A5047909741- Trace Elements in Health
- Nanoparticle-Based Drug Delivery
- Electrochemical Analysis and Applications
- Chemical Reactions and Isotopes
- Iron Metabolism and Disorders
- Drug Transport and Resistance Mechanisms
- Chemical Reactions and Mechanisms
- Bone Tissue Engineering Materials
- Chemical Reaction Mechanisms
- Characterization and Applications of Magnetic Nanoparticles
- Cerebrovascular and Carotid Artery Diseases
- Asymmetric Hydrogenation and Catalysis
- Mass Spectrometry Techniques and Applications
- Electrochemical sensors and biosensors
- Biosensors and Analytical Detection
- X-ray Spectroscopy and Fluorescence Analysis
- Boron Compounds in Chemistry
- Nanoplatforms for cancer theranostics
- Molecular Sensors and Ion Detection
- Advanced Nanomaterials in Catalysis
Oregon Health & Science University
2024-2025
Reed College
2021
Iron is an essential element for life owing to its ability participate in a diverse array of oxidation–reduction reactions. However, misregulation iron-dependent redox cycling can also produce oxidative stress, contributing cell growth, proliferation, and death pathways underlying aging, cancer, neurodegeneration, metabolic diseases. Fluorescent probes that selectively monitor loosely bound Fe(II) ions, termed the labile iron pool, are potentially powerful tools studies this metal nutrient;...
Copper is an essential nutrient for sustaining vital cellular processes spanning respiration, metabolism, and proliferation. However, loss of copper homeostasis, particularly misregulation loosely bound ions which are defined as the labile pool, occurs in major diseases such cancer, where tumor growth metastasis have a heightened requirement this metal. To help decipher role etiology we report histochemical activity-based sensing approach that enables systematic, high-throughput profiling...
Molecular imaging with analyte-responsive probes offers a powerful chemical approach to studying biological processes. Many reagents for bioimaging employ fluorescence readout, but the relatively broad emission bands of this modality and need alter structure fluorophore different signal colors can potentially limit multiplex imaging. Here, we report generalizable analyte by leveraging comparably narrow spectral signatures stimulated Raman scattering (SRS) in activity-based sensing (ABS)...
Molecular imaging with analyte-responsive probes offers a powerful chemical approach to study biological processes. The most common types of reagents for bioimaging employ fluorescence readout, but the relatively broad emission bands this modality and need alter structure fluorophore achieve different signal colors can potentially limit multiplex imaging. Here we report generalizable analyte by leveraging comparably narrow spectral signatures stimulated Raman scattering (SRS) in an...
The synthesis of water-soluble nanoparticles is a well-developed field for ferrite-based with the majority consisting iron oxide or mixed metal nanoparticles. However, non-agglomerated non-ferrite metal/metal NPs not as well established. and characterization uniform 20 nm, biologically compatible cobalt (CoO) (NPs) described. These have two principle components: 1) CoO core suitable size to contain enough atoms be visualized by X-ray fluorescence microscopy (XFM) 2) robust coating that...
<title>Abstract</title> The synthesis of water-soluble nanoparticles is a well-developed field for ferrite-based with the majority consisting iron oxide or mixed metal nanoparticles. However, non-agglomerated non-ferrite metal/metal NPs not as well established. and characterization uniform 20 nm, biologically compatible cobalt (CoO) (NPs) described. These have two principle components: 1) CoO core suitable size to contain enough atoms be visualized by X-ray fluorescence microscopy (XFM) 2)...