Black locust flower extract contains various polyphenols and their glucosides contribute to the potential health benefits. After intake of these bioactive compounds passage through gastrointestinal tract, degradation can occur lead a loss biological activity. To overcome this problem, should be protected from environmental conditions. This study aimed encapsulate black in microparticles based on biodegradable polysaccharides, alginate, chitosan. In extract, total antioxidant content was...

The genetic, morphological and taxonomic diversity of the genus Sorbus is due to homoploid polyploid hybridisation, autopolyploidy apomixis, which also influence production secondary metabolites, especially flavonoids. aim this study was investigate relationships variations flavonoids in terms hybrid origin ploidy level between parental species their derivatives. sampling design included leaf material following accessions from ten natural localities: taxa (di-, tri- tetraploids S. aria;...

Abstract The composition of the essential oils Achillea lingulata and A. umbellata were analysed by GC GC–MS. Among determined constituents, borneol, bornyl acetate, camphor, α ‐ β ‐thujone, 1,8‐cineol found as main components. Copyright © 2007 John Wiley & Sons, Ltd.

The commercial samples of aerial parts Origanum vulgare L. and Ocimum basilicum (Lamiaceae) were tested for antimicrobial activity. activity the extracts with different polarity was against a panel microorganisms, including laboratory strain Helicobacter pylori NCTC 12868. showed moderate O. more active bacteria, especially Gram positive bacteria minimal inhibitory concentration (MIC) between 62.5 125 μg/mL, than which Candida albicans (MIC μg/mL). Cyclohexane extract did not show any H....

The present paper describes environmental and seasonal-related chemical composition variations, vasorelaxant angiotensin I-converting enzyme (ACE) activities of essential oil from aerial parts Seseli pallasii Besser. was analyzed by GC GC/MS. Monoterpenes were found to be the most abundant class with α-pinene (42.7 - 48.2%) as prevalent component. pallasi relaxed isolated endothelium-intact mesenteric arteries rings precontracted phenylephrine IC50 = 3.10 nl/ml (IC50 2.70 μg/ml). Also, S....

The antimicrobial and cytotoxic activities of the essential oil Satureja montana ssp. pisidica from two localities (mountains Korab Galičica) were studied. Forty-nine components identified in each sample. Oxygenated monoterpene hydrocarbons major compounds: carvacrol, thymol, carvacrol methyl ether β-linalool. Both tested oils showed very high similar activity. Minimal inhibitory concentrations ranged 12.5 μg/mL against S. epidermidis to 50 P. aeruginosa C. albicans. effect was MDA-MB-361,...

Antibacterial and cytotoxic activities of cyclohexane, dichloromethane, methanol, aqueous extracts Cantharellus cibarius were tested. Broth microdilution assay was performed against 10 bacterial strains (Staphylococcus aureus, S. epidermidis, Micrococcus luteus, Bacillus subtilis, Enterococcus feacalis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella abony), with emphasis on Helicobacter pylori. Methanol extract the most active H. pylori minimal inhibitory...

The aim of this paper was to estimate the biological activity plum seed extract and define chemical composition by using ESI-MS method. During investigation antioxidant activity, showed a better ability inhibit DPPH radicals compared with amygdalin standard. results antimicrobial study indicate that has greater effect on Gram-negative bacteria amygdalin. Gram-positive fungi remained resistant in both cases. Unlike amygdalin, against same microbiological strains. Amygdalin isolated from...

Three seaweeds (Halimeda tuna, Codium bursa and Cystoseira barbata) one seagrass (Cymodocea nodosa) were collected from the Coast of Montenegro, Gulf Boka Kotorska their chemical analysis was performed. In C. nodosa, three phenolic compounds identified (diosmetin 7-sulfate, caftaric coutaric acid). The content β-glucan, fatty acids, sterols micro- macro-elements investigated among all samples. highest β-glucan detected in nodosa (13.04±0.42 g/100 g). polyunsaturated acids (PUFAs) level...

The composition of the essential oil obtained by hydrodistillation from aerial parts Satureja kitaibelii Rtanj mountain (Serbia), collected during three years, was studied. Thirty-nine components were identified in each sample S. oil, representing about 87% oils. p-Cymene most dominant compound all oils (27.9%, 14.7% and 24.4%, respectively). simple formulation a lozenge with 0.2% prepared antimicrobial activity tested using broth microdilution assay. Both possessed strong MIC values 0.10-25...

Stimulus-sensitive hydrogels are used as carriers for modified release of pharmaceuticals. The synthesis thermosensitive poly(N-isopropylacrylamide), p(NIPAM), and poly(N-isopropylacrylamide-co-2-hydroxypropyl methacrylate), p(NIPAM-HPMet), is performed. synthesized characterized using FTIR scanning electron microscope methods swelling properties, applied ellagic acid (EA). This work presents the selective extraction EA, a natural antioxidant, from aerial parts Alchemilla vulgaris L. EA A....

Abstract The different parts of Sorbus torminalis (L.) Crantz are used in traditional medicine for various conditions such as cardiac diseases, cough, and diabetes, indicating its significant medicinal potential. Therefore, the current investigation aimed to reveal phenolic composition poorly studied S. methanol extract bark, well capacity inhibit enzymes relevant cardiovascular, neurodegenerative, metabolic diseases. A total 28 components, including 20 procyanidins aglycones (A‐ B‐type),...

Cyclohexane and methanol extracts of leaves inflorescences Ampelopsis brevipedunculata Parthenocissus tricuspidata are shown to exert significant cytotoxic action on both estrogen-dependent (MDA-MB-361) estrogen-nondependent (MDA-MB-453) breast cancer cell lines. Methanol P. exhibited higher cytotoxicity for the MDA-MB-453 line (inflorescence: IC50 =111.45 ? 2.56 ?g/ml; leaves: IC50= 56.76 7.11 ?g/ml) than MDA-MB-361. A. high against (IC50 =78.32 0.1 MDA-MB-361 =97.40 2.61 ?g/ml). The...

Background: Venous ulcers (ulcus cruris venosum) are a common chronic disease that requires continuing treatment and significantly influences patient's way of life. The therapeutic effects the ointment Herbadermal on epithelialization microbial flora venous in 25 patients (10 men 15 women) were tested over 7-week period. major components extracts garlic, St. John's wort, calendula. Material Methods: 18 years age, with ulceration lower leg no longer than 2 months or recurrent during last 6...

Cytotoxicity and antimicrobial activity of cyclohexane, dichlormethane methanol extracts Teucrium scordium subspec. scordioides was studied. Cyclohexane T. possessed high citotoxicity against MDA-MB-361 cells (IC50=130.33±0.1 μg/ml IC50=189.89±3.99 μg/ml, respectively). Dichlormethane extract more effective MDA-MB-453 cell line (IC50=130.33 ± 0.1 μg/ml). The no cytotoxicity breast cancer lines, MDA-MB-453. Herb have shown weak antibacterial on Pseudomonas aeruginosa, Klebsiella pneumoniae,...

Since the outbreak of COVID-19 pandemic, it has been obvious that virus infection poses a serious threat to human health on global scale. Certain plants, particularly those rich in polyphenols, have found be effective antiviral agents. The effectiveness Alchemilla viridiflora Rothm. (Rosaceae) methanol extract prevent contact between spike (S)-glycoprotein and angiotensin-converting enzyme 2 (ACE2) neuropilin-1 (NRP1) receptors was investigated. In vitro results revealed tested samples...

Investigation of the aerial parts Achillea alexandri-regis led to identification 19 chemical constituents: twelve 3-O-fatty acid esters triterpene alcohols arnidiol (1—4), maniladiol (5—8) and 16β-hydroxylupeol (9—12), α-amyrin, β-amyrin, β-sitosterol, 3,4-O-dicaffeoyl quinic acid, cinnamic pinoresinol-β-D-glucoside rutin. Among them, compounds 3, 4, 8, 11 12 are new natural products. The structures all have been elucidated on basis their spectral data.