A5100701694- Acute Ischemic Stroke Management
- Sleep and Wakefulness Research
- Sleep and related disorders
- Advanced biosensing and bioanalysis techniques
- Receptor Mechanisms and Signaling
- Cerebrovascular and Carotid Artery Diseases
- Inflammatory Biomarkers in Disease Prognosis
- Diabetes Treatment and Management
- Circadian rhythm and melatonin
- Neurological Disorders and Treatments
- Neuropeptides and Animal Physiology
- Intracerebral and Subarachnoid Hemorrhage Research
- Molecular Biology Techniques and Applications
- Bacteriophages and microbial interactions
Huashan Hospital
2022-2025
Fudan University
2020-2023
Choosing a partner that fits G protein–coupled receptors (GPCRs) are responsible for transducing diverse signals from outside to inside cells. This process requires specificity both in ligand binding GPCRs and coupling between their intracellular partners, proteins. Qiao et al. determined the structure of human glucagon receptor (GCGR), type B GPCR, bound one two heterotrimeric proteins, s or i1 . GCGR mainly through , structures provide basis this specificity. Conformational changes GCGR,...
Background: A novel inflammatory score has been validated for hematoma expansion and poor outcomes in patients with intracerebral hemorrhage. This study aimed to explore its capacity of predicting hemorrhagic transformation risk prognosis suffering ischemic stroke. Method: We retrospectively analyzed stroke three clinical centers from 1 January 2012 31 December 2023 based on hospital electronic case records. matched case-control was conducted reducing the impact various confounding factors....
Abstract Objectives Insomnia was associated with cerebral structural changes and Alzheimer’s disease. However, associations among perfusion, insomnia small vessel disease (CSVD), cognitive performance were little investigated. Methods This cross-sectional study included 89 patients CSVDs white matter hyperintensities (WMHs). They dichotomized into the normal sleep poor group, according to Pittsburgh quality index (PSQI). Baseline characteristics, performance, blood flow (CBF) measured...
Abstract Background and Purpose: Cerebral small vessel damages large artery atherosclerotic (LAA) stroke share many risk factors, such as inflammation, but little attention has been paid to the relationship between cerebral with inflammation in predicting outcomes. Methods: We consecutively enrolled participants LAA collected their baseline follow-up data, especially imaging markers of disease C reactive protein (CRP), neutrophil-to-lymphocyte ratio (NLR) levels. The primary outcomes were at...