- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Heart Rate Variability and Autonomic Control
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Cardiovascular Health and Disease Prevention
- Cerebrovascular and Carotid Artery Diseases
- Pleural and Pulmonary Diseases
- Cardiac Health and Mental Health
- Blood Pressure and Hypertension Studies
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiovascular Disease and Adiposity
- Cardiac Ischemia and Reperfusion
- Dam Engineering and Safety
- Pain Management and Treatment
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Infective Endocarditis Diagnosis and Management
- Fluid Dynamics Simulations and Interactions
- Geotechnical Engineering and Underground Structures
Ospedale Generale Regionale Francesco Miulli
2015-2025
University of Foggia
2021-2024
Ospedale A. Perrino
2023
Fondazione Poliambulanza Istituto Ospedaliero
2019
Policlinico Umberto I
2018
Sapienza University of Rome
2018
Università Cattolica del Sacro Cuore
2007-2016
Hospital Posadas
2016
University of the Sacred Heart
2010-2016
University of Pavia
2011
Impaired flow-mediated dilation (FMD) is associated with cardiovascular risk factors and provides prognostic information. Despite the noninvasive nature of this technique, a major limitation to its widespread use low reproducibility. The aim study was evaluate impact methodological standardization among different investigation sites on brachial artery FMD reproducibility.Seven Italian centers recruited 135 healthy volunteers, aged 20-60 years. assessed by high-resolution ultrasound equipped...
Background: Pulsed-field ablation (PFA) is a tissue-selective, nonthermal cardiac modality. A novel PFA system consisted of multichannel irreversible electroporation generator and multielectrode circular catheter has been developed for ablation. To understand the progression immediate impacts PFA, this study evaluated subchronic (7±3 day) chronic (30±3 safety performance when simulating pulmonary vein superior vena cava isolation in porcine beating heart model. Methods: Ten swine models were...
:This paper presents a general semi-analytic approach for modeling solid boundaries in the SPH method: are here considered as material continuum with suitable distribution of velocity and pressure; their contributions to each term mass momentum equations can be expressed terms integral extended part sphere influence particle delimited by boundary surface. Analytical details reference slightly compressible viscous Newtonian fluid three dimensions given. The validity method is checked...
The number of cardiovascular implantable electronic devices has increased progressively, leading to an need for transvenous lead extraction (TLE) due device infections. Previous studies described 'ghost' as a post-removal, new, tubular, mobile mass detected by echocardiography following the lead's intracardiac route in right-sided heart chambers, associated with diagnosis cardiac device-related infective endocarditis. We aimed analyse association between 'ghosts' assessed transesophageal...
The RADIANCE first-in-man study evaluated acute (3-month) safety and design concept in terms of utility a new multi-electrode radiofrequency (RF) balloon catheter (HELIOSTAR, Biosense Webster) to achieve pulmonary vein isolation (PVI). After conclusion, subset patients was followed up 12 months.Patients with drug refractory paroxysmal atrial fibrillation were enrolled. Neurological assessment, cardiac cerebral magnetic resonance imagings performed pre post procedure. Ablation delivered at 15...
Background Cardioneuroablation (CNA) is a new approach to treat reflex syncope and functional bradyarrhytmias caused by autonomic imbalance. We report our experience using CNA. Method From September 2022 July 2023, we took care of 21 patients (mean age 42 ± years; 62% male) affected or bradyarrhythmias. All underwent CNA under conscious sedation targeting the superior and/or inferior paraseptal ganglionated plexus (GPs). Results Nine were vasovagal (VVS) twelve In 3 cases (14%) ablation was...
The paper is concerned with the calculation of electrostatic potentials and fields for realistic engineering problems. Three computational methods, charge-simulation method, finite-element method Monte Carlo have been programmed practical use. To test their accuracy, results obtained a set trial problems are compared. Examples also given that illustrate particular capabilities each different advantages disadvantages discussed.
Background The causes of coronary microvascular dysfunction (CMVD) in patients with cardiac syndrome X (CSX) are largely unknown. Common cardiovascular risk factors (CVRFs) and increased markers inflammation have been associated CMVD some studies, but their role determining CSX remains poorly known. Methods results We studied 71 (56 ± 9 years, 23 men) 20 healthy volunteers (52 7 nine men). Using transthoracic Doppler echocardiography, vasodilator function was assessed the left anterior...
Recent data suggest that vagus nerve stimulation (VNS) can inhibit cytokine release by inflammatory cells. Accordingly, an association between impaired cardiac parasympathetic function, as assessed heart rate variability (HRV), and increased markers of inflammation has recently been reported. In this study we the effect direct left VNS on HRV in patients with refractory epilepsy.A 24-hour electrocardiogram Holter recording was performed both at baseline after 3 months 8 (age 32 +/- 24 years,...
Abstract Introduction Pulmonary vein (PV) isolation is the cornerstone of catheter ablation in patients with atrial fibrillation (AF). Surround flow and contact force (CF) measurement capabilities might enhance procedure efficacy safety. We report on safety midterm a novel for PV AF. Methods results Two hundred thirty‐three consecutive (57 ± 11 years, 76% males, 51% structural heart disease), referred paroxysmal (157) or persistent (76) AF, underwent by surround CF capability four centers....
Awareness of radiation exposure risks associated to interventional cardiology procedures is growing. The availability new technologies in electrophysiology laboratories has reduced fluoroscopy usage during arrhythmias ablations. aim this study was describe with and without X-Rays assess feasibility, safety, short-term efficacy zero intervention a high-volume center oriented keep ionizing as low reasonably achievable.
Treatment approach for elderly patients with atrial fibrillation (AF) is difficult. The present prospective phase-II trial evaluated LINAC-based stereotactic arrhythmia radioablation safety in this population. reported data of the first 5 worldwide, showed no side effects, absence AF episodes and without antiarrhythmic drugs.ClinicalTrials.gov, identifier: NCT04575662.