A5091439600- Ectopic Pregnancy Diagnosis and Management
- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Screening and Diagnostics
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Thyroid Cancer Diagnosis and Treatment
- Radiology practices and education
- Fetal and Pediatric Neurological Disorders
- Ovarian cancer diagnosis and treatment
- Head and Neck Anomalies
- Congenital Anomalies and Fetal Surgery
- Thyroid and Parathyroid Surgery
- Gestational Trophoblastic Disease Studies
- Gynecological conditions and treatments
- Maternal and fetal healthcare
- Ultrasound in Clinical Applications
- Uterine Myomas and Treatments
- Appendicitis Diagnosis and Management
- Congenital Diaphragmatic Hernia Studies
- Endometriosis Research and Treatment
- Gestational Diabetes Research and Management
- Radiation Dose and Imaging
- Neonatal and fetal brain pathology
- BRCA gene mutations in cancer
- Neonatal Respiratory Health Research
Brigham and Women's Hospital
2014-2024
Harvard University
2014-2024
Columbia College - South Carolina
2024
University of Southern California
2023-2024
Texas Children's Hospital
2018-2024
Baylor College of Medicine
2018-2024
Northeast Ohio Medical University
2019-2024
University of Alabama at Birmingham
2019-2024
Thomas Jefferson University
2018-2024
Einstein Healthcare Network
2024
The data for medical decision analyses are often unreliable. Traditional sensitivity analysis--varying one or more probability utility estimates from baseline values to see if the optimal strategy changes--is cumbersome than two allowed vary concurrently. This paper describes a practical method probabilistic analysis, in which uncertainties all considered simultaneously. uncertainty each and is assumed possess distribution. For ease of application we have used parametric model that permits...
BACKGROUND. The diagnostic evaluation of patients with thyroid nodules is imprecise. Despite the benefits fine-needle aspiration (FNA), most who are referred for surgery because abnormal cytology prove to have benign disease. Recent technologic and procedural advances suggest that this shortcoming can be mitigated, although few data confirm benefit in unselected patients. METHODS. A total 2587 sequential were evaluated by ultrasound offered ultrasound-guided FNA (UG-FNA) all measured ≥1 cm...
Objective: The objective of this study was to determine the prevalence, distribution, and sonographic features thyroid cancer in patients with solitary multiple nodules.
There has been mounting pressure on the medical profession in recent years to stem rise national health care expenditures. One result of that popularization term "cost effective" medicine. Examples its use abound literature, drug and equipment advertisements, hallways lecture halls institutions. Unfortunately, many who assert a specified practice is cost effective fail couple statement with appropriate documentation associated costs benefits.1 Even when these have computed, conclusions drawn...
Thyroid nodule size is routinely measured, although its impact on thyroid cancer risk unclear.Our objective was to evaluate the association of upon risk.We conducted a retrospective cohort analysis at an academic hospital with 4955 consecutive patients evaluated between 1995 and 2009.Ultrasound ultrasound-guided fine-needle aspiration nodules >1 cm done. Indeterminate malignant were referred for surgery, histopathology reviewed.The presence histological subtype evaluated.Of 7348 nodules, 927...
Thyroid cancer is the most common endocrine malignancy, but due to its rare occurrence in pediatric population, risk of childhood thyroid nodules incompletely defined, and optimal management children with suspected debated.The aim was study presenting features sporadic using a standardized clinical assessment plan.Boston Children's Hospital Brigham Women's collaborated create multidisciplinary nodule clinic implement plan. Upon referral for nodule, serum TSH measured hypothyrotropinemic...
Abstract Thyroid nodules are common. Evaluation of patients with thyroid typically includes fine needle aspiration biopsy (FNA), an approach that has proven to be accurate for the detection cancer. Although majority biopsies adequate a cytological diagnosis, up 20% will insufficient or nondiagnostic. Current opinion suggests such aspirates should repeated, although no systematic study investigated usefulness this approach, especially when ultrasound guidance is used direct initial FNA. We...
Objective. To determine whether color Doppler interrogation of a thyroid nodule can aid in the prediction malignancy. Methods. We obtained images nodules undergoing sonographically guided fine-needle aspiration. The appearance each was graded from 0 for no visible flow through 4 extensive internal flow. size, sonographic appearance, results aspiration, and surgical pathologic findings, if available, were recorded nodule. Results. There 254 sampled, which 32 malignant (all confirmed at...
Background: Thyroid nodules are common and most often benign. The natural history of benign thyroid nodules, however, is unclear. Objective: To determine the cytologically using ultrasonography. Design: Retrospective case series. Setting: Single tertiary care clinic. Participants: All patients referred to Brigham Women's Hospital Nodule Clinic, Boston, Massachusetts, who had cytologic results on ultrasonography-guided fine-needle aspiration a nodule between 1995 2000 returned for requested...
To determine the gray-scale and Doppler sonographic features that best enable discrimination between malignant benign ovarian masses develop a scoring system for accurate diagnosis with these features.Gray-scale of 211 adnexal were correlated final diagnosis; most discriminating malignancy selected stepwise logistic regression.Twenty-eight 183 benign. All markedly hyperechoic solid component or no For nonhyperechoic component, additional allowed statistically significant benignity from were,...
The Society of Radiologists in Ultrasound convened a panel specialists from variety medical disciplines to come consensus on the management thyroid nodules identified with ultrasonography (US), particular focus which should be subjected US-guided fine needle aspiration and need not fine-needle aspiration. met Washington, DC, October 26-27, 2004, created this statement. recommendations statement, are based analysis current literature common practice strategies, thought represent reasonable...
Interpretation of radiographs: effect clinical historyP Doubilet and PG HermanAudio Available | Share
Background The American College of Radiology (ACR) Thyroid Imaging Reporting and Data System (TI-RADS) is a recognized tool for management thyroid nodules in adults but has not been validated pediatric patients. Purpose To assess the performance ACR TI-RADS criteria guiding decisions on whether to biopsy patients single referral center. Materials Methods In this retrospective study, database younger than 19 years who underwent fine-needle aspiration (FNA) between January 2004 July 2017 was...
To review experience with early sonographic diagnosis and fertility-preserving treatment of cervical ectopic pregnancy.The authors evaluated 12 consecutive cases pregnancy diagnosed ultrasound (US) treated methods that successfully preserved the uterus. Gestational age, findings, means conception, method were recorded.Gestational age at ranged from 5.0 to 7.9 weeks. Cardiac activity was documented in nine cases. Patients as follows: transvaginal US-guided injection potassium chloride into...
We assessed the outcome of pregnancies in women with uterine leiomyomas (fibroids) documented by sonography first trimester pregnancy.We collected cases who had undergone first-trimester and fibroids singleton fetal heartbeats. compared pregnancy loss rates modes delivery these to a maternal-age-matched gestational-age-matched control group normal uteruses Sonograms patients were reviewed determine number fibroids, their sizes, locations. Within rate was also based on fibroid size...
Because intraventricular hemorrhage (IVH) often precedes the development of sonographically defined white matter damage (WMD) in very preterm infants, we sought to identify IVH characteristics that predict WMD.We evaluated variations on null hypothesis infants with are no more likely than without have WMD. These dealt (presence or absence ventriculomegaly) WMD (size, localization, and laterality).A total 1605 weighing 500 1500 g at birth between January 1991 December 1993 underwent...
Background: Thyroid nodules are common; the vast majority benign. Preoperative determination of malignancy remains imprecise, despite fine-needle aspiration (FNA). Numerous risk factors have been proposed for predicting malignancy, though few found useful. Oxygen delivery is a crucial component tumor cell growth. It has hypothesized that malignant tumors may configure their shape to maximize access local nutrient delivery. Mathematically, surface area volume maximized by spherical shape. We...
Abstract Despite the considerable literature on overuse of new medical technologies, little attention has been paid to biologic and monetary costs that may be incurred by underuse. Percutaneous transluminal angioplasty as a treatment for peripheral vascular disease is an example important technology under-used. Although alone less costly but also efficacious than surgery, strategy combines two procedures (angioplasty first, then surgery if unsuccessful or occlusion recurs) uniformly superior...