A5034980807- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Effects of Exercise
- Cardiac Imaging and Diagnostics
- Viral Infections and Immunology Research
- Heart Rate Variability and Autonomic Control
- ECG Monitoring and Analysis
- Cardiac Structural Anomalies and Repair
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiomyopathy and Myosin Studies
- Coronary Interventions and Diagnostics
- Chemotherapy-induced cardiotoxicity and mitigation
- Pericarditis and Cardiac Tamponade
- Cardiac Valve Diseases and Treatments
- Blood Pressure and Hypertension Studies
- Peripheral Artery Disease Management
- Cardiovascular Function and Risk Factors
- Cardiac Health and Mental Health
- Venous Thromboembolism Diagnosis and Management
- Acute Myocardial Infarction Research
- Cardiovascular Issues in Pregnancy
- Cardiovascular Health and Disease Prevention
- Obstructive Sleep Apnea Research
Università Cattolica del Sacro Cuore
2010-2024
Agostino Gemelli University Polyclinic
2019-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2024
Osaka University
2013
University of the Sacred Heart
2010-2012
Background The causes of coronary microvascular dysfunction (CMVD) in patients with cardiac syndrome X (CSX) are largely unknown. Common cardiovascular risk factors (CVRFs) and increased markers inflammation have been associated CMVD some studies, but their role determining CSX remains poorly known. Methods results We studied 71 (56 ± 9 years, 23 men) 20 healthy volunteers (52 7 nine men). Using transthoracic Doppler echocardiography, vasodilator function was assessed the left anterior...
<b><i>Objectives:</i></b> The aim of our study was to assess the prognostic value heart rate variability (HRV) in ST-segment elevation acute myocardial infarction (STEMI) patients treated by percutaneous transluminal coronary angioplasty (PTCA) and optimal medical therapy. <b><i>Methods:</i></b> We enrolled 182 consecutive with a first STEMI (59.1 ± 11 years; 82.4% men) primary PTCA. HRV assessed on 24-hour Holter ECG recordings before...
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is associated with an increased risk of sudden cardiac death (SCD). Risk stratification ARVC/D patients, however, remains unresolved issue. In this study we investigated whether heart rate variability (HRV) can be helpful in identifying patients arrhythmic events.We studied 30 consecutive (17 males; 45.4 ± 18 years) ARVC/D, diagnosed according to guideline criteria; 15 (50%) had received implantable cardioverter defibrillator...
Low left ventricular ejection fraction (LVEF) is the main indication of implantable cardioverter defibrillators (ICD) in patients with dilated cardiomyopathy (DCM) for primary prevention sudden cardiac death, but ICD therapy at follow-up occurs a minority patients. We investigated whether heart rate variability (HRV) may improve risk stratification DCM patients.We studied 42 (age 67.3 ± 3.5; 37 males) who had undergone implant either idiopathic or ischaemic (LVEF <40%) 34.6 19.7 months prior...
Aims To investigate predictors of the occurrence subacute ventricular arrhythmias (VAs), defined as any VAs presenting after 48 h from admission in patients with Takotsubo Syndrome (TTS), and to evaluate related in-hospital mortality. Methods This is a retrospective single-center study enrolling admitted between 2012 2017 TTS according International diagnostic criteria. Data collection included ECG on at h, telemetry monitoring transthoracic echocardiogram. Results We enrolled 93 patients;...
Background: Circulating endothelial progenitor cells (EPCs) might limit dysfunction in patients with microvascular angina (MVA). Endothelial colony-forming (ECFCs; displaying the CD34+/KDR+/CD45– phenotype) are currently regarded as true EPCs. The aim of this study was to evaluate exercise-induced ECFC mobilization and platelet reactivity MVA or obstructive coronary artery disease (CAD). Methods Results: Exercise stress test (EST) performed 20 patients, CAD controls. Platelet assessed before...
Abstract Background Pericarditis, along with myocarditis, is being increasingly reported after the coronavirus disease 2019 (COVID-19) vaccine, but best treatment strategy in this specific setting still unclear. Case summary We report a case of acute pericarditis second dose mRNA COVID-19 vaccine recurrence large pericardial effusion previous pericardiocentesis and anti-inflammatory drugs tapering. The patient was successfully treated recombinant interleukin-1 receptor antagonist anakinra,...
Microvolt T-wave alternans (TWA) predicts arrhythmic risk in patients with ischaemic heart disease (IHD). While TWA has widely been assessed by the spectral method, it poorly characterized healthy people as well IHD modified moving average (MMA) method.We enrolled 729 consecutive subjects, referred for exercise stress test (EST). was MMA considering all 12 electrocardiogram (ECG) leads (TWA_tot) or 6 ECG pre-cordial only (TWA_prec). Patients were divided into five groups: (i) no history of...
Aims Microvolt T-wave alternans (MTWA) has been found to predict fatal events in patients with coronary artery disease (CAD). In a previous study, we that MTWA values are higher CAD, compared apparently healthy individuals. this assessed the relation between CAD and diagnosis based on angiography results. Methods We studied 98 consecutive undergoing for suspected CAD. All underwent maximal exercise stress test (EST), was measured precordial ECG leads. Patients were divided into three groups:...
Unrecognized incomplete pulmonary vein (PV) isolation during the index procedure, can be a major cause of clinical recurrences atrial fibrillation (AF) after cryoballoon (CB) ablation. We aimed to characterize extension lesions produced by CB ablation and assess value using an ultra-high resolution electroanatomic mapping (UHDM) system detect lesions.Twenty-nine consecutive patients from CHARISMA registry undergoing AF at four Italian centers were prospectively evaluated. The Rhythmia™...
To assess the characteristics and determinants of heart rate turbulence (HRT) in individuals without any apparent disease patients with coronary artery (CAD). Heart parameters, onset (TO), slope (TS) were calculated on 24 h electrocardiogram recordings 209 (group 1) 157 CAD 2). In group 1, only age independently predicted abnormal TO (≥0%) [odds ratio (OR), 1.05; P<0.001], while predictors TS (≤2.5 ms/RR) (OR, 0.85; P < 0.001) hypertension 0.19; = 0.028). 2 patients, 1.03; 0.038), 0.90; left...
Background: Drug-eluting stents (DES) have reduced restenosis following percutaneous coronary intervention (PCI), but they seem to be associated with increased endothelial dysfunction compared bare metal (BMS). No data are available about the prognostic value of exercise stress test (EST) in PCI patients DES era. Methods and Results: The 160 artery disease (CAD) who underwent either BMS (n=86) or (n=74) were studied. EST was performed 1 month after PCI. had a higher rate positive (49% vs...
Background. Adults with congenital heart disease (ACHD) are often affected by cardiac arrhythmias requiring catheter ablation. Catheter ablation in this setting represents the treatment of choice but is flawed frequent recurrencies. Predictors arrhythmia relapse have been identified, role fibrosis has not investigated. The aim study was to determine extension fibrosis, detected electroanatomical mapping, predicting recurrencies after ACHD. Materials and Methods. Consecutive patients atrial...
Introduction: Although catheter ablation is the current gold standard treatment for refractory ventricular arrhythmias, sometimes its efficacy not optimal and it's associated with high risks of procedural complication death. Stereotactic arrhythmia radioablation (STAR) increasingly being adopted such clinical presentation, considering safety. Case Presentation: We do report our experience managing a case volume left ventricle tachycardia in advanced heart failure patient, by delivering...
Atrioventricular (AV) conduction disturbances requiring permanent pacemaker implantation (PPI) are a common complication after transcatheter aortic valve (TAVI). However, significant proportion of patients might recover AV at follow-up.
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