A5065523303- Immunodeficiency and Autoimmune Disorders
- Antifungal resistance and susceptibility
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pediatric health and respiratory diseases
- Cytomegalovirus and herpesvirus research
- T-cell and B-cell Immunology
- Genetics, Bioinformatics, and Biomedical Research
- Transplantation: Methods and Outcomes
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Advanced Proteomics Techniques and Applications
- Cystic Fibrosis Research Advances
- Eosinophilic Esophagitis
- Mycobacterium research and diagnosis
- Antibiotics Pharmacokinetics and Efficacy
- Asthma and respiratory diseases
- Inflammasome and immune disorders
- Palliative Care and End-of-Life Issues
- Pneumocystis jirovecii pneumonia detection and treatment
- Immune responses and vaccinations
- Grief, Bereavement, and Mental Health
- Blood groups and transfusion
- Disaster Response and Management
- Immune Cell Function and Interaction
Oxford University Hospitals NHS Trust
2023
Harefield Hospital
2014-2015
Royal Brompton & Harefield NHS Foundation Trust
2011-2014
Churchill Hospital
2008-2012
Obstructive sleep apnoea syndrome (OSAS) has been associated with cardiovascular disease in epidemiological and observational studies. Continuous positive airway pressure (CPAP) is the treatment of choice for OSAS, but impact this intervention on systemic inflammation involved atherosclerotic process remains unclear.100 men moderate-severe OSAS were randomised to therapeutic (n = 51) or subtherapeutic 49) CPAP 4 weeks investigate effects active inflammatory markers such as highly sensitive C...
Summary Common variable immunodeficiency disorders (CVID) are a group of heterogeneous conditions that have in common primary failure B cell function, although numerous T abnormalities been described, including reduced proliferative response and regulatory cells. This study compared the phenotype CVID patients subdivided into clinical phenotypes as well with partial antibody deficiencies [immunoglobulin (Ig)G subclass deficiency selective IgA deficiency], X-linked agammaglobulinaemia (XLA)...
Summary Common variable immunodeficiency disorders (CVIDs) are a heterogeneous group of diseases characterized by hypogammaglobulinaemia and consequent susceptibility to infection. CVID patients commonly develop variety additional manifestations for which the causative factors not fully understood. Two such granulomatous disease enteropathy. Because ability predict complications would aid clinical management, we continue search possible modifier genes. NOD2 acts microbial sensor is involved...
<h3>Background</h3> Most people would prefer to die at home (Office for National Statistics. survey of bereaved (VOICES). 2016), yet less than 50% do (Nuffield Trust. End-of-life-care. 2023). Oxfordshire is an outlier persons with three or more non-elective admissions during the last 90 days life 8.82% (English average 7.4%), Health Improvement and Disparities. Atlas variation (Palliative end care), 2018). <h3>Aims</h3> To facilitate personalised care including fulfilling choices, whilst...