Melahat Melek Oğuz

ORCID: 0000-0002-4196-4469
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About
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Research Areas
  • Respiratory viral infections research
  • Vaccine Coverage and Hesitancy
  • Autoimmune and Inflammatory Disorders Research
  • Metabolism and Genetic Disorders
  • Pulmonary Hypertension Research and Treatments
  • Streptococcal Infections and Treatments
  • Influenza Virus Research Studies
  • Medical Imaging and Pathology Studies
  • Vascular Anomalies and Treatments
  • Abdominal Trauma and Injuries
  • Inflammasome and immune disorders
  • Glycogen Storage Diseases and Myoclonus
  • Impact of Technology on Adolescents
  • Pneumonia and Respiratory Infections
  • Cystic Fibrosis Research Advances
  • Amino Acid Enzymes and Metabolism
  • Bacterial Infections and Vaccines
  • Bone health and treatments
  • Bacillus and Francisella bacterial research
  • Parvovirus B19 Infection Studies
  • Virology and Viral Diseases
  • Vascular Malformations and Hemangiomas
  • Child Development and Digital Technology
  • Bone Metabolism and Diseases
  • Immune responses and vaccinations

Ministry of Health
2014-2024

Sağlık Bilimleri Üniversitesi
2020-2024

University of Health Science
2024

Children's Research Hospital
2024

Dr Sami Ulus Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi
2014-2022

Pediatrics and Genetics
2018

İstanbul Eğitim ve Araştırma Hastanesi
2015

Ankara Onkoloji Eğitim ve Araştırma Hastanesi
2014

Gazi University
2014

Ankara Atatürk Göğüs Hastalıkları Ve Göğüs Cerrahisi Eğitim Ve Araştırma Hastanesi
2014

Abstract Background Baby‐led weaning ( BLW ) is an approach to introducing solid foods infants that gives control of the feeding process infant. Anecdotal evidence suggests becoming popular with parents, but scientific research limited a few publications. This study assessed growth, hematological parameters and iron intake in 6–12‐month‐old fed by traditional or baby‐led complementary feeding. Methods We recruited 280 healthy 5–6‐month‐old allocated (traditional spoon feeding; TSF group...

10.1111/ped.13671 article EN Pediatrics International 2018-08-07

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome of excessive immune activation. Secondary HLH develops as complication infection, drugs, rheumatologic conditions, or malignancy. The main objectives this work were to identify the etiology secondary and prognostic factors associated with mortality. Patients diagnosed HLH, between January 2011 December 2016, retrospectively included in study. We analyzed clinical laboratory findings well from 24 pediatric patients HLH....

10.1080/08880018.2019.1572253 article EN Pediatric Hematology and Oncology 2019-01-02

Children are at higher risk of influenza complications. The goals this article are, estimating vaccination coverage Health Care Workers (HCWs) in tertiary children hospital, evaluating attitudes and practices HCWs whether uptake improved with onsite campaign. This was a before-after trial, which carried out hospital 2017-2018 season. team visited all participants collected information about previous uptake, beliefs by means an anonymous questionnaire. Moreover, the vaccine offered to...

10.1080/21645515.2019.1575164 article EN Human Vaccines & Immunotherapeutics 2019-02-08

Glycogen synthase deficiency, also known as glycogenosis (GSD) type 0 is an inborn error of glycogen metabolism caused by mutations in the GYS2 gene, which transmitted autosomal recessive trait. It a rare form hepatic storage disease with less than 30 cases reported literature so far. The disorder characterized fasting hyperketotic hypoglycemia without hyperalaninemia or hyperlactacidemia. lack liver synthesis, therefore hepatomegaly not observed patients deficiency. Symptoms (GSD0) usually...

10.1515/jpem-2016-0317 article EN Journal of Pediatric Endocrinology and Metabolism 2017-01-01

During the initial half-year of their existence, infants cannot receive influenza vaccine, yet they face greatest susceptibility to severe complications. In this study, we seek determine whether vaccination maternal and household contacts is associated with a reduced risk influenza-like illness (ILI) acute respiratory infection (SARI) in infants. This work was prospectively conducted during season. A total 206 were included study. The percentage only mother vaccinated 12.6% (n:26), percent...

10.1080/21645515.2024.2350090 article EN cc-by-nc Human Vaccines & Immunotherapeutics 2024-05-13

This prospective cross-sectional study attempted to determine both the usefulness of serum intercellular adhesion molecule-1 (ICAM-1) as a biomarker for pulmonary artery hypertension secondary congenital heart disease and nature this marker's association with catheter angiographic findings. Our included total 70 male female children, comprising 30 patients disease, 20 alone, healthy control subjects. Levels ICAM-1 in plasma samples from all groups were measured by enzyme-linked immunosorbent...

10.14503/thij-12-3012 article EN Texas Heart Institute Journal 2014-04-01

Chryseobacterium indologenes is a rare cause of infection in children. The organism causes infections mostly hospitalised patients with severe underlying diseases. choice an effective drug for the treatment due to C. difficult as has limited spectrum antimicrobial sensitivity. We present case nosocomial septicemia caused by infant congenital heart disease who was successfully treated trimethoprim sulfamethoxazole and also reviewed fourteen additional cases reported English literature this report.

10.1155/2014/270521 article EN cc-by Case Reports in Infectious Diseases 2014-01-01

The pathogenesis of juvenile idiopathic arthritis (JIA) remains unknown, but imbalance between the oxidant and antioxidant defense systems may play a role. Measuring thiols in plasma provides an indirect indication antioxidative defense. aim present study was to investigate association JIA dynamic thiol/disulfide homeostatic status.This case-control involved 34 patients 30 age- gender-matched healthy controls. were divided into subgroups according Simplified Disease Activity Index (SDAI)...

10.1111/ped.13569 article EN Pediatrics International 2018-03-23

Objectives Lumbar puncture (LP) is fundamental for diagnosis and treatment; however, some parents do not provide consent their children to undergo the procedure, which can make determination of optimal treatment difficult. The present study aimed describe level knowledge attitudes toward LP whose were scheduled procedure. Methods A prospective cross-sectional descriptive a convenience sample 84 aged 2 months 17 years at single academic children's hospital between 2015 2017. Parents...

10.1097/pec.0000000000001594 article EN Pediatric Emergency Care 2018-09-22

Measles is one of the important vaccine-preventable diseases with many complications in childhood. This study presents cross-sectional seroepidemiological data, beginning from neonatal cord blood infants to children under 6 years age, about waning measles antibody and tries suggest proper time for immunization.A total 564 samples consisting taken at ages 6, 9, 24–48, 49–72 months were analyzed seropositivity a period months.Measles rate was 72.5% 109 samples, 2.6% 117 3.6% 111 9 age....

10.3906/sag-1809-54 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2019-02-11

Amaç: Human Papilloma Virüs (HPV) serviks kanserinin en sık nedenidir. Serviks kanserini ve HPV ilişkili diğer hastalıkları önlemede aşılama birincil olarak etkili yöntemdir. Bu çalışmanın amacı ebeveynlerin aşısı hakkındaki bilgi düzeyleri yaklaşımlarını değerlendirmektir. Gereç Yöntemler: Tanımlayıcı olan bu çalışma Aralık 2018-Ocak 2019 tarihlerinde 9-18 yaş arası kız çocuğuna sahip 203 ebeveyn üzerinde yapılmıştır. Ebeveynlerin demografik verileri, bilgileri aşılamasına ilişkin...

10.12956/tchd.515713 article TR Turkish Journal of Pediatric Disease 2019-03-12

Kikuchi–Fujimoto disease (KFD) is a histiocytic necrotising lymphadenitis characterised by painful cervical lymphadenopathy, fever, malaise and weight loss. Infections, auto-immune pathogenesis genetic association have been implicated. A 12-year-old boy presented with 1-month history of abdominal pain, constipation loss, lymph node was detected in the right axilla. Chest CT demonstrated multiple nodes, especially left mediastinum. Salmonella enteritidis group D blood culture he treated...

10.1080/20469047.2017.1420523 article EN Paediatrics and International Child Health 2018-01-08

Social contact between individuals is believed to be a fundamental cause in the transmission of many respiratory tract infections. Because they have not yet been fully vaccinated, infants are at high risk for contracting whooping cough, influenza and their serious complications. Therefore, determining infant social patterns an important step protecting them from infection. This study included 1200 healthy (<12 months age). diaries were used estimate frequency nature infants' contacts. survey...

10.1017/s0950268818001048 article EN Epidemiology and Infection 2018-05-09

Abstract Colchicine is an anti-inflammatory drug that has a narrow therapeutic index. Poisoning typically shows 3 phases with systemic symptoms. Gastrointestinal symptoms dominate in the first phase. Dermatologic manifestations usually appear, skin eruptions second phase where multiorgan failure occurs and alopecia third organ derangements resolve. Alopecia cardinal feature of phase, but there no specifically defined eruption for toxication. Here, we report case colchicine intoxication...

10.1097/pec.0000000000001530 article EN Pediatric Emergency Care 2018-06-15

Cow's milk allergy is the most common food in children. Symptoms usually involve skin and gastrointestinal respiratory tracts. Gastrointestinal tract manifestations of cow's are nonspecific, only type that can be diagnosed all age groups. Here, we report a rare case an infant with hypoalbuminemia malnutrition.A nine-month-old girl was admitted to Dr. Sami Ulus maternity children's health diseases training research hospital, Ankara, Turkey, September 2013, for weakness swelling legs had...

10.5812/ircmj.34810 article EN cc-by-nc Iranian Red Crescent Medical Journal 2016-05-17

Rotavirus is a leading cause of acute gastroenteritis in children. Although the clinical complaints associated with rotavirus are generally gastrointestinal, including vomiting and diarrhea, data suggest that it can also symptoms extend beyond gastrointestinal tract.We report three pediatric cases infection: one accompanied by encephalopathy two elevated hepatic transaminase activity. The patients were admitted to Dr. Sami Ulus maternity children's health diseases training research hospital,...

10.5812/ircmj35086 article EN Iranian Red Crescent Medical Journal 2016-06-14
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