A5089849771- Advanced Radiotherapy Techniques
- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Advances in Oncology and Radiotherapy
- COVID-19 and healthcare impacts
- Radiation Dose and Imaging
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Treatments and Mutations
- Radiation Therapy and Dosimetry
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal Cancer Surgical Treatments
- Cancer Immunotherapy and Biomarkers
- Pancreatic and Hepatic Oncology Research
- Lung Cancer Research Studies
- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Cancer survivorship and care
Ospedale Generale Regionale Francesco Miulli
2021-2024
Universidad Autónoma de Bucaramanga
2023-2024
University Research Co (United States)
2024
Libera Università Maria SS. Assunta
2024
Ospedale Pediatrico Giovanni XXIII
2020
University of Bari Aldo Moro
2018
Istituto Tumori Bari
2015-2016
Background/Objectives: Hypofractionated radiation therapy (Hypo-RT) schedules may offer radiobiological, patient convenience, and healthcare resource advantages over standard fractionated (S-RT) for glioblastoma (GBM). Additionally, simulated integrated boost (SIB) Hypo-RT is proven to be an effective safe treatment. We report on our experience regarding progression-free survival (PFS), overall (OS), RT-related toxicities in GBM patients treated with S-RT. Methods: Patients IDH-wildtype...
Hemangiopericytoma (HPC) is an extremely rare hypervascular tumor of mesenchymal lineage. It tends to recur and develop distant metastases even many years after primary surgical resection. The management recurrent metastatic disease not always so well defined. A complete resection does eliminate the high risk local recurrences that occur in central nervous system, often same bed. However, treatment with adjuvant radiotherapy cases remains controversial. Because its rarity, there no standard...
Glioblastoma (GBM) is a very poor-prognosis brain tumor. To date, maximal excision followed by radiochemotherapy, in 30 fractions, the standard approach. Limited data are present literature about hypofractionated radiotherapy (hypo-RT) GBM poor prognosis patients. Thus, this retrospective study was conducted to evaluate efficacy and toxicity of hypo-RT with simultaneous integrated boost (SIB) association temozolomide (TMZ) patient setting.Poor-prognosis patients underwent surgery (complete,...
Abstract Aims Stereotactic arrhythmia radioablation (STAR) is a novel therapeutic approach for cardiac arrhythmias. The aim of this trial to investigate the feasibility STAR treatment paroxysmal atrial fibrillation (AF) in elderly patients. Methods and results Inclusion criteria were age >70 years, symptomatic AF, antiarrhythmic drugs failure, or intolerance. All patients underwent 4D computed tomography simulation. clinical target volume was identified area around pulmonary veins...
Treatment approach for elderly patients with atrial fibrillation (AF) is difficult. The present prospective phase-II trial evaluated LINAC-based stereotactic arrhythmia radioablation safety in this population. reported data of the first 5 worldwide, showed no side effects, absence AF episodes and without antiarrhythmic drugs.ClinicalTrials.gov, identifier: NCT04575662.
Postoperative radiotherapy after breast-conserving surgery (BCS) is the standard in management of breast cancer. The optimal timing for starting postoperative radiation therapy has not yet been well defined. In this study, we aimed to evaluate if time interval between BCS and related incidence local distant relapse women with early node-negative cancer receiving chemotherapy.We retrospectively analyzed clinical data concerning 615 treated from 1984 2010, divided into three groups according...
Purpose. For recurrent high-grade gliomas (HGG), no standard therapeutic approach has been reported; thus, surgery, chemotherapy, and re-irradiation (re-RT) may all be proposed. The aim of the study was to evaluate safety efficacy re-RT by radiosurgery or fractionated stereotactic radiotherapy (SRS/FSRT) in association chemotherapy patients with HGG. Material/Methods: All histological diagnosis HGG that suffered disease diagnosed magnetic resonance imaging (MRI), according Response...
A 71-year-old male ex-smoker presented in October 2021 to our department with a brain and bone metastatic adenocarcinoma NSCLC. PDL1, ROS, EGFR, ALK were negative. He underwent stereotactic radiotherapy for metastases. In November 2021, he started chemotherapy (CHT) regimen cisplatin (75 mg/m2 every 21 days) pemetrexed (500 days), ICI Atezolizumab (1200 mg days). July 2022, RT the lung tumor mediastinal nodal was performed total dose of 45 Gy 15 fractions. continued immunotherapy until...
To test inter-fraction reproducibility, intrafraction stability, technician aspects, and patient/physician's comfort of a dedicated immobilization solution for Brain Linac-based radiation therapy (RT).A pitch-enabled head positioner with an open-face mask were used and, to evaluate inter- variations, 1-3 Cone-Beam Computed Tomography (CBCT) performed. Surface Guided Radiation Therapy (SGRT) was variations at 3 time points: initial (i), final (f), monitoring (m) (before, end, during RT). Data...
Purpose: Approaching treatment for elderly patients with atrial fibrillation is difficult. A prospective phase II trial evaluating LINAC-based stereotactic arrhythmia radioablation (STAR) safety in this population started 2021. Dosimetric and planning data were reported. Materials Methods: vac-lock bag was used immobilization the supine position a computed tomography (CT, 1 mm) performed. The clinical target volume (CTV) defined as area around pulmonary veins. An internal (ITV) added to CTV...
In our radiation departments, all patients received psycho-oncological support during RT and follow-up. Based on the latter, aim of this retrospective analysis was to evaluate role tele-visits in-person psychological for cancer after RT, report a descriptive pointing out needs psychosocial intervention in department treatment.According institutional care management, receiving were prospectively enrolled receive charge-free assessment their cognitive, emotional physical states treatment. For...
Abstract Introduction A growing body of evidence suggests that metabolic syndrome is associated with endocrine disorders, including thyroid dysfunction. Thyroid dysfunction in patients may further increase the risk cardiovascular disease, thus increasing mortality. This study was conducted to assess function and its relationship components syndrome. Methods cross-sectional carried out among 170 geriatric patients. Anthropometric measurements (height, weight, waist circumference) blood...
Abstract Background We present a case of 51‐year‐old man affected by Rosai–Dorfman disease with multiple disseminated intraparenchymal and single spinal cord localization, presenting dysphasia paraparesis. Case Presentation The patient elected to receive medical steroidal therapy two radiotherapy cycles. Steroids allowed initial regression some lesions, while constituted an optimal maintenance treatment. At 6‐year follow up, the did not develop any new neurological damage in respect...
Errors and incidents may occur at any point within radiotherapy (RT). The aim of the present retrospective analysis is to evaluate impact a customized ARIA Visual Care Path (VCP) on quality assurance (QA) for RT process. VCP was implemented in June 2019. following tasks were independently verified (by independent checks from radiation oncologists, medical physics, therapists): simulation, treatment planning, start verification, completion. A 105 random unselected patients performed, 945...
<title>Abstract</title> Increased background parenchymal enhancement (BPE) is an imaging biomarker of higher risk BC. The aim this prospective study was to evaluate the distribution BPE patterns and possible onset BC in long-term HL survivors treated with chemotherapy RT compare them age-matched women BRCA mutation carriers without a history cancer. 62 women, for at least 15 years consecutive same age carriers, underwent screening dynamic contrast magnetic resonance imaging. comparable two...