A5086814441- X-ray Diffraction in Crystallography
- Origins and Evolution of Life
- Crystallization and Solubility Studies
- Catalytic C–H Functionalization Methods
- Protein Structure and Dynamics
- Photoreceptor and optogenetics research
- Radical Photochemical Reactions
- Oxidative Organic Chemistry Reactions
- Molecular spectroscopy and chirality
- Chromatography in Natural Products
- Fluorine in Organic Chemistry
- Analytical Chemistry and Chromatography
- Crystallography and molecular interactions
- Surface Chemistry and Catalysis
- Organophosphorus compounds synthesis
- Synthesis and characterization of novel inorganic/organometallic compounds
- Mass Spectrometry Techniques and Applications
- Enzyme Catalysis and Immobilization
- Chemical synthesis and alkaloids
Ludwig-Maximilians-Universität München
2019-2025
<title>Abstract</title> Nonlinear effects in chemical reactions, <sup>1</sup> coupled with amplifying catalysis, give rise to remarkable phenomena such as spontaneous symmetry breaking,<sup>2</sup> a process associated the emergence of homochiral world at origin life.<sup>3,4</sup> Soai's asymmetric autocatalysis<sup>5</sup> serves prototypical reaction that intrinsically integrates these properties. In this reaction, enantiomeric excess added product alcohol is not only preserved during...
Abstract To understand chiral symmetry breaking on the molecular level, we developed a method to efficiently investigate reaction kinetics of single molecules. The model systems include autocatalysis as well cascade gain further insight into prebiotic origin homochirality. simulated reactions start with substrate and only catalyst molecule, occurrence was examined for its degree dependence randomness. results demonstrate that interlocking processes, which e.g., form catalysts, autocatalytic...
Alkylations of simple electron‐rich heterocompounds deliver valuable target structures in bioorganic and medicinal chemistry. Herein, we present a straightforward photosensitizer free approach for the photoinduced C–C coupling unsaturated with alkyl bromides using 405 nm 365 irradiation. Comprehensive mechanistic studies indicate involvement 2,6‐lutidine formation non‐covalently bound intermediate to which function is attributed. UV/Vis spectra reveal bathochromic shifted band when...
(Fluoromethyl)triphenylphosphonium iodide has been prepared in a simple and high yield synthesis. The salt was characterized by vibrational, NMR spectroscopy single‐crystal X‐ray structure analysis. crystallizes an orthorhombic space group Pna 2 1 with four formula units the unit cell. experimental data are discussed together quantum chemically calculated values. title compound is first example of phosphonium containing P‐CH F moiety. Hydrogen bonding crystal fluoromethyl discussed.
ConspectusLife as we know it is built on complex and perfectly interlocking processes that have evolved over millions of years through evolutionary optimization processes. The emergence life from nonliving matter the evolution such highly efficient systems therefore constitute an enormous synthetic chemistry challenge. Advances in supramolecular are opening new perspectives provide insights into living self-sustaining reaction networks precursors for life. However, ab initio synthesis a...