- Mathematical Biology Tumor Growth
- Gene Regulatory Network Analysis
- Evolution and Genetic Dynamics
- Cellular Mechanics and Interactions
- Single-cell and spatial transcriptomics
- Mathematical and Theoretical Epidemiology and Ecology Models
- MicroRNA in disease regulation
- Coastal wetland ecosystem dynamics
- 3D Printing in Biomedical Research
- Cancer-related molecular mechanisms research
- Mesenchymal stem cell research
- Microtubule and mitosis dynamics
- Organ Transplantation Techniques and Outcomes
- Cancer Cells and Metastasis
- Advanced Materials Characterization Techniques
- Microfluidic and Bio-sensing Technologies
- Diffusion and Search Dynamics
- Fern and Epiphyte Biology
- Evolutionary Game Theory and Cooperation
- Angiogenesis and VEGF in Cancer
- Advanced Proteomics Techniques and Applications
- Geochemistry and Elemental Analysis
- Environmental Philosophy and Ethics
- Landslides and related hazards
- Tendon Structure and Treatment
Okayama University
2025
Ruijin Hospital
2012-2024
Shanghai Jiao Tong University
2011-2024
Shanghai Institute of Hematology
2012-2024
Xi'an Jiaotong University
2024
First Hospital of China Medical University
2024
China Medical University
2024
China Geological Survey
2024
Nanjing University of Chinese Medicine
2024
Qingdao Institute of Marine Geology
2019-2024
The Fisher-Kolmogorov-Petrovsky-Piskunov model, also known as the Fisher-KPP supports travelling wave solutions that are successfully used to model numerous invasive phenomena with applications in biology, ecology and combustion theory. However, there certain cannot replicate, such extinction of populations. Fisher-Stefan is an adaptation include a moving boundary whose evolution governed by Stefan condition. solutions; however, key additional feature it able simulate population extinction,...
Two-dimensional collective cell migration assays are used to study cancer and tissue repair. These involve combined proliferation processes, both of which modulated by cell-to-cell crowding. Previous discrete models a nearest-neighbour mechanism where crowding effects incorporated aborting potential events if the randomly chosen target site is occupied. There two limitations this traditional approach: (i) it seems unreasonable abort event based on occupancy single, site; and, (ii) continuum...
Rationale: Adipose tissue buffers dietary lipids to maintain postprandial lipid homeostasis. macrophages (ATMs) mediate the phagocytosis of from exogenous diet, generating high-density lipoprotein (HDL) particles that facilitate circulation and excretion. However, underlying mechanisms remain poorly understood. This study investigates effects esculetin, a coumarin compound, on cholesterol excretion following high-fat meal. Methods: Mice were fed lipid-rich meal for three days assess...
Abstract Arbuscular mycorrhizal fungi (AMF) is presumably to be associated with carbon sequestration and nutrient acquisition through mineral weathering in wetland ecosystems. However, information on AMF‐carbon‐weathering interactions limited. Grain size, concentrations of nutrients, the major components 304 surface sediment samples glomalin‐related soil protein (GRSP) 133 were analyzed various environments, including upper delta plain wetlands (UDPW) its adjacent shallow sea (SSW), evaluate...
Scratch assays are routinely used to study collective cell behaviour in vitro . Typical experimental protocols do not vary the initial density of cells, and typical mathematical modelling approaches describe motility proliferation based on assumptions linear diffusion logistic growth. Jin et al. (Jin al 2016 J. Theor. Biol. 390 , 136–145 ( doi:10.1016/j.jtbi.2015.10.040 )) find that cells scratch is density-dependent, show standard cannot simultaneously data initiated across a range...
In vitro cell culture is routinely used to grow and supply a sufficiently large number of cells for various types biology experiments. Previous experimental studies report that characteristics evolve as the passage increases, lines can behave differently at high numbers. To provide insight into putative mechanisms might give rise these differences, we perform in silico experiments using random walk model mimic process. Our results show it possible average proliferation rate either increase...
Abstract The world's coral reefs are under threat as climate change causes increases in frequency and severity of acute thermal stress. This is compounded by chronic pressures including rises sea surface temperature, overfishing decline water quality. Monitoring to understand the recovery dynamics corals paramount enable effective management reefs. While detailed mechanistic models provide insight into reef patterns, colony scale monitoring not viable for over a large geographical extent,...
Abstract In vitro cell culture is routinely used to grow and supply a sufficiently large number of cells for various types biology experiments. Previous experimental studies report that characteristics evolve as the passage increases, lines can behave differently at high numbers. To provide insight into putative mechanisms might give rise these differences, we perform in silico experiments using random walk model mimic process. Our results show it possible average proliferation rate either...
Abstract Cell proliferation is the most important cellular-level mechanism responsible for regulating cell population dynamics in living tissues. Modern experimental procedures show that rates of individual cells can vary significantly within same line. However, mathematical biology literature, typically modelled using a classical logistic equation which neglects variations rate. In this work, we consider discrete model migration and proliferation, modulated by volume exclusion (crowding)...