- Health Systems, Economic Evaluations, Quality of Life
- Global Cancer Incidence and Screening
- Cancer survivorship and care
- Patient-Provider Communication in Healthcare
- Palliative Care and End-of-Life Issues
- Climate Change Communication and Perception
- Musculoskeletal pain and rehabilitation
- Cervical Cancer and HPV Research
- Childhood Cancer Survivors' Quality of Life
- Family Support in Illness
- BRCA gene mutations in cancer
- Spine and Intervertebral Disc Pathology
- Child and Adolescent Health
- Primary Care and Health Outcomes
- Hip and Femur Fractures
- Clinical practice guidelines implementation
- Mental Health Research Topics
- Prostate Cancer Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- Colorectal Cancer Screening and Detection
- Evaluation and Performance Assessment
- Empathy and Medical Education
- Health, psychology, and well-being
- Statistical Methods in Clinical Trials
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Bangor University
2015-2024
University of the West of England
2019-2024
Royal Air Force College Cranwell
2021
Leeds Teaching Hospitals NHS Trust
2011-2019
Universidade Federal de Minas Gerais
2019
Primary Health Care
2018
St James's University Hospital
2015
Merck Serono (Italy)
2014
Cardiff University
1989-2013
University of Wales
1996-2008
Background This is the first report on epidemiology of depressive disorders from European Outcome Depression International Network (ODIN) study. Aims To assess prevalence in randomly selected samples general population five countries. Method The study was designed as a cross-sectional two-phase community using Beck Inventory during Phase 1, and Schedule for Clinical Assessment Neuropsychiatry 2. Results An analysis combined sample ( n =8.764) gave an overall 8.56% (95% Cl 7.05–10.37)....
<h3>Abstract</h3> <b>Objectives:</b> To determine the acceptability of two psychological interventions for depressed adults in community and their effect on caseness, symptoms, subjective function. <b>Design:</b> A pragmatic multicentre randomised controlled trial, stratified by centre. <b>Setting:</b> Nine urban rural communities Finland, Republic Ireland, Norway, Spain, United Kingdom. <b>Participants:</b> 452 participants aged 18 to 65, identified through a survey with depressive or...
Serum homocysteine is increased, and correlates inversely with cognitive scores, in Alzheimer’s disease (AD), vascular dementia ‘age-associated memory impairment’. Elevated levels might signal accelerated decline, although this remains to be established. We therefore repeated Mini-Mental State Examinations, together additional ADAS-Cog assessments, 32 healthy elderly individuals determine whether prior predicted changes over a 5-year period. Homocysteine follow-up scores rate of decline...
transit time.In patients with formed stools (scores 1-4) and normal or slow frequent defecation urgency are actually pseudodiarrhoea, presumably due to an irritable hyperreactive rectum, constipating agents should be avoided.As fast may respond differently high fibre diets bulking agents, respectively, perhaps they asked record their stool form so that the doctor can assess rate plan treatment.1 Rao SSC, Holdsworth CD, Read NW.Symptoms patterns in ulcerative colitis.
Background. Osteoarthritis (OA) of the knee is common and disabling. Exercise effective in reducing pain disability, but long-term adherence to exercise regimens disappointing, motivation those with OA poorly understood. Objectives. To examine views primary care patients towards exercise, explore factors that determine acceptability identify barriers limit its use. Method. Semi-structured interviews were conducted 22 knee, six whom also participated a focus group for triangulation....
Objective To explore ongoing symptoms, unmet needs, psychological wellbeing, self‐efficacy and overall health status in survivors of prostate cancer. Patients Methods An invitation to participate a postal questionnaire survey was sent 546 men, diagnosed with cancer 9–24 months previously at two UK centres. The study group comprised men who had been subject range treatments: surgery, radiotherapy, hormone therapy active surveillance. included measures prostate‐related quality life (Expanded...
The Outcomes of Depression International Network (ODIN) trial evaluated the effect two psychological interventions for treatment depression in primary care. Only about half patients arm complied with offer treatment, prompting question:'what was those who actually received it?'To illustrate estimation receipt a randomised controlled subject to non-compliance and loss follow-up.We estimated complier average causal (CACE) treatment.In ODIN intervention (an 4 points on Beck Inventory) is twice...
Abstract Objective Significant numbers of cancer patients suffer distress, reduced quality life and various other psychological problems. Evidence regarding predictors these outcomes is inconsistent. This study explored a range using an established framework to identify the most important adjustment, when are best assessed for optimal outcome prediction. Methods One hundred sixty newly diagnosed breast, colorectal, lung prostate completed questionnaires after diagnosis at 3‐ 6‐month...
Background and objectives: Referring clinicians’ experiences of exercise referral schemes (ERS) can provide valuable insights into their uptake. However, most qualitative studies focus on patient views only. This paper explores health professionals’ perceptions role in promoting physical activity a National Exercise Referral Scheme (NERS) Wales. Design: Qualitative semi-structured group interviews. Setting: General practice premises. Methods: Nine interviews involving 46 professionals were...
Background Folate deficiency is associated with depression. Despite the biological plausibility of a causal link, evidence that adding folate enhances antidepressant treatment weak. Objectives (1) Estimate clinical effectiveness and cost-effectiveness folic acid as adjunct to medication (ADM). (2) Explore whether baseline homocysteine predict response treatment. (3) Investigate depends on genetic polymorphisms related metabolism. Design FolATED (Folate Augmentation Treatment – Evaluation for...