45). Imaging was performed using either positron...
Abstract Background Upper respiratory tract infections usually peak during winter months. Objective The purpose of this study was to evaluate whether imaging complicated upper airway infection in children increased the season 2022/2023. Materials and methods In a retrospective setting, pediatric magnetic resonance (MRI) computed tomography (CT) scans for evaluation performed between October 2022 April 2023 were analyzed regarding presence following complications: mastoiditis, abscess,...
Purpose: Ultrashort echotime (UTE) sequences aim to improve the signal yield in pulmonary magnetic resonance imaging (MRI). We demonstrate initial results of spiral 3-dimensional (3D) UTE-MRI for combined morphologic and functional pediatric patients. Methods: Seven patients with abnormalities were included this observational, prospective, single-center study, having following conditions: cystic fibrosis (CF) middle lobe atelectasis, CF allergic bronchopulmonary aspergillosis, primary...
To evaluate three-dimensional (3D) ultrashort echo time (UTE) MRI regarding image quality and suitability for functional analysis using gradient-echo sequences in breath-hold with self-navigation.In this prospective exploratory study, 10 patients (mean age, 21 years; age range, 5-58 five men) healthy control participants 25 10-39 underwent 3D UTE at 3.0 T. Imaging was performed a prototypical stack-of-spirals sequence during single breath holds (echo [TE], 0.05 msec) self-navigated "Koosh...
Abstract Background Functional lung MRI techniques are usually associated with time-consuming post-processing, where manual segmentation represents the most cumbersome part. The aim of this study was to investigate whether deep learning-based images which were scanned by a fast UTE sequence exploiting stack-of-spirals trajectory can provide sufficiently good accuracy for calculation functional parameters. Methods In study, acquired in 20 patients suffering from cystic fibrosis (CF) and 33...
This paper explores the combination of neural network quantization and entropy coding for memory footprint minimization. Edge deployment quantized models is hampered by harsh Pareto frontier accuracy-to-bitwidth tradeoff, causing dramatic accuracy loss below a certain bitwidth. can be alleviated thanks to mixed precision quantization, allowing more flexible bitwidth allocation. However, standard benefits remain limited due 1-bit frontier, that forces each parameter encoded on at least 1 bit...
ZUSAMMENFASSUNG Obwohl die Röntgenaufnahme des Thorax nach wie vor das bildgebende Standardverfahren in der pädiatrischen Lungendiagnostik ist, werden schnittbildgebenden Techniken für spezielle Fragestellungen auch im Kindes- und Jugendalter regelhaft benötigt. Durch beträchtliche technologische Fortschritte haben sich Möglichkeiten Lungenbildgebung mittels CT MRT deutlich erweitert. Wenngleich Strahlenexposition Untersuchungszeiten von CT-Untersuchungen drastisch gesenkt konnten, sind eine...
Hintergrund: Stürze zählen mit 49/100.000 Lebendgeborenen zu den häufigsten Gründen für Traumata in der Schwangerschaft. Eine Erweiterung des intersymphysären Spaltes über 10 mm wird als pathologisch angesehen. Die Symphysensprengung Schwangerschaft ist eine seltene und ätiologisch vielfältig bedingte Komplikation, die einer Inzidenz zwischen 1/300 bis 1/30.000 angegeben wird.
To evaluate the feasibility of non-contrast-enhanced three-dimensional ultrashort echo time (3D-UTE) MRI for pulmonary imaging in immunocompromised patients during hematopoietic stem cell transplantation (HSCT).MRI was performed using a stack-of-spirals 3D-UTE sequence (slice thickness: 2.34mm; matrix: 256 × 256; acquisition time: 12.7-17.6 seconds) enabling entire thorax within single breath-holds. Patients underwent before HSCT initiation, case periprocedural pneumonia, discharge, and...
Multipartite epicondyles may mimic fractures in the setting of pediatric elbow trauma. This study examines prevalence multipartite during skeletal development and their association with fractures.In this retrospective analysis, 4282 radiographs 1265 elbows 1210 patients aged 0-17 years were reviewed. The analyzed by two radiologists consensus reading, number visible portions medial lateral was noted. For which epicondylar ossification not yet visible, already fused humerus or could be...
Ultrashort-echo-time (UTE) sequences have been developed to overcome technical limitations of pulmonary magnetic resonance imaging (MRI). Recently, it has shown that UTE with breath-hold allow rapid image acquisition sufficient quality. However, patients impaired respiration require alternative strategies while breathing freely.To compare the diagnostic performance free-breathing three-dimensional (3D)-UTE different trajectories based on immunocompromised patients.In a prospective study...
Single breath-hold 3D-UTE-MRI was proposed for simultaneous evaluation of lung morphology and function. Sixteen patients with cystic fibrosis (CF) underwent initial follow-up in 2019 2021. In line a previous study, referenced voxelwise fractional ventilation (FV) provided marker that correlates strongly the clearance index (LCI), reflecting inhomogeneity. Seven received new drug-combination (ivacaftor/elexacaftor/tezacaftor) significantly improved function during clinical follow-up....
Hintergrund Typischerweise kommt es während der Wintermonate zu einem Anstieg oberer Atemwegsinfektionen.