A5101412034- Cancer, Hypoxia, and Metabolism
- Phytochemical compounds biological activities
- Hypothalamic control of reproductive hormones
- Natural Compounds in Disease Treatment
- Cancer-related molecular mechanisms research
- Ovarian cancer diagnosis and treatment
- Cancer Cells and Metastasis
- Angiogenesis and VEGF in Cancer
- Artificial Intelligence in Healthcare and Education
- Toxin Mechanisms and Immunotoxins
- Circadian rhythm and melatonin
- Neuroendocrine regulation and behavior
- Simulation-Based Education in Healthcare
- Autophagy in Disease and Therapy
- Pharmacological Effects of Natural Compounds
- Estrogen and related hormone effects
- Silk-based biomaterials and applications
- Natural product bioactivities and synthesis
- Electrospun Nanofibers in Biomedical Applications
- Hepatitis C virus research
- Inflammatory mediators and NSAID effects
- Phytochemistry and Bioactive Compounds
- ATP Synthase and ATPases Research
- Immunotherapy and Immune Responses
- Cancer, Lipids, and Metabolism
Linyi People's Hospital
2023-2024
Thomas Jefferson University
2024
Inner Mongolia Medical University
2023
Xinjiang Medical University
2019-2021
Qufu Normal University
2014-2021
First Affiliated Hospital of Xinjiang Medical University
2019-2021
Southern University of Science and Technology
2019
Jinan University
2019
Harbin Medical University
2017-2018
Daqing City People's Hospital
2017-2018
Tumor metastasis is responsible for 90% of all cancer-related deaths. Epithelial to mesenchymal transition (EMT) an important prerequisite tumor metastasis. One the mediators EMT and cancer progression in ovarian vimentin protein. The objective current study was evaluate molecular mechanism that regulates expression cells. Vimentin robustly induced cell line SKOV-3 compared normal epithelial Moody induction not due transcriptional upregulation. Treatment with proteasomal inhibitor MG-132...
Abstract COX7A1 is a subunit of cytochrome c oxidase, and plays an important role in the super‐assembly that integrates peripherally into multi‐unit heteromeric complexes mitochondrial respiratory chain. In recent years, some researchers have identified implicated human cancer cell metabolism therapy. this study, we mainly explored effect on viability lung cells. overexpression was induced by vector transfection NCI‐H838 Cell proliferation, colony formation apoptosis were evaluated different...
Hepatocellular carcinoma (HCC) is identified as a common cancer type across the world and needs novel efficient treatment. Tripterine, well-known compound, exerts suppressive role in HCC development. However, related molecular mechanism of tripterine remains unclear. The expression MBNL1-AS1in tissues cells was measured via qRT-PCR assay. MTT assay employed to estimate cell viability. Besides, migration well invasion determined through transwell Additionally, binding ability miR-708-5p...
To date there has been no valid treatment for herpes simplex encephalitis (HSV). This study explores the protective activity of ethanol extract Cynanchum paniculatum (bunge) kitagawa HSV. Cell models and animal were established divided into 4 groups: normal group, virus cynanchum group Dexamethasone group. Flow cytometry was employed to detect apoptosis cell model TUNEL assay chosen tissues. The survival time observed. ELISA used measure TNF-alpha expression Greiss method Nitric Oxide (NO)...
Abstract Our earlier work has shown that the E3 ligase TRIM56 messenger RNA (mRNA) level and vimentin protein expression followed an inverse correlation in ovarian carcinoma patients; however, regulatory mechanisms underlying is unclear. Steady state of mRNA normal cell line Moody cancer lines SKOV‐3, A2780, Caov‐3 were not significantly different; was lower compared to line. Polysome profiling showed significant increase translation cells SKOV‐3 cells. We performed RNA‐affinity pulldown...
Background: E2F-mediated cell proliferation enhancing long noncoding RNA (EPEL) is an oncogenic (lncRNA) in lung cancer, but its involvement other malignancies unknown. We aimed at exploring the potential role of EPEL ovarian endometrioid adenocarcinoma. Results: Plasma levels and p53 were significantly upregulated adenocarcinoma patients. In effect, overexpression distinguished patients from control group. reversely correlated led to downregulated expression cells human line SNU-251,...
Abstract SLC7A5/LAT1 is a cross-membrane transporter that functions in uptake of large neutral amino acids into cells. Many pathological studies have shown LAT1 highly expressed cancer tissue from various origins such as lung, biliary tract, breast, prostate, bone, and their metastatic legions. High expression has been recognized significant prognostic marker cancers. Our TCGA data analysis showed the level higher TNBC tumors compared with normal breast tissues. The linked poor overall...
polyglycoside tablets (TWPT) have traditionally been used to treat certain inflammatory diseases. This study validated TWPT as a novel application in hepatocellular carcinoma treatment through multiple targets, thereby expanding its clinical medication scope. exhibited low toxicity and significantly antihepatoma effects
During a woman's reproductive period, the endometrial tissue is shed and regenerated every month to prepare for pregnancy or next cycle. The aim of present study was isolate, culture characterize human cells (ECs) derived from menstrual blood (MB) endometrium (E). MB-derived ECs (MB-ECs) were isolated women's MB. E-derived (E-ECs) tissues. investigated epithelial cell marker cytokeratin 18 (CK18) in MB-ECs E-ECs. Cell proliferation analyses indicated that E-ECs (population doubling time,...
The purpose of this study was to investigate the effect RFRP-3 synchronized with photoperiods on regulating seasonal reproduction striped hamsters. hamsters were raised separately under long-day (LD; 16 h light/8 dark), medium-day (MD; 12 light/12 dark) or short-day (SD; 8 light/16 conditions for weeks. and gonadotropin-releasing hormone (GnRH) mRNA levels in hypothalamus, testis ovaries three groups detected using reverse transcription polymerase chain reaction (RT-PCR). Melatonin (MLT),...