A5072422692- Ethics in Clinical Research
- Ethics in medical practice
- BRCA gene mutations in cancer
- Ethics and Legal Issues in Pediatric Healthcare
- Global Cancer Incidence and Screening
- Health, Medicine and Society
- Genomics and Rare Diseases
- Healthcare Systems and Practices
- Biomedical Ethics and Regulation
- Reproductive Health and Technologies
- Nutrition, Genetics, and Disease
- Education, sociology, and vocational training
- Colorectal Cancer Screening and Detection
- Palliative Care and End-of-Life Issues
- Prenatal Screening and Diagnostics
- Social Representations and Identity
- Disaster Response and Management
- Patient-Provider Communication in Healthcare
- Social Sciences and Governance
- Clinical practice guidelines implementation
- Cultural Insights and Digital Impacts
- HIV/AIDS drug development and treatment
- French Urban and Social Studies
- Global Public Health Policies and Epidemiology
- Diverse multidisciplinary academic research
Université Paris-Est Créteil
2016-2025
Paris-Est Sup
2025
Economic & Social Sciences, Health Systems & Medical Informatics
2023-2025
Aix-Marseille Université
2023-2025
Inserm
2013-2024
École des hautes études en sciences sociales
2004-2024
Institut de Recherche Interdisciplinaire sur les Enjeux Sociaux
2013-2024
Centre National de la Recherche Scientifique
2009-2024
Institut de Recherche pour le Développement
2023-2024
Campus Condorcet
2021-2024
Abstract Background The MyPeBS study is an ongoing randomised controlled trial testing whether a risk-stratified breast cancer screening strategy non-inferior, or eventually superior, to standard age-based at reducing incidence of stage 2 more cancers. This large European Commission-funded initiative aims include 85,000 women aged 40 70 years, without prior and not previously identified high risk in six countries (Belgium, France, Italy, Israel, Spain, UK). A specific work package within...
Abstract In paediatric oncology, genomics raises new ethical, legal and psychological issues, as somatic constitutional situations intersect throughout the care pathway. The discovery of potential predisposition in this context is sometimes carried out outside usual framework. This article focuses on views children, adolescents, young adults (AYA) with cancer their parents about experience genomic testing. Forty-eight semi-structured interviews were performed children or AYAs one parents,...
<ns4:p>An international workshop was held in Leuven, Belgium, on June 19–20, 2023, to discuss the communication of genetic risk information within families context personalized prevention. Organized as part Horizon Europe project PROPHET (PeRsOnalised Prevention roadmap for future HEalThcare Europe), event gathered interdisciplinary stakeholders explore benefits and challenges various policy approaches returning test results with implications family members. Five key themes emerged from...
A survey conducted by the European Society of Breast Imaging (EUSOBI) in 2023 revealed significant variations Quality Assurance (QA) practices across Europe. The UK encourages regular performance monitoring for screen readers. This study aimed to assess variability diagnostic among readers participating a wider prospective randomised trial multiple countries. In this retrospective multinational study, breast imaging from MyPeBS clinical examined test set 40 challenging screening cases using...
Abstract Background To evaluate the acceptability of a risk-based breast cancer screening (BCS) strategy among professionals involved in MyPeBS study 6 countries. Methods After qualitative interviews, questionnaire was built with Delphi method: to professionals’ basic understanding, satisfaction and reactions each stage trial, opinions on BCS its future. The distributed by emailing 698 investigators, who forwarded it all categories trial recruitment (physicians, medical secretaries, nurses,...
Abstract The benefit of disclosing test results to next kin is improve prognosis and—in some cases—even prevent death though earlier monitoring or preventive therapies. Research on this subject has explored the question intra‐familial communication from standpoint patients and relatives but rarely, healthcare professionals. purpose study was interview relevant professionals in France, where legislation framing issue recently passed. A qualitative consisting semi‐structured interviews set up...
Breast cancer is a major public health challenge. Organized mammography screening (OS) considered one way to reduce breast mortality. EU recommendations prone mass deployment of OS, and back in 2004, France introduced national OS programme for women aged 50-74 years. However, 2012, participation rate was still just 52.7%, well short the targeted 70% objective. In an effort re-address (in) efficiency programme, French National Cancer Institute has drafted expert-group review ethical issues...
ABSTRACT Introduction Qualitative research on the perceptions of healthcare professionals involved in cancer care about their respective roles patient pathway is limited. Therefore, aim this qualitative study was to document these perceptions. Methods A multidisciplinary team that included researchers constructed a semi‐structured interview guide colorectal by professionals. Interviews were conducted with from two French hospitals manage patients cancer. Then, interviews fully transcribed...
Trop souvent, les notices d’information proposées dans le cadre de recherches cliniques se réduisent à des documents réglementaires difficilement compréhensibles. Pourtant, personnes concernées doivent avoir accès une information transparente et loyale. Ces considérations ont motivé la création d’un groupe travail pluridisciplinaire, piloté par Collège relecteurs l’Inserm, associant acteurs impliqués l’élaboration, l’évaluation l’utilisation ces d’information. Un ensemble textes,...
Familial disclosure of genetic information is an important, long-standing ethical issue that still gives rise to much debate. In France, recent legislation has created innovative and unprecedented procedure allows healthcare professionals (HCPs), under certain conditions, disclose relevant relatives a person carrying deleterious mutation. This article will analyse how HCPs in two medical genetics clinics have reacted these new legal provisions show their reticence inform the patients’ on...
Concerns are emerging about the protection of individuals who take part in genetic research involving biobanks. We used several items a questionnaire sent to 48 French ethics committees (RECs) investigate means by which they evaluate constitution and use biobanks, elements on conclusions were based. Most RECs felt should biobanks protocols, but not all did so practice. Harmonization competence for evaluating is required, particularly concerning information, consent, duration sample...
La maternité pour autrui est interdite par la loi française. Alors que Cour de cassation, le 17 décembre 2008, vient refuser transcription sur les registres français d’état civil des actes naissance américains d’enfants nés d’une mère porteuse en Californie, certains réclament une intervention du législateur légaliser pratique. Une telle revendication pourtant loin faire l’unanimité. Deux rapports successifs instances législatives expriment ces avis opposés : celui d’un groupe travail Sénat...
Le séquençage du génome humain est de plus en utilisé oncologie pédiatrique afin diagnostiquer, sélectionner un traitement ciblé ou suivi adapté d’identifier une transmission héréditaire. Les investigations génétiques soulèvent des enjeux éthiques et juridiques qui se cristallisent autour consentement enfants, mais aussi leurs parents. Il s’agirait notamment s’assurer que la décision prise connaissance cause, c’est-à-dire ayant compris les résultats attendus incidences pour soi-même ses...