A5038713368- Cervical Cancer and HPV Research
- Alzheimer's disease research and treatments
- RNA modifications and cancer
- RNA and protein synthesis mechanisms
- Endometrial and Cervical Cancer Treatments
- Power Systems and Renewable Energy
- Advanced Algorithms and Applications
- Reproductive tract infections research
- Cancer-related molecular mechanisms research
- Anaerobic Digestion and Biogas Production
- RNA Research and Splicing
- Smart Grid and Power Systems
- Cerebrovascular and Carotid Artery Diseases
- Solar Thermal and Photovoltaic Systems
- Epigenetics and DNA Methylation
- Molecular Biology Techniques and Applications
- Endometriosis Research and Treatment
- Dementia and Cognitive Impairment Research
- Fault Detection and Control Systems
- DNA and Nucleic Acid Chemistry
- Reproductive System and Pregnancy
- Power Systems and Technologies
- Thermochemical Biomass Conversion Processes
- Folate and B Vitamins Research
- Genomics and Chromatin Dynamics
Dalian Polytechnic University
2022-2025
La Jolla Bioengineering Institute
2023-2024
University of California, San Diego
2023-2024
Affiliated Hospital of Qingdao University
2014-2024
Qingdao University
2013-2024
Zhengzhou University
2013-2024
China Southern Power Grid (China)
2009-2024
Henan Provincial People's Hospital
2019-2024
Children's Hospital of Fudan University
2024
Peking University
2014-2023
Abstract The apical hook is an essential structure that enables epigeal plants to protrude through the soil. Arabidopsis thaliana HOOKLESS1 (HLS1) reported be a key regulator of development and direct target gene ethylene (ET)-activated transcription factors ETHYLENE INSENSITIVE3 (EIN3) its close homolog EIN3-Like1. Previous research has shown phytohormones jasmonate (JA) ET antagonistically regulate development, although underlying molecular mechanism largely unknown. Here, we report JA...
The Coronavirus Disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is not only spreading throughout China but has reached more than 20 countries and already posed threats to global health economy. So far, number of people infected in climbed 70 000. Of them, at least 3019 healthcare workers have been infected. However, specific causes infection among hospital environments are unclear. It confirmed that COVID-19 mainly transmitted through both...
Abstract In situ transcriptomic techniques promise a holistic view of tissue organization and cell-cell interactions. There has been surge multiplexed RNA in mapping but their application to human tissues limited due large size, general lower quality high autofluorescence. Here we report DART-FISH, padlock probe-based technology capable profiling hundreds thousands genes centimeter-sized sections. We introduce an omni-cell type cytoplasmic stain that substantially improves the segmentation...
Abstract Cisplatin, one of the most widely used anticancer drugs, crosslinks DNA and ultimately induces cell death. However, genomic pattern cisplatin–DNA adducts has remained unknown owing to lack a reliable sensitive genome‐wide method. Herein we present “cisplatin‐seq” identify cisplatin crosslinking sites at base resolution. Cisplatin‐seq reveals that mitochondrial is preferred target cisplatin. For nuclear genomes, are enriched within promoters regions harboring transcription...
Significance Oxidative DNA damage can be cytotoxic or mutagenic to cells. NEIL1 (Nei-like 1) is a repair glycosylase guarding the mammalian genome against various oxidized bases; yet how recognizes and catalyzes removal of its substrates remains poorly understood. Here we integrate crystal structures NEIL1/double-stranded complex, computational simulations, biochemical analyses show that promotes tautomerization thymine glycol—a cognate substrate—for efficient substrate recognition excision....
The effects of chemical composition (carbohydrates, lipids, and protein) on the anaerobic co-digestion performance food wastes (FW) were investigated from viewpoints methane production, dynamic parameters, microbial community structure. results this study showed that a notable gasification rate was positively correlated with proportion composition. A T2 reactor, which consisted 60% carbohydrates, 20% protein, held higher 65.09% compared to other groups, while its process parameters some...
Abstract INTRODUCTION We analyzed relationships among peripheral immunity markers, cognition, Alzheimer's disease (AD)‐related biomarkers, and neuroimaging to understand involvement in AD. METHODS Peripheral markers were assessed AD, non‐AD neurodegenerative disorders, controls, examining their connections with AD‐related using multiple regression models. RESULTS The study included 1579 participants. Higher levels of white blood cell, neutrophil, monocyte, neutrophil‐to‐lymphocyte ratio...