C Simionescu

ORCID: 0000-0002-4127-7490
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About
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Research Areas
  • Ocular Oncology and Treatments
  • Prenatal Screening and Diagnostics
  • Ovarian cancer diagnosis and treatment
  • Congenital Heart Disease Studies
  • Cancer and Skin Lesions
  • Nonmelanoma Skin Cancer Studies
  • Wnt/β-catenin signaling in development and cancer
  • Endometrial and Cervical Cancer Treatments
  • Salivary Gland Tumors Diagnosis and Treatment
  • Fetal and Pediatric Neurological Disorders
  • Cardiovascular Issues in Pregnancy
  • Cancer Cells and Metastasis
  • Sarcoma Diagnosis and Treatment
  • Breast Lesions and Carcinomas
  • Oral and Maxillofacial Pathology
  • Hydraulic and Pneumatic Systems
  • Cancer, Lipids, and Metabolism
  • Natural Fiber Reinforced Composites
  • Parvovirus B19 Infection Studies
  • Hedgehog Signaling Pathway Studies
  • Innovations in Concrete and Construction Materials
  • Sensor Technology and Measurement Systems
  • Dynamics and Control of Mechanical Systems
  • Cancer-related Molecular Pathways
  • Systemic Lupus Erythematosus Research

"Dunarea de Jos" University of Galati
2011-2022

University of Medicine and Pharmacy of Craiova
2005-2019

University of Craiova
2014

Hai phong University Of Medicine and Pharmacy
2010

We are going through a period in which the concept of smart village (SV) is novelty for management community, and new economy based on power community support. Appropriately, development SV related to family’s participation motivation access education, increase knowledge information technology, communications technology (ICT) literacy, also creation facilities research (R&D). The partnership between public administration, private sector, heads will lead within village. At same time,...

10.3390/su141710723 article EN Sustainability 2022-08-29

Lignocelluloses residues from the post-harvest crop are receiving great scientific attention nowadays. Generally, composite materials based on lignocelluloses waste present low density and weight, better insulation properties compared with those petroleum-based. This study presents results of experimental investigations regarding soundproofing capabilities for a material expanded perlite (EP) natural polymers matrix (starch) reinforced rapeseed stalks waste. The preparation light-weight...

10.3390/su14010103 article EN Sustainability 2021-12-23

Podoplanin is involved in tumorigenesis and cancer progression head neck malignancies its expression not restricted to lymphatic vessel endothelium. The aim of this study was establish podoplanin the tumor-free resection margins oral squamous cell carcinomas (OSCCs) evaluate geometric complexity vessels mucosa by utilizing fractal analysis. As concerns noncancerous tissue, forty from OSCCs were investigated immunohistochemistry for D2-40 antibody image densitometry extremely low basal cells,...

10.14670/hh-25.701 article EN PubMed 2010-06-01

The objective of this study was to determine the visualizing rate fetal kidneys at various gestational ages in late first trimester (FT) and establish clinical significance their two-dimensional ultrasound (2DUS) appearance FT.In a prospective cross-sectional study, 1456 women from an unselected population underwent detailed assessment anatomy 11+0 -13+4 weeks gestation with use transabdominal sonography. Information on findings, antenatal course perinatal outcome obtained 1331 cases.44...

10.12865/chsj.42.01.03 article EN PubMed 2016-01-01

Epithelial-mesenchymal transition (EMT) is a fundamental process which governs invasiveness. E-cadherin plays major role in development, organogenesis and tissue formation, but also tumor progression. Snail transcription factor described as direct repressor of during development carcinogenesis. In this study we analyzed immunoexpression 47 cases colorectal adenocarcinoma (CRC) comparison with some histopathological prognostic factors. The majority were G2 tumors stages II III, vascular...

10.12865/chsj.45.02.12 article EN PubMed 2019-10-19

In this study, polysulphone (PSf) membranes were manufactured in different conditions to establish the influence of manufacturing factors on permeation properties PSf nanofiltration membranes. prepared by diffusion-induced phase inversion N-methyl-pyrrolidone (NMP) as solvent and deionized water coagulant. The relative air humidity casting time polymer process studied. All polymeric solutions at 30 wt% NMP a thin film 250 μm thickness was cast support wetted with NMP, tamp pores from...

10.1080/19443994.2015.1062435 article EN cc-by-nc-nd Desalination and Water Treatment 2015-07-06

Epithelial mesenchymal transition consists in the acquisition of neoplastic epithelial cells a phenotype process being involved cancers invasion and metastasis. In this study were analyzed expression N-cadherin, Twist Vimentin bladder urothelial carcinomas according to main prognostic parameters.The included 20 which histopathological, immunohistochemical statistical.N-cadherin was identified 45% cases, belonged high-grade with deep lymph node metastases. immunoreaction all cases...

10.12865/chsj.41.03.05 article EN PubMed 2015-07-01

The study aims to assess the correlation between stromal fibrillary component (SFC) and vascular density (VD) in Gleason architectural patterns of prostate carcinoma.680 digital images adenocarcinoma labeled following both Srigley systems were acquired with X20 objective from serial sections, one stained using Gömöri technique for SFC immunomarked anti-CD34 antibody vessels. amount VD determined compared. divided in: "Solid" group (Gleason 3a, 3b, 4b, 5b) "Necrotizing" 3c 4a 5a). For each...

10.12865/chsj.41.04.09 article EN PubMed 2015-10-01

Mobility challenges in rural areas can have a negative impact on economic and demographic development. People these often to move urban find quality jobs or services, which lead decline population, activity. In this paper we analyze the factors influencing business decisions areas. Public transport infrastructure based short energy cycles using solar represents solution boost decision management

10.5171/2024.714661 article EN Journal of Eastern Europe Research in Business & Economics 2024-10-15

Purpose The study authors have proposed to highlight the main epidemiologic and prognostic aspects of digestive malignancies in Dolj county population, justifying need for permanent detailed estimate this phenomenon. Methods outline a descriptive epidemiological panel, characteristic population groups at risk developing gastric cancers establishing clinical factors (tumor location, disease stage, type surgery) histological (histopathological type, degree tumor differentiation) with...

10.12865/chsj.42.03.04 article EN PubMed 2016-07-01

Renal cell clear carcinomas (ccRCC) represent 75% of the malignant renal neoplasias. A critical molecular characteristic in epithelial-mesenchymal transition (EMT) is loss E-cadherin expression, as well transcription factors, one most important which Snail. In current study, we analyzed immunoexpression two markers 46 cases carcinomas, with reference to prognosis histopathological factors. Our results indicated significant associations between overexpression Snail, under expression and high...

10.12865/chsj.45.02.09 article EN PubMed 2019-10-19

Oral squamous cells carcinoma (OSCC) mortality rate ranges between 29-40/100,000 inhabitants. Regional lymph node metastases occur in 30-40% cases and are associated with unfavorable prognosis decreased survival. Recentely it was suggested that the tumor-associated lymphatic vessels formation plays an active role metastasis proces of several human malignancies, including OSCC. In present study we investigated comparatively podoplanin immunoexpression OSCC both tumor reported to...

10.12865/chsj.41.02.07 article EN PubMed 2015-04-01

This paper presents a fuzzy quality certification of wheat. analysis is based on the model We developed Matlab application with help which we modeled perceptions in relation to main physical and chemical characteristics wheat obtaining index lots. The algorithm presented this article allows for using global index, generating applicability not only commercial sphere as reference price setting, but also measure appreciation processing opportunities. Indices associated lots offer opportunity...

10.3390/agriculture12101640 article EN cc-by Agriculture 2022-10-08

This work presents a practical solution intended for dynamic diagnosis of the technical systems based on set computational methods processing and analyzing acquired signals. ensemble leads to joint time-frequency evaluations assures multiple way estimate potential damages certain parts tested system. Short-Time-Fourier-Transformation, Cepstrum analysis, power spectral density estimate, together with group stochastic estimators composes structured procedure diagnosis. The proposed approach...

10.4028/www.scientific.net/amm.657.465 article EN Applied Mechanics and Materials 2014-10-01

The objective of this study was to determine the visualising rate fetal kidneys at various gestational ages in late first trimester (FT) and establish clinical significance their two-dimensional ultrasound (2DUS) appearance FT. In a prospective cross-sectional study, 1456 women from an unselected population underwent detailed assessment anatomy 11 + 0 –13 4 weeks gestation with use transabdominal sonography. Information on findings, antenatal course perinatal outcome obtained 1331 cases. 44...

10.1002/uog.15142 article EN Ultrasound in Obstetrics and Gynecology 2015-09-01

This paper provides a starting point for further study in the domain of analysis behavior pendulum absorber systems dynamic regime. Thus, one can determine an optimal configuration system to ensure efficiency isolation entire variation excitation.

10.4028/www.scientific.net/amm.801.165 article EN Applied Mechanics and Materials 2015-10-01
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