A5010483495- Plant Virus Research Studies
- Fungal Plant Pathogen Control
- Plant-Microbe Interactions and Immunity
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Synthesis and Characterization of Heterocyclic Compounds
- Insect and Pesticide Research
- Plant Pathogenic Bacteria Studies
- Organophosphorus compounds synthesis
- Quinazolinone synthesis and applications
- Crystallization and Solubility Studies
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- X-ray Diffraction in Crystallography
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Plant Disease Resistance and Genetics
- Insect-Plant Interactions and Control
- Catalytic Cross-Coupling Reactions
- Catalytic C–H Functionalization Methods
- Synthetic Organic Chemistry Methods
- Asymmetric Synthesis and Catalysis
- Analytical Chemistry and Chromatography
- Asymmetric Hydrogenation and Catalysis
- Plant Pathogens and Fungal Diseases
- Chemical Synthesis and Analysis
- Insect Pest Control Strategies
Guizhou University
2016-2025
Ministry of Education of the People's Republic of China
2007-2024
Guizhou Institute of Plant Protection
2023
Bioengineering Center
2014-2020
University of Nottingham Ningbo China
2017
Nanyang Technological University
2013-2016
Jilin University
2016
University of South Carolina
2014
Zunyi Medical University
2013
Nanjing University
2009
A series of new sulfone compounds containing the 1,3,4-oxadiazole moiety were designed and synthesized. Their structures identified by 1H 13C nuclear magnetic resonance elemental analyses. Antibacterial bioassays indicated that most exhibited promising in vitro antibacterial bioactivities against tobacco bacterial wilt at 200 μg/mL. The relationship between structure activity was also discussed. Among title compounds, 5′c, 5′h, 5′i, 5′j could inhibit mycelia growth Ralstonia solanacearum...
Ionic liquids (ILs) which are made up of cationic and anionic components can be designed to possess a definite set properties. In this context, the term "designer solvents" has been used demonstrate potential these environment-friendly ionic in chemical reactions. Since able dissolve several transition metal complexes, they have often employed recent times catalytic reactions enhance reaction rates selectivities. The concept "immobilized" derived from supported liquid phase catalysts;...
Catalytic transfer hydrogenation (CTH) reactions are efficient transformation routes to upgrade biobased chemicals. Herein, we report a facile and template-free route synthesize series of heterogeneous nitrogen-containing alkyltriphosphonate–metal hybrids with enhancive Lewis acid base sites, their catalytic activity in converting biomass-derived carbonyl compounds corresponding alcohols 2-propanol. Particularly, quantitative yield furfuryl alcohol (FFA) was obtained from furfural (FUR) over...
Target compounds 4a−n were obtained by the reaction of 1-substituted phenyl-3-methyl-5-substituted phenylthio-4-pyrazolaldoximes (3) with chloromethylated heterocyclic (ClCH2-R3) under reflux conditions in ethanol. Subsequently, oxidation 4a−e KMnO4 HOAc at room temperature afforded eight new compounds, 5a−h. The synthesized characterized physical constants, and structures title confirmed IR, 1H NMR, 13C elemental analysis. bioassay revealed that possessed antiviral activities. It was found...
Aryl aldehyde activation: Oxidative activation of 2-methylindole-3-carboxaldehyde (I) through N-heterocyclic carbene (NHC) organocatalysis generates heterocyclic ortho-quinodimethane (II) as a key intermediate. This intermediate then undergoes formal [4+2] cycloaddition with trifluoromethyl ketones or isatins to form polycyclic lactones containing quaternary carbon center.
Starting from benzaldehyde 1, the title compounds 8 were synthesized in six steps. Benzaldehyde1 was reacted with ammonium hydroxide, and resulting imine then treated dialkyl phosphite 3 to give N-(arylmethylene)-1-amino-1-aryl methylphosphonates 4. Phosphonates 4 easily hydrolyzed 1-amino-1-aryl-methylphosphonates 6, which on treatment triethylamine, carbon disulfide, phosphorus oxychloride provided 7. Target prepared by reaction of 7 substituted chiral amine. The structures clearly...
This study aimed to synthesize some new sulfone derivatives containing a 1,3,4-oxadiazole moiety and investigate their in vitro antibacterial activities against Xanthomonas oryzae pv. ( Xoo) axonopodis citri Xac), the pathogens of rice bacterial leaf blight citrus canker, respectively, by performing turbidimeter tests. Antibacterial bioassay results showed that compound 6d revealed excellent bioactivities Xoo Xac, with 50% effective concentration (EC50) values 0.17 1.98 μg/mL, compared...
A carbene-catalyzed desymmetrization of prochiral bisphenol compounds bearing remote P-stereogenic centers is disclosed. The catalytic reactions can be performed on gram scales with 1 mol % N-heterocyclic carbene (NHC) catalyst, providing efficient access to enantiomerically enriched phosphinates. chiral phosphinates prepared our method find widespread applications as asymmetric organic catalysts and ligands.
Abstract BACKGROUND: Pyrazole and hydrazone derivatives possess good insecticidal activities; their substructural units are widely used in pesticide design. In an effort to discover new molecules with activities, a series of pyrazole amide containing substructures were synthesised bioassayed. RESULTS: Bioassays demonstrated that some the title compounds exhibited notable control Plutella xylostella (Linnaeus), Helicoverpa armigera (Hübner), Culex pipiens pallens, Laphygma exigua Spodoptera...
Twenty-seven novel (E)-3-[2-arylideneaminoethyl]-2-[4-(trifluoromethoxy)anilino]-4(3H)-quinazolinone derivatives were synthesized by reacting various aromatic aldehydes with intermediate 6. The target compounds characterized (1)H NMR, (3)C IR, and elemental analysis. Bioassay results revealed that some of the have strong antifungal activities against six fungi ( Gibberella zeae , Fusarium oxysporum Clematis mandshurica Paralepetopsis sasakii Phytophthora infestans Sclerotinia sclerotiorum )...
Abstract A convergent, organocatalytic asymmetric aminomethylation of α,β‐unsaturated aldehydes by N‐heterocyclic carbene (NHC) and (in situ generated) Brønsted acid cooperative catalysis is disclosed. The catalytically generated conjugated from the base plays dual roles in promoting formation azolium enolate intermediate, formaldehyde‐derived iminium ion (as an electrophilic reactant), methanol a nucleophilic reactant). This redox‐neutral strategy suitable for scalable synthesis...
A β-cyclodextrin-SO<sub>3</sub>H-assisted, convenient and efficient strategy for the preparation of 2,3-dihydroquinazolin-4(1<italic>H</italic>)-one derivatives in aqueous media is presented.
An N-heterocyclic carbene (NHC) catalyzed domino reaction triggered by a δ-LUMO activation of α,β-γ,δ-diunsaturated enal has been developed for the formal [4 + 2] construction multisubstituted arenes and 3-ylidenephthalide. These two products, formed in highly chemo- regioselective manner, were obtained via different catalytic pathways due to simple change substrate. The remote δ-carbon unsaturated aldehydes expands synthetic potentials NHC organocatalysis.