A5103270570- Agricultural safety and regulations
- Effects and risks of endocrine disrupting chemicals
- Consumer Attitudes and Food Labeling
- Glaucoma and retinal disorders
- Carcinogens and Genotoxicity Assessment
- Pesticide Residue Analysis and Safety
- Aluminum toxicity and tolerance in plants and animals
- Food composition and properties
- Polysaccharides Composition and Applications
- Ocular Oncology and Treatments
- Cardiac Imaging and Diagnostics
- Magnesium in Health and Disease
- Cardiovascular Function and Risk Factors
- Celiac Disease Research and Management
- Exercise and Physiological Responses
- Retinal and Optic Conditions
- Cerebral Venous Sinus Thrombosis
- Nutritional Studies and Diet
- Trace Elements in Health
- Phytochemicals and Antioxidant Activities
- Dye analysis and toxicity
- Animal Nutrition and Physiology
- Medical and Biological Sciences
- Heavy Metal Exposure and Toxicity
- Sarcoidosis and Beryllium Toxicity Research
Zemun Hospital
2010-2025
University of Belgrade
2013-2024
University of Malta
2023
Institute of Virology, Vaccines and Sera “Torlak”
2016
Institut za filozofiju
2015-2016
University Hospital Centre Zagreb
2016
Kliničko Bolnički Centar Zvezdara
2012
University of Nis
2009
Institut za Reumatologiju
2008
The EFSA Panel on Food Additives and Nutrient Sources added to (ANS) provides a scientific opinion re-evaluating the safety of silicon dioxide (E 551) when used as food additive. forms synthetic amorphous silica (SAS) E 551 include fumed hydrated (precipitated silica, gel hydrous silica). Scientific Committee (SCF) established group acceptable daily intake (ADI) 'not specified' for silicates. SAS materials in available biological toxicological studies were different their physicochemical...
The present opinion deals with the re-evaluation of safety food-grade carrageenan (E 407) and processes Eucheuma seaweed 407a) used as food additives. Because structural similarities, Panel concluded that processed can be included in evaluation carrageenan. Poligeenan (average molecular weight 10-20 kDa) has not been authorised a additive is any applications. In its 407a), noted ADME database was sufficient to conclude absorbed intact; subchronic toxicity study performed almost complying EU...
The Panel on Food Additives and Nutrient Sources added to (ANS) provided a scientific opinion re-evaluating the safety of potassium nitrite (E 249) sodium 250) when used as food additives. ADIs established by SCF (1997) JECFA (2002) for were 0-0.06 0-0.07 mg/kg bw per day, respectively. available information did not indicate
The Panel on Food Additives and Nutrient Sources added to (ANS) provided a scientific opinion re-evaluating the safety of sodium nitrate (E 251) potassium 252) when used as food additives. current acceptable daily intakes (ADIs) for 3.7 mg/kg body weight (bw) per day were established by SCF (1997) JECFA (2002). available data did not indicate genotoxic potential nitrate. carcinogenicity studies in mice rats negative. considered derivation an ADI based formation methaemoglobin, following...
The Panel on Food Additives and Nutrient Sources added to (ANS) was asked deliver a scientific opinion the safety of monacolins in red yeast rice (RYR) provide advice dietary intake that does not give rise concerns about harmful effects health. reviewed evidences available as well information provided by interested parties response public 'Call for data' launched EFSA. considered monacolin K lactone form is identical lovastatin, active ingredient several medicinal products authorised...
The present scientific opinion deals with the evaluation of safety nisin (E 234) in light new toxicological data and proposed extension use unripened cheese heat-treated meat products. Nisin is currently an authorised food additive EU under Annex II Regulation (EC) 1333/2008 for several categories. as a has been evaluated 2006 by EFSA Panel on Food Additives, Flavourings, Processing Aids Materials Contact Food, where acceptable daily intake (ADI) 0.13 mg/kg body weight (bw) was confirmed...
The EFSA Panel on Food Additives and Nutrient Sources added to (ANS) provides a scientific opinion re-evaluating the safety of glutamic acid-glutamates (E 620-625) when used as food additives. Glutamate is absorbed in intestine it presystemically metabolised gut wall. No adverse effects were observed available short-term, subchronic, chronic, reproductive developmental studies. only effect was increased kidney weight spleen weight; however, increase organ not accompanied by histopathological...
Following a request from the European Commission, EFSA Panel on Food Additives and Nutrient Sources added to (ANS) was asked deliver scientific opinion re-evaluating safety of microcrystalline cellulose (E 460(i)), powdered 460(ii)), methyl 461), ethyl 462), hydroxypropyl 463), 464), 465), sodium carboxy 466), enzymatically hydrolysed 469) cross-linked 468) as food additives. The Joint FAO/WHO Expert Committee (JECFA) Scientific (SCF) established an acceptable daily intake (ADI) 'not...
The ANS Panel provides a scientific opinion re-evaluating the safety of glycerol (E 422) used as food additive. In 1981, Scientific Committee on Food (SCF) endorsed conclusion from Joint FAO/WHO Expert Additives (JECFA) in 1976 'acceptable daily intake (ADI) for man not specified'. concluded that has low acute toxicity and local irritating effects gastrointestinal tract reported some gavage studies was likely due to hygroscopic osmotic glycerol. Glycerol did raise concern with respect...
The present opinion deals with the re-evaluation of alginic acid and its sodium, potassium, ammonium calcium salts (E 400-E 404) when used as food additives. Alginic are authorised additives in EU accordance Annex II III to Regulation (EC) No 1333/2008. Following conceptual framework for risk assessment certain re-evaluated under Commission (EU) 257/2010, Panel concluded that there was no need a numerical Acceptable Daily Intake (ADI) 400, E 401, 402, 403 404), safety concern at level...
The Panel on Food Additives and Nutrient Sources added to (ANS) was asked deliver a scientific opinion the safety of hydroxyanthracene derivatives provide advice daily intake that does not give rise concerns about harmful effects health. Hydroxyanthracene are class chemical substances naturally occurring in different botanical species used food improve bowel function. ANS reviewed available data possible relationship between exposure genotoxic carcinogenic effects. On basis currently...
The Panel on Food Additives and Nutrient Sources added to (ANS) provides a scientific opinion re-evaluating the safety of xanthan gum (E 415) as food additive. Following conceptual framework for risk assessment certain additives re-evaluated under Commission Regulation (EU) No 257/2010, considered that adequate exposure toxicity data were available. Based reported use levels, refined up 64 mg/kg bw per day in children general population, 38 consumers only supplements at high level 115...
Abstract Introduction Echocardiography-derived septal strain patterns stages are associated with a stepwise increase in survival for each increment stage among patients treated cardiac resynchronization therapy (CRT). However, it is unknown whether the could also predict conservatively-treated (i.e. not CRT-implanted) patients. Purpose This study aims to investigate interplay between and long-term both CRT- Methods In this multicentre study, CRT-eligible from six European centres underwent...
The present opinion deals with the re-evaluation of lecithins (E 322) when used as a food additive. Lecithins is an authorised additive in EU according to Annex II and III Regulation (EC) No 1333/2008 on additives, have been previously evaluated by JECFA 1973 SCF 1982. Among lecithins, phosphatidylcholine hydrolysed choline cytidine-5-diphosphate-choline pathway all cells body. Following conceptual framework for risk assessment certain additives re-evaluated under Commission (EU) 257/2010,...
The EFSA Panel on Food Additives and Nutrient Sources added to (ANS) provides a scientific opinion re-evaluating the safety of b-cyclodextrin (E 459) as food additive.b-Cyclodextrin is non-reducing cyclic oligosaccharide consisting seven a-1,4-linked D-glucopyranosyl units.The Scientific Committee (SCF) allocated an acceptable daily intake (ADI) 5 mg/kg body weight (bw) per day in 1996.b-Cyclodextrin poorly absorbed following oral administration animals humans.It hydrolysed maltose glucose...
The EFSA Panel on Food Additives and Nutrient Sources added to (ANS) provides a scientific opinion re-evaluating the safety of mono- di-glycerides fatty acids (E 471) when used as food additive. considered that it is very likely hydrolysis by lipases in gastrointestinal tract would occur, resulting release glycerol acids. Glycerol 422) 570) have been re-evaluated concluded there was no concern regarding their use additives. Toxicological studies with rich unsaturated were for re-evaluation E...
The EFSA Panel on Food Additives and Nutrient Sources added to (ANS) provides a scientific opinion the refined exposure assessment of extracts rosemary (E 392) when used as food additive. Extracts was evaluated by AFC in 2008. Following this evaluation, authorised for use additive EU several categories with maximum levels. In 2015, ANS provided safety proposed extensions fat-based spreads. 2016, Joint FAO/WHO Expert Committee (JECFA) has established temporary acceptable daily intake (ADI)...
The EFSA Panel on Food Additives and Nutrient Sources added to (ANS) provides a scientific opinion re-evaluating the safety of fatty acids (E 570) when used as food additive. additive includes caprylic- (C8), capric- (C10), lauric- (C12), myristic- (C14), palmitic- (C16), stearic- (C18) oleic acid (C18:1), present alone or in combination. In 1991, Scientific Committee (SCF) established group acceptable daily intake (ADI) 'not specified' for (myristic, stearic, palmitic acid). are absorbed...
Following a request from the European Commission, EFSA Panel on Food Additives and Nutrient sources added to (ANS) was asked deliver scientific opinion re-evaluation of pectin (E 440i) amidated 440ii) as food additives. An acceptable daily intake (ADI) 'not specified' allocated by Scientific Committee for (SCF) E 440i 440ii. Pectin would not be absorbed intact, but extensively fermented intestinal microbiota in animals humans; products formed pectins gastrointestinal tract are similar...
The Panel on Food Additives and Nutrient Sources added to (ANS) provides a scientific opinion re-evaluating the safety of acacia gum (E 414) as food additive. In EU, has not been formally evaluated by Scientific Committee for (SCF), therefore, no ADI allocated. However, it was accepted use in weaning (SCF, 1991). 1999, SCF considered 'that gum/gum arabic coatings nutrient preparations containing trace elements is acceptable provided carry-over levels infant formulae, follow-on formulae or...
The Panel on Food Additives and Nutrient Sources added to (ANS) provides a scientific opinion re-evaluating the safety of polyglycerol polyricinoleate (PGPR, E 476) used as food additive. In 1978, Scientific Committee for (SCF) established an acceptable daily intake (ADI) 7.5 mg/kg body weight (bw) per day PGPR. PGPR is hydrolysed in gut resulting liberation free polyglycerols, polyricinoleic acid ricinoleic acid. Di- triglycerol are absorbed excreted unchanged urine; long-chain...
The European Commission requested EFSA to carry out a scientific evaluation on four studies the potential toxicity of titanium dioxide (TiO 2 ) used as food additive (E 171) and indicate whether they would merit re-opening existing opinion safety TiO additive.The results Bettini et al. ( 2017) study did not provide enough justification for new carcinogenicity study, but, should additional useful mechanistic information become available, this could be reconsidered in future.The vitro findings...