A5006966400- Mental Health Treatment and Access
- Mental Health and Psychiatry
- Primary Care and Health Outcomes
- Health, psychology, and well-being
- Psychosomatic Disorders and Their Treatments
- Migration, Health and Trauma
- Health disparities and outcomes
- Palliative Care and End-of-Life Issues
- Empathy and Medical Education
- Child and Adolescent Psychosocial and Emotional Development
- Mental Health and Patient Involvement
- Schizophrenia research and treatment
- Chronic Disease Management Strategies
- Treatment of Major Depression
- Health Policy Implementation Science
- Health Systems, Economic Evaluations, Quality of Life
- Patient-Provider Communication in Healthcare
- Mental Health Research Topics
- Interprofessional Education and Collaboration
- Employment and Welfare Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cardiac Health and Mental Health
- Geriatric Care and Nursing Homes
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Grief, Bereavement, and Mental Health
University of Liverpool
2016-2025
Liverpool John Moores University
2024
University Research Co (United States)
2024
The University of Melbourne
2010-2022
Centre for Mental Health
2022
Liverpool Hospital
2021
Institute of Population and Public Health
2020
World Organisation of Family Doctors
2020
Institute of Psychology, Chinese Academy of Sciences
2016-2019
Primary Health Care
2008-2017
The past decade has seen considerable interest in the development and evaluation of complex interventions to improve health. Such can only have a significant impact on health care if they are shown be effective when tested, capable being widely implemented normalised into routine practice. To date, there is still problematic gap between research implementation. Normalisation Process Theory (NPT) addresses factors needed for successful implementation integration work (normalisation). In this...
Theories are important tools in the social and natural sciences. The methods by which they derived rarely described discussed. Normalization Process Theory explains how new technologies, ways of acting, working become routinely embedded everyday practice, has applications study implementation processes. This paper describes process it was built. Between 1998 2008, we developed a theory. We set empirical generalizations from analysis data collected qualitative studies healthcare work...
Abstract Background The Normalization Process Model is a theoretical model that assists in explaining the processes by which complex interventions become routinely embedded health care practice. It offers framework for process evaluation and also comparative studies of interventions. focuses on factors promote or inhibit routine embedding Methods A formal theory structure used to define model, its internal causal relations mechanisms. broken down show it consistent adequate generating...
Background This is the first report on epidemiology of depressive disorders from European Outcome Depression International Network (ODIN) study. Aims To assess prevalence in randomly selected samples general population five countries. Method The study was designed as a cross-sectional two-phase community using Beck Inventory during Phase 1, and Schedule for Clinical Assessment Neuropsychiatry 2. Results An analysis combined sample ( n =8.764) gave an overall 8.56% (95% Cl 7.05–10.37)....
The Global Burden of Disease study conducted between 1990 and 2016, based on a global 195 countries territories, identified Parkinson disease (PD) as the fastest growing neurological disorder when measured using death disability. Most people affected by PD live in low- middle-income (LMICs) experience large inequalities access to care essential medicines. This Special Communication describes 6 actions steps that are urgently needed address disparities PD. adoption 73rd World Health Assembly...
<b>Objective</b> To determine if general practitioner rates of antidepressant drug prescribing and referrals to specialist services for depression vary in line with patients’ scores on severity questionnaires. <b>Design</b> Analysis anonymised medical record data. <b>Setting</b> 38 practices three sites—Southampton, Liverpool, Norfolk. <b>Data reviewed</b> Records 2294 patients assessed questionnaires between April 2006 March 2007 inclusive. <b>Main outcome measures</b> Rates antidepressants...
<h3>Abstract</h3> <b>Objectives:</b> To determine the acceptability of two psychological interventions for depressed adults in community and their effect on caseness, symptoms, subjective function. <b>Design:</b> A pragmatic multicentre randomised controlled trial, stratified by centre. <b>Setting:</b> Nine urban rural communities Finland, Republic Ireland, Norway, Spain, United Kingdom. <b>Participants:</b> 452 participants aged 18 to 65, identified through a survey with depressive or...
<b>Objective</b> To gain understanding of general practitioners’ and patients’ opinions the routine introduction standardised measures severity depression through UK practice quality outcomes framework. <b>Design</b> Semistructured qualitative interview study, with purposive sampling constant comparative analysis. <b>Participants</b> 34 practitioners 24 patients. <b>Setting</b> 38 practices in three sites England: Southampton, Liverpool, Norfolk. <b>Results</b> Patients generally favoured...
<h3>Abstract</h3> <b>Objectives</b> : To assess the extent to which outcome of depression among primary care attenders may be affected by medical diagnosis or feedback questionnaire results in unrecognised cases. <b>Design</b> Prospective 12 month study including a randomised controlled trial effects disclosure, with data on status and clinical management collected interview. <b>Setting</b> Two group practices north Liverpool. <b>Subjects</b> 1099/1444 (76%) consecutive adult completed Beck...
Mental health problems are common in primary care, particularly anxiety and depression. This study aims to estimate the prevalence of mental disorders their associations with socio-demographic characteristics care Brazil (Family Health Strategy). It involved a multicenter cross-sectional patients from Rio de Janeiro, São Paulo, Fortaleza (Ceará State) Porto Alegre (Rio Grande do Sul State), assessed using General Questionnaire (GHQ-12) Hospital Anxiety Depression Scale (HAD). The rate were...
The Normalization Process Model is a conceptual tool intended to assist in understanding the factors that affect implementation processes clinical trials and other evaluations of complex interventions. It focuses on ways interventions shaped by problems workability integration. In this paper model applied two different trials: (i) delivery problem solving therapies for psychosocial distress, (ii) nurse-led clinics heart failure treatment primary care. Application shows how process need focus...
The coinhibitory receptor programmed death-1 (PD-1) maintains immune homeostasis by negatively regulating T cell function and survival. Blockade of PD-1 increases the severity graft-versus-host disease (GVHD), but interplay between inhibition metabolism is not well studied. We found that both murine human alloreactive cells concomitantly upregulated expression increased levels reactive oxygen species (ROS) following allogeneic bone marrow transplantation. This...
<h3>PURPOSE</h3> Indicators of prognosis should be considered to fully inform clinical decision making in the treatment depression. This study examines whether self-rated health predicts long-term depression outcomes primary care. <h3>METHODS</h3> Our analysis was based on first 5 years a prospective 10-year cohort underway since January 2005 conducted 30 randomly selected Australian care practices. Participants were 789 adult patients with history depressive symptoms. Main outcome measures...
Summary Objective To explore the individual experiences of those who had experienced death a parent(s) before age 18, and investigate how such were perceived to impact on adult life. Design An exploratory qualitative design using written (n = 5) oral (n= 28) narratives narrative analysis was adopted 33 adults (7 men 26 women) parental during childhood. Setting UK Participants Individuals living in North West England lost 18. Main outcome measures Views bereaved parent 18 loss Results While...
In order to provide effective primary care for refugees and develop interventions tailored them, we must know their needs. Little is known of the health needs experiences recently arrived other migrants throughout journey through Europe. We aimed gain insight into needs, barriers in access wishes regarding care. spring 2016, conducted a qualitative, comparative case study seven EU countries centre first arrival, two transit centres, intermediate-stay centres longer-stay using Participatory...