A5028319591- RNA and protein synthesis mechanisms
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- RNA Research and Splicing
Sun Yat-sen University
2022
Abstract Although the function of tRNAs in translational process is well established, it remains controversial whether tRNA abundance tightly associated with efficiency (TE) mammals. Moreover, how critically expression contributes to establishment tissue-specific proteomes mammals has not been addressed. Here, we measured both using demethylase-tRNA sequencing (DM-tRNA-seq) and TE mRNAs ribosome-tagging (RiboTag-seq) brain, heart, testis mice. Remarkable variation isodecoders was observed...
Abstract Although the function of tRNA in translational process is well established, it remains controversial whether abundance tightly associated with efficiency (TE) mammals. For example, how critically expression tRNAs contributes to establishment tissue-specific proteomes mammals has not been addressed. Here, we measured both using DM-tRNA-seq and ribosome-associated mRNAs brain, heart, testis RiboTag mice. Remarkable variation isodecoders was observed among different tissues. When...