Weiwei Gao

ORCID: 0000-0002-4170-3138
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Research Areas
  • Ginseng Biological Effects and Applications
  • Plant Pathogens and Fungal Diseases
  • Mycotoxins in Agriculture and Food
  • Plant Disease Resistance and Genetics
  • Agriculture, Soil, Plant Science
  • Traditional Chinese Medicine Analysis
  • Plant and fungal interactions
  • Plant-Microbe Interactions and Immunity
  • Food Quality and Safety Studies
  • Plant pathogens and resistance mechanisms
  • Pesticide Residue Analysis and Safety
  • Plant Disease Management Techniques
  • Fungal Biology and Applications
  • Remote Sensing and Land Use
  • Plant tissue culture and regeneration
  • Plant Molecular Biology Research
  • Phytochemical Studies and Bioactivities
  • Traditional Chinese Medicine Studies
  • Horticultural and Viticultural Research
  • Powdery Mildew Fungal Diseases
  • Analytical Chemistry and Chromatography
  • Allelopathy and phytotoxic interactions
  • Wheat and Barley Genetics and Pathology
  • Ethnobotanical and Medicinal Plants Studies
  • Phytochemistry and biological activity of medicinal plants

Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2025

Shihezi University
2024-2025

State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2023

South China Botanical Garden
2021-2023

Chinese Academy of Sciences
2023

Guangxi University
2023

Peking University
2009-2022

Second Affiliated Hospital of Zhengzhou University
2022

University of Chinese Academy of Sciences
2021-2022

Peking University Cancer Hospital
2009-2022

Abstract Mediating induced abscisic acid (ABA) biosynthesis is important for enhancing plant stress tolerance. Here, we found that rice (Oryza sativa L.) osa–miR2105 (miR2105) and the Stress/ABA-activated protein kinase (OsSAPK10) coordinately regulate basic region-leucine zipper transcription factor (bZIP TF; OsbZIP86) at posttranscriptional posttranslational levels to control drought-induced ABA via modulation of 9-cis-epoxycarotenoid dioxygenase (OsNCED3) expression. OsbZIP86 expression...

10.1093/plphys/kiac071 article EN PLANT PHYSIOLOGY 2022-02-18

Two hundred 1-day-old male commercial Arbor Acres broiler birds were randomly distributed to a control group and polysavone (5 replicates of 20 each) investigate the influence polysavone, natural extract from alfalfa, on abdominal fat deposition immunity in chickens. Birds supplied with basal diet, 0.06% was added diet group. Body weight feed consumption for each replicate recorded weekly. At 3, 4, 5, 6 wk age, 4 selected blood organ sampling. Polysavone had no significant effect intake, BW,...

10.1093/ps/86.9.1955 article EN cc-by-nc-nd Poultry Science 2007-09-01

Abstract Background High-flow nasal cannula (HFNC) can improve ventilatory function in patients with acute COPD exacerbation. However, its effect on clinical outcomes remains uncertain. Methods This randomized controlled trial was conducted from July 2017 to December 2020 16 tertiary hospitals China. Patients exacerbation mild hypercapnia (pH ≥ 7.35 and arterial partial pressure of carbon dioxide > 45 mmHg) were randomly assigned either HFNC or conventional oxygen therapy. The primary...

10.1186/s13054-022-03973-7 article EN cc-by Critical Care 2022-04-15

Herbs derived from roots, leaves, flowers, or fruits of plants are unavoidably contaminated with fungi and mycotoxins during growth, harvest, storage, thereby posing a health threat to humans. Especially, root herbs (RHs) more easily because the roots in direct contact soil. Here, we investigated occurrence fungi, aflatoxins (AFs), ochratoxin A (OTA) eight RHs that used as medicines, beverages, dietary supplements, functional foods China other countries. Morphological observation...

10.4315/0362-028x.jfp-17-405 article EN cc-by-nc-nd Journal of Food Protection 2018-04-05

The production of American ginseng (Panax quinquefolius L.) is severely limited by the replant disorders in China. Crop rotation with maize might reduce problems, but little information available on effect soil cultivated ginseng. In this study, we analyzed nutrients, phenolic acids, and microbial communities soils from fields continuous maize, mono-culture ginseng, 1-, 3-, 5-year after Pot experiments were also conducted to evaluate performance replanting these soils. results showed that...

10.1038/s41598-019-44530-7 article EN cc-by Scientific Reports 2019-06-13

The volatile compounds produced by plants play an important role in plant growth, communication, and resistance to biological abiotic stresses. Astragalus membranaceus var. mongholicus (AM) is a perennial herbaceous (Leguminosae) that widely cultivated northwest China. bioactive its root have shown various pharmacological activities. Root rot disease caused Fusarium spp. often occurs AM planting with increasing severity continuous monoculture. It currently still unclear what are the effects...

10.3390/plants13020317 article EN cc-by Plants 2024-01-20

The root rot disease causes a great economic loss, and the severity usually increases as ginseng ages. However, it is still unclear whether related to changes in microorganisms during entire growing stage of American ginseng. present study examined microbial community rhizosphere chemical properties soil 1-4-year-old plants grown different seasons at two sites. Additionally, investigated plants' index (DI). results showed that DI increased 2.2 times one sampling site 4.7 another 4 years....

10.3389/fmicb.2023.1097742 article EN cc-by Frontiers in Microbiology 2023-02-14

Astragalus membranaceus var. mongholicus (AMM) is a widely used medicinal plant in China, primarily cultivated the northern regions; however, selection and breeding of superior varieties remains underdeveloped. To scientifically assess germplasm resources AMM facilitate its breeding, this study collected 33 samples from five provinces conducted comprehensive evaluation their botanical traits, agronomic quality powdery mildew resistance. The results indicated that, among 18 Shannon–Wiener...

10.3390/horticulturae11030317 article EN cc-by Horticulturae 2025-03-13

The multi-mycotoxin occurrence for internal and superficial fungi contamination were comprehensively assessed in medicinal seeds used as food or beverage. Based on a polyphasic approach using morphological characters, β-tubulin ITS gene blast, total of 27 species belonging to 12 genera identified from surface-sterilized seeds. Chaetomium globosporum was most predominant (23%), followed by Microascus trigonosporus (12%) Alternaria alternata (9%). With respect mycobiota, thirty-four 17...

10.3390/toxins7103858 article EN cc-by Toxins 2015-09-24

In this research, fifteen carbamate pesticide residues were systematically analyzed by ultra-high performance liquid chromatography⁻quadrupole-linear ion trap mass spectrometry on a QTRAP 5500 system in both multiple reaction monitoring (MRM) and enhanced product (EPI) scan modes. The extracted from variety of samples QuEChERS method separated popular reverse phase column (Waters BEH C18). Except for the current conformation criteria including selected pairs, retention time relative...

10.3390/molecules23102496 article EN cc-by Molecules 2018-09-29

American ginseng (Panax quinquefolius L.) is a highly valuable herb widely used for medicinal treatments. Its pharmacologically important compounds are the ginsenosides, which secondary metabolites in root. The concentrations of ginsenoside roots can be changed by fungal infection, but it unclear what specific root tissues impacted and whether change systemic. In this study, were inoculated with two pathogens (Fusarium solani or F. oxysporum) levels six ginsenosides (Rb1, Rb2, Rc, Rd, Re,...

10.3390/molecules200610535 article EN cc-by Molecules 2015-06-08

Mercury (Hg) causes severe nephrotoxicity in subjects with excess exposure. This work attempted to identify whether a natural medicine—rhubarb—has protective effects against mercuric chloride (HgCl2)-induced acute renal failure (ARF), and which of its components contributed most the treatment. Total rhubarb extract (TR) were separated total anthraquinones (TA), tannins (TT) remaining component (RC). Each was orally pre-administered rats for five successive days followed by HgCl2 injection...

10.3390/molecules21030298 article EN cc-by Molecules 2016-03-08

Fungi associated with ochratoxin A (OTA)-contaminated liquorice root and their capabilities for OTA production were investigated. Medicinal materials of mouldy collected from herbal markets located in Jiangxi, Zhejiang, Henan provinces Beijing, China, respectively. Sixteen fungal species belonging to Penicillium, Aspergillus, Eurotium, Fusarium, Mucor Scopulariopsis isolated; the composition was different each sample. Penicillium polonicum predominant, comprising 54% total isolates sample...

10.1080/19440049.2011.576443 article EN Food Additives & Contaminants Part A 2011-07-27

The hepatotoxicity induced by Polygoni Multiflori Radix Praeparata (PM) has aroused great concern throughout the world. Hence, it is worthwhile to perform studies on detoxification with combined use of medicinal herbs based compatibility theory traditional Chinese medicine. In this work, rat model PM/LPS-induced idiosyncratic liver injury was used. effects Poria, Licorice, and Panax notoginseng rats were investigated respectively, hoping find most effective herbal medicine reduce...

10.3389/fphar.2016.00386 article EN cc-by Frontiers in Pharmacology 2016-10-18

To design the Aspergillus flavus and parasiticus-specific primers a real-time PCR assay for quantification of conidial density in soil.Aspergillus A. DNA were designed based on internal transcribed spacer sequences to distinguish these two species from other fungal species. A method pathogen extraction directly soil samples was developed. Using primers, developed quantitatively determine each parasiticus soil, after generating corresponding standard curves. Known densities or significantly...

10.1111/j.1365-2672.2008.04132.x article EN Journal of Applied Microbiology 2009-02-16

ABSTRACT The replant problem is a widespread challenge in agricultural production and results significant financial losses. survival development of American ginseng ( Panax quinquefolius L.), well-known perennial medicinal plant, also typically suffer from problems. At present, efficient strategies for this issue the underlying mechanisms are still lacking. Here, series situ field experiments over 4-year period were conducted to investigate effectiveness possible soil fumigation fungicide...

10.1128/spectrum.01757-23 article EN cc-by Microbiology Spectrum 2024-01-11

Developing evidence-based uses of herbal medicines and natural product-based drug discovery are two core aims ethnopharmacology. This requires an understanding the medicinal plants traditional medical knowledge associated with them which is a basis for cross-cultural comparison. The botanical drugs systems still not understood well, even well-known widely respected traditions like Ayurveda. In this study, quantitative ethnobotanical analysis was performed on single included in Ayurvedic...

10.3389/fphar.2023.1136446 article EN cc-by Frontiers in Pharmacology 2023-05-11

When insects harm plants, they activate relevant enzyme systems for defense, and changes in activity, to a certain extent, reflect the host plant's ability resist insect damage. Alfalfa leaf weevils (Hypera postica Gyllenhal) are main economic pest of alfalfa, which seriously affect its yield quality. To clarify effects feeding induction by alfalfa weevil larvae adults on defense enzymes 'Zhongmu No. 1' variety was used as experimental material. Comprehensive correlation analysis principal...

10.1371/journal.pone.0312612 article EN cc-by PLoS ONE 2024-11-08
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