Various skin parameters including visco-elasticity and hydration level affect the formation of wrinkles.The aim this study was to investigate comprehensive objective relationship between age, visco-elasticity, level, occurrence wrinkles using bioengineering equipments for first time.A total number 97 healthy women were included in study. Age, Fitzpatrick type, mechanical obtained with Cutometer(R0~R9), measured Corneometer, as well wrinkle (SEsm, SEr, SEsc, SEw) assessed Visioscan, analyzed...

The assessment of the severity psoriasis is often subjective because lack quantitative laboratory diagnostic tools. Histopathological examination most commonly performed procedure for diagnosis; however, it usually descriptive. Thus, there currently no method determining severity. clinical types are correlated with disease, and a lesional index, such as index (PSI), could be used tool assessing gross To correlate histopathological findings PSI. Psoriatic lesions in 98 patients were...

Despite several recent reports on the efficacy of long-pulse pulsed dye laser (LP-PDL) in treating infantile hemangiomas, controversy remains.To determine beneficial effects early therapeutic intervention with LP-PDL superficial and mixed hemangiomas.Clinical data from 40 children 47 hemangiomas preproliferative or proliferative phase treated a Korean tertiary hospital over 5 years were analyzed retrospectively. Treatments repeated at 1- to 4-week intervals until growth stopped.Of 32...

Rosacea and seborrhoeic dermatitis are common diseases that cause facial erythema. They have features frequently misdiagnosed.To extract characteristic of erythrotelangiectatic rosacea (ETR), papulopustular (PPR) (SEB) through computer-aided image analysis (CAIA) compare them with subjectively recognized to use these findings construct a decision tree for differential diagnosis.Thirty-four clinical photos patients erythema were assessed: 12 classified as showing ETR, PPR 10 SEB. Five...

Background: Cryotherapy has been accepted as the mainstay in treating periunugal and palmoplantar warts.The major drawback of cryotherapy is requirement several unbearably painful treatment sessions.Objective: This study aims to assess efficacy immunotherapy viral wart treatment, an adjunctive method cryotherapy.Methods: Retrospective chart review was performed on 124 patients visiting hospital from January December 2009 for periungual plantar warts.We analyzed number sessions necessary...

Most conventional subjective assessments for psoriasis have inevitable inter- and intra-observer variations. We investigated the objective bioengineering parameters of color mechanical properties which are possible substitutes erythema, scale, thickness scores psoriatic plaque. Age, gender, Psoriasis Severity Index (PSI) were noted. In addition, color, properties, scale obtained. The most prominently correlated hue (tan(-1) b*/a*), desquamation index (DI), elasticity (R7) PSI thickness,...

Dear Editor: A 15-day-old boy visited our clinic presenting a palm sized erythematous patch located on his left cheek from birth, which was aggravated soon after 1st vaccination against the hepatitis B virus. A skin biopsy revealed an oval shaped vascular lobules scattered in dermis. It typical 'Cannonball' appearance (Fig. 1A). In high power field, were groups of ducts composed proliferated endothelial cells. Tufted angioma (TA) most consistent diagnosis. The patient began receiving...

Background We usually divided cosmetic facial zone into the T and U by level of sebum secretion. Our recent studies suggested that perioral area showed different characteristics in aspect acne development. Objective To investigate unique O (perioral area) among three areas. Methods A total 102 patients clinically diagnosed as vulgaris were included. The lesions counted from clinical digital photographs was measured using Sebumeter ® . Area‐weighted ( AW ) density areas face calculated....

occurred in our case.Atypical presentations of tinea faciei can lead to misdiagnosis.The present case underlines that physicians should keep mind clinical features superficial fungal infection be substantially modified by incorrect treatment, mimic even herpes simplex virus infection.Fungal on the list differential diagnoses facial eruptions, especially cases not responding preceding management.

Because nail psoriasis is difficult to treat, therapy with many biological drugs has been attempted. Ustekinumab approved for chronic plaque and psoriatic arthritis (PsA), some trials reporting improvement using this agent. A 51-year-old man severe had involvement of all fingernails toenails, accompanying fold psoriasis. He also PsA the small joints fingers. Despite multiple conventional therapies, lesions did not improve, his severity index score was 97. After a fourth ustekinumab...

Background: Hair graying is considered as a part of normal ageing process.Nonetheless, this process raises significant cosmetic concern, especially among ethnic Korean elderly whose baseline hair color black.For reason, dye their with frequency despite the risk dermatologic problems such allergic contact dermatitis.Objective: In study, authors investigate prevalence and pattern dyeing its relation scalp diseases in Korea.Methods: Six hundred twenty subjects (330 men 290 women) were given...

Propranolol has recently become a successful first-line therapy in the treatment of infantile hemangiomas (IHs).To evaluate and analyze authors' experience propranolol for IHs.A retrospective, observational study was conducted. Medical records were reviewed. To outcome treatment, serial digital photographs using visual analog scale compared.Eighty-three patients with mean age 5.35 ± 5.15 months had 107 IHs treated by oral at dose 2 mg/kg/day. The percent improvement size extent 14.3% 1 week,...

Background Facial erythema is a common but morbid condition caused by several inflammatory disorders. Since most of the current severity indexes lack objectivity and global assessment, computer‐aided image analysis ( CAIA ) has been suggested. Objective The purpose this study to compare validity efficacy novel index – dose ED with two other indexes. Methods For mild, moderated severe erytherotelangiectatic rosacea patients, their photographs right cheek were assessed red‐blue difference in...

To establish an efficient multiplex real-time PCR assay for 15 human papillomavirus (HPV) genotypes, we designed multiplexing parameters and compared our system with the hybrid capture (HC) II test using cervical cytology samples.For preventing cross-reactive amplifications, variable HPV genes (E1, E2, E6, E7 L1) were targeted. The melting temperatures of all primers probes, size product optimized PCR. Our was HC assays in detection genotyping infection 173 smears. Discordant cases between...

Pigmentation is induced by production of melanin in specialized organelles termed melanosomes and transfer these from melanocytes to surrounding keratinocytes. The chemical basis melanogenesis relatively well known but the mechanism melanosome not studied. Various pigmentary disorders cosmetic applications require use depigmenting agents. Currently available topical agents used for reduction pigmentation mainly include tyrosinase inhibitors and/or melanocyte-cytotoxic Recently, several have...

Recently, the demand for fast storages is rapidly increasing in HPC environments such as cloud platforms, social network services and desktop users. But HDD-based cannot satisfy these demands, a variety of high performance providing lower I/O latency higher bandwidth have been eagerly developed. Although merely adopting devices storage system can take some advantages, it fully utilize their performance. So, proper optimizations are needed. In this work, we focus on granularity request from...

Abstract Epidemiological study of Langerhans cell histiocytosis ( LCH ) has been limited due to its rarity and multisystemic involvement. The aim this was investigate the epidemiological features via clinical data warehouse CDW ). Clinical 30 patients from all departments a tertiary referral hospital between 2003 2012 were analyzed retrospectively by searching . male‐to‐female ratio 2.8:1. age onset ranged 7 days 57 years with median 13 years. Of patients, 36.7% presented initial symptoms...

Adequate pain management is a critical component of facilitating same-day discharge for total knee arthroplasty (TKA). Adductor canal blocks (ACB) have been shown to be an effective technique managing after TKA. The objective this study was investigate the impact adding magnesium local anesthetic in ACB on postoperative pain, opioid consumption, nausea, and overall patient satisfaction.A sample 119 adults undergoing elective unilateral TKA were included. Patients randomly assigned receive...

Storage area network (SAN) is one of the most popular solutions for constructing server environments these days. In kinds environments, HDD-based storage usually becomes bottleneck overall system, but it not enough to merely replace devices with faster ones in order exploit their high performance. other words, proper optimizations are needed fully utilize performance gains. this work, we first adopted a DRAM-based SSD as fast backend-storage existing SAN environment, and found significant...

Background:The differential diagnosis of common pigmented skin lesions is important in cosmetic dermatology.The computer aided image analysis would be a potent ancillary diagnostic tool when patients are hesitant to undergo biopsy.Objective: We investigated the numerical parameters discriminating each lesion from another with statistical significance.Methods: For five magnified digital images containing clinically diagnosed nevus, lentigo and seborrheic keratosis, total 23 describing...

SUMMARY Objectives The study was designed to evaluate the effect of warfarin on perioperative transfusion, bleeding and coagulation status in patients undergoing cardiac surgery with cardiopulmonary bypass ( CPB ). Background There were controversy about transfusion bleeding. Methods/Materials Medical records from 107 consecutive atrial fibrillation AF ) therapy 2008 2013 at a single university teaching hospital retrospectively reviewed compare those not terms requirement, postoperative 24‐h...

Abstract The erythema, scale and thickness of psoriasis lesions could be converted to bioengineering parameters. An objective severity assessment is advantageous in terms accuracy reproducibility over conventional assessment. We aimed formulate an index with a single device that can possibly substitute the subjective Psoriasis Severity Index. A linear regression analysis was performed derive formula Index as dependent variable various parameters determined from 157 independent variables....