In order to elucidate the role of insulin and glucagon during strenuous exercise (100 m/min, slope 10-12 degrees), we have determined rates production (Ra), utilization (Rd), metabolic clearance (M) glucose in normal dogs before pancreatectomy 2 wk after total (a) when they were being maintained on constant intraportal basal infusion, (245 muU/kg-min) (b) supply had been withheld exercise. Such an intense induced a prompt decrease mean immunoreactive serum (IRI) from 20 +/- 3 11 muU/ml....

Abstract Basil (sweet basil, Ocimum basilicum L.) is an aromatic plant known for its culinary and traditional medicinal uses. The content of estragole (methyl chavicol), a compound associated with potential risk to human health, was determined in the essential oils 12 samples basil herb by gas chromatography flame ionisation mass spectrometry detection (GC-FID/MS) using external standard method. contained at various levels, from 1.85 561.01 mg mL −1 . Regarding chemical profile, among eleven...

Abstract The essential oils of seven Teucrium species (T. arduini L., T. botrys chamaedrys flavum montanum polium scordium L.) growing wild in Serbia and Montenegro were studied by GC GC/MS. More than 60 compounds identified. main constituents β-caryophyllene (24.5%; 26.9%) germacrene D (21.9%; 22.8%), respectively. oil contained (20.4%), α-humulene (13.9%) (E)-β-farnesene (17.7%), while α-pinene (17.5%), β-pinene (11.5) β-bisabolene (35.0%). was rich (17.7%) (10.0 %), (12.4%), (15.0%)...

In this study, we investigated the antimicrobial activity of young shoots smoke tree, Cotinus coggygria Scop., Anacardiaceae. The acetone extract and derived ethyl acetate fraction effectively inhibited growth Gram‐positive Gram‐negative bacteria (MIC 25–200 µg/ml), while chloroform showed pronounced against yeast Candida albicans 3.12 µg/ml). exhibited a significant ferric‐reducing ability (10.7 mmol Fe 2+ /g extract), very high DPPH radical scavenging (SC 50 = 1.7 µg/ml) inhibition lipid...

Abstract The composition of the essential oils Achillea lingulata and A. umbellata were analysed by GC GC–MS. Among determined constituents, borneol, bornyl acetate, camphor, α ‐ β ‐thujone, 1,8‐cineol found as main components. Copyright © 2007 John Wiley & Sons, Ltd.

To evaluate different biochemical markers and their ratios in the assessment of primary biliary cirrhosis (PBC) stages.This study included 112 patients with PBC who underwent a complete clinical investigation. We analyzed correlation (Spearman's test) between ten stages PBC. The discriminative values were compared using areas under receiver operating characteristic (ROC) curves.The mean age was 53.88 +/- 10.59 years, including 104 females 8 males. found statistically significant stage...

The methanol extract of ripe Rumex crispus L. fruits was evaluated for its antioxidant potential by assays ferric-reducing power (FRAP), DPPH-free radical scavenging activity (DPPH) and the influence on lipid peroxidation in liposomes (LP). Considerable observed all test systems (FRAP: 9.9 mmol Fe(2+) /g; DPPH IC(50) : 3.7 μg/mL; LP 4.9 μg/mL), comparable to that BHT 8.0 19.4 3.5 but lower than ascorbic acid, rutin quercetin, used as positive control substances. vivo effects were several...

Arbutus unedo leaf is used traditionally for gastrointestinal complaints. Ethanol extracts from collected in both Montenegro (AuM) and Greece (AuG) were found to decrease the ileal basal tonus, with AuG producing a significantly higher ( p < 0.05) reduction contractile response acetylcholine. AuM relaxed 80 m K + induced contractions shifted Ca ++ concentration–response curves right, similar that caused by verapamil, suggesting spasmolytic effect was through calcium channel inhibition....

The present paper describes environmental and seasonal-related chemical composition variations, vasorelaxant angiotensin I-converting enzyme (ACE) activities of essential oil from aerial parts Seseli pallasii Besser. was analyzed by GC GC/MS. Monoterpenes were found to be the most abundant class with α-pinene (42.7 - 48.2%) as prevalent component. pallasi relaxed isolated endothelium-intact mesenteric arteries rings precontracted phenylephrine IC50 = 3.10 nl/ml (IC50 2.70 μg/ml). Also, S....

It has been shown previously that glucagon can increase the turnover of glucose in normal dogs and enhance secretion insulin. The aim this study was to determine metabolic effects independent insulin it releases directly through an action on β cells, indirectly hyperglycemia. Eight conscious which could not mobilize extra were obtained by replacing endogenous each with equivalent intraportal infusion hormone immediately following removal a remnant pancreatic autograft. Such infusions (200...

In recent years mental health of patients including those with chronic liver disease (CLD), has become interesting because its disturbance leads to reduced quality life, that is associated worsening clinical outcome, compliance and increased mortality. The aim the study was determinate frequency severity depression anxiety in CLD assess contribution selected socio-demographic, laboratory risk factors for anxiety.In this cross-sectional study, we used Hamilton rating scale (HDRS) (HARS)...

Introducing patient safety and quality improvement science to medical students is integral improving healthcare. However, developing implementing a curriculum can be challenging in school that already densely packed. Our aim was develop evaluate the impact of workshop introducing large class first-year students. As part an evolving longitudinal curriculum, introductory on integrated into anatomy course. A high event (a simulated "retained sponge" discovery during dissection lab) used...

In pups less than 4 days old, the mean basal plasma immunoreactive glucagon (IRG) level was about 3 times higher in adult dogs. This high decreased with age, and older 12 IRG did not differ from that adults. Insulin-induced hypoglycemia raise concentration young pups. Fasting young, but decrease is consistent gluconeogenesis contrast to metabolic adjustments observed organism. 7 both pancreas gastric mucosa contained considerably more normal value reported for Gastroduodenal immunologically...