A5101564791- Nutrition, Genetics, and Disease
- HVDC Systems and Fault Protection
- Genomics and Rare Diseases
- Genomic variations and chromosomal abnormalities
- Cancer-related gene regulation
- RNA modifications and cancer
The Seventh Affiliated Hospital of Sun Yat-sen University
2023
Sun Yat-sen University
2023
Abstract The mechanism of m6A modification in HPV‐related cervical cancer remains unclear. This study explored the role methyltransferase components and mechanism. levels autophagy, ubiquitylation RBM15 protein co‐localization lysosomal markers LAMP2A were measured. CCK‐8 assay, flow cytometry, clone formation experiment immunofluorescence assay conducted to measure cell proliferation. mouse tumor model was developed growth vivo. binding c‐myc mRNA modifcation analyzed. expressions METTL3,...
Chromosomal karyotyping analysis has been considered as the gold standard for cytogenetic diagnosis and an effective measure preventing birth defects. However, conventional relies heavily on manual recognition, which is time-consuming labor-intensive. The application of efficient intelligent chromosomal precise auxiliary system in clinical practice can significantly reduce time greatly improve efficiency, increase detection rate low-percentage mosaicisms, promote homogenization between...