About
Contact & Profiles
A5020291567
Research Areas
- Prenatal Substance Exposure Effects
- Heme Oxygenase-1 and Carbon Monoxide
- MicroRNA in disease regulation
Children's Hospital of Chongqing Medical University
2017
Chongqing Medical University
2017
Prenatal alcohol exposure may cause cardiac development defects, however, the underlying mechanisms are not yet clear. In present study we have investigated roles of histone modification by curcumin on induced fetal abnormalities during development. Q-PCR and Western blot results showed that increased gene active forms caspase-3 caspase-8, while decreased protein bcl-2. ChIP assay that, acetylation H3K9 near promoter region TUNEL data revealed apoptosis levels in embryonic hearts. vitro...
10.1186/s12929-016-0310-z
article
EN
cc-by
Journal of Biomedical Science
2017-01-05
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