A5011751029- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Spinal Fractures and Fixation Techniques
- Cervical and Thoracic Myelopathy
- Medical Imaging and Analysis
- Management of metastatic bone disease
- Anesthesia and Pain Management
- Antibiotic Resistance in Bacteria
- Spinal Hematomas and Complications
- Gut microbiota and health
- Clostridium difficile and Clostridium perfringens research
- Antibiotic Use and Resistance
- Nosocomial Infections in ICU
- Orthopaedic implants and arthroplasty
- Clinical practice guidelines implementation
- Mycobacterium research and diagnosis
- Mesenchymal stem cell research
- Bone and Joint Diseases
- Complementary and Alternative Medicine Studies
- Opioid Use Disorder Treatment
- Plant Toxicity and Pharmacological Properties
- Lung Cancer Diagnosis and Treatment
- Urinary Tract Infections Management
- Pregnancy-related medical research
- Nerve injury and regeneration
Rush University Medical Center
2014-2025
Rush University
2016
Midwest Orthopaedic Research Foundation
2016
West Virginia University
2015
University of California, San Francisco
2015
Durango Institute of Technology
2015
Yale University
2015
University of Pittsburgh Medical Center
2015
University of California, Irvine
2015
Degenerative changes in the intervertebral disc (IVD) are known to be a main cause of low back pain (LBP), oftentimes necessitating interventions that may or not successful due lack understanding degenerative phenotype and its mechanisms. Understanding molecular mechanisms degeneration can help design new therapies induce regeneration reduce pain. This work aimed understand effects conditional deletion Sox9 aggrecan-expressing cells on underlying mice. study utilized Agc1-CreERT2;Sox9...
Abstract Background Lumbar degenerative spondylolisthesis (LDS), characterized as degeneration of the intervertebral disc and structural changes facet joints, is a condition with varying degrees instability that may lead to pain, canal stenosis, subsequent surgical intervention. However, etiology LDS remains inconclusive. Gut microbiome dysbiosis stimulate systemic inflammation in various disorders. role such upon spine health under‐studied. The current study assessed association gut...
Little is known about the accuracy of reporting preoperative narcotic utilization in spinal surgery. As such, purpose this study to compare postoperative consumption between utilizers who do and not accurately self-report utilization.Patients underwent anterior cervical discectomy fusion, minimally invasive lumbar discectomy, or transforaminal interbody fusion procedures 2013 2014 were prospectively identified. The self-reporting was determined utilizing Illinois Prescription Monitoring...
Retrospective cohort analysis of a prospectively maintained registry.To compare the surgical outcomes, narcotic utilization, and costs between stand-alone (SA) cage anterior plating (AP) with an interbody device for 1-level cervical discectomy fusion (ACDF).ACDF SA has gained popularity as potential alternative to plating. Few studies have compared ACDF utilizing versus AP device.Patients who underwent primary degenerative spinal pathology 2010 2013 were analyzed. Patients stratified on...
Retrospective cohort analysis of a prospectively maintained registry.To compare the intraoperative variables, surgical outcomes, and narcotic utilization between primary revision 1-level minimally invasive (MIS) lumbar discectomies.Revision spine surgery may be associated with longer procedural time greater soft tissue disruption. Few studies have analyzed outcomes MIS discectomies.A retrospective 227 consecutive cases discectomy for degenerative spinal pathology 2009 2014 by single surgeon...
In Brief Study Design. Retrospective matched pair cohort analysis using a prospectively maintained registry. Objective. To describe the findings associated with workers' compensation (WC) claimants in regard to surgical outcomes, costs, and reimbursement after 1- or 2- level anterior cervical discectomy fusion. Summary of Background Data. WC patients are perceived demonstrate poor outcomes greater health care expenditure than more traditional patients. This study aims evaluate differences...
Computed tomographic analysis.To identify radiographic patterns of symptomatic neuroforaminal bone growth (NFB) in patients who have undergone a single-level minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) augmented with morphogenetic proteins (BMP) utilizing computed tomography (CT).BMP induces osteoblast differentiation leading to new formation. The association BMP utilization and heterotopic formation after an MIS-TLIF has been described. However, studies limited...
Study Design: This is a retrospective analysis. Objective: To test the hypothesis that there limited utility in routinely obtaining postoperative laboratory values following minimally invasive transforaminal lumbar interbody fusion (MIS TLIF). Background Data: At many institutions, it routine to obtain complete blood count and basic metabolic profile (BMP) MIS TLIF. However, of this practice has not been well characterized. Methods: A total 332 consecutive patients who underwent primary,...
Retrospective cohort analysis of a prospective registry.To assess the differences in perioperative narcotic consumption between Workman's compensation (WC) and non-Workman's (non-WC) patients after single-level minimally invasive transforaminal lumbar interbody fusion.There is concern regarding potential overutilization opioid pain medication WC patients. However, impact status on spine procedures has not been previously reported.A who underwent primary 1-level fusion for degenerative spinal...
Minimally invasive (MIS) techniques have gained considerable attention for the management of degenerative spinal pathologies. However, few studies compared outcomes between MIS and open thoracolumbar corpectomies. The purpose this study was to compare perioperative variables corpectomy.Retrospective review 33 patients who underwent either an or corpectomy by a single surgeon 2005 2012 performed. Patients were separated into anterior-posterior (MIS AP), (AP), posterior (P) cohorts....
Study Design. Retrospective review of prospectively collected data. Objective. The aim the study was to characterize outcomes functional capacity evaluations (FCEs) amongst patients undergoing spinal fusion surgery. Summary Background Data. Injured workers often undergo an FCE upon reaching maximal medical improvement following To date, few studies have examined results FCEs fusion. Methods. Patients a minimally invasive transforaminal lumbar interbody (TLIF) or anterior cervical discectomy...
Admission and discharge screening of patients for asymptomatic gut colonization with multidrug-resistant organisms (MDROs) is a traditional approach to active surveillance, but its sensitivity detecting uncertain.
Recentadvances in spine surgery technology and instrumentation have allowed for the development of minimally invasive (MIS) techniques. These muscle-sparing approaches been demonstrated to provide superior, if not similar, outcomes traditional open However, MIS techniques are associated with a steep learning curve greater radiation exposure. Furthermore, while suitable most degenerative spinal conditions, may be appropriate complex pathology. This articlediscusses literature onopen advanced...