A5011233798- Antibiotic Resistance in Bacteria
- Mycobacterium research and diagnosis
- Enterobacteriaceae and Cronobacter Research
- Bacterial biofilms and quorum sensing
- Pharmaceutical and Antibiotic Environmental Impacts
- Molecular Biology Techniques and Applications
- RNA and protein synthesis mechanisms
- Plant Pathogenic Bacteria Studies
- Antibiotic Use and Resistance
- Mass Spectrometry Techniques and Applications
Second Affiliated Hospital of Soochow University
2022-2025
Soochow University
2022-2025
Central People's Hospital of Zhanjiang
2025
Abstract The indigenous microbial milieu within tumorous tissues exerts a pivotal influence on the genesis and advancement of gastric cancer (GC). This investigation scrutinizes functions molecular mechanisms attributed to Prevotella intermedia in malignant evolution GC. Isolation P. from paired GC was undertaken. Quantification abundance 102 accomplished using quantitative real‐time PCR (qRT‐PCR). Assessment biological effects cells observed culture medium supernatant. Furthermore, protein...
Objectives The aim of this study is to characterize the genomic features ST6115 carbapenem-resistant Klebsiella pneumoniae (CRKP) co-harboring bla NDM-1 and IMP-4 . Methods genome sequences one (KP) strain 12 ST17 KP were obtained through whole sequencing (WGS). Subsequently, a phylogenetic analysis was employed ascertain clonal relationship these strains. antimicrobial susceptibility testing (AST) evaluated application minimum inhibitory concentration (MIC) methodology by broth...
Epidemiological characteristics and molecular features of carbapenem-resistant Enterobacter (CR-Ent) species remain unclear in China. In this study, we performed a genomic study on 92 isolates from Enterobacter-caused infections multicenter Whole genome sequencing (WGS) was used to determine the sequence non-duplicated CR-Ent strains collected multiple tertiary health centres. The precise were identified by average nucleotide identity (ANI) silico DNA–DNA hybridization (isDDH). Molecular...
ABSTRACT The resistance mechanism of Gram-negative bacteria to the siderophore antibiotic cefiderocol is primarily attributed carbapenemase and uptake pathways; however, specific factors their relationships remain be fully elucidated. Here, we constructed cefiderocol-resistant Klebsiella pneumoniae (CRKP) strains carrying different carbapenemases knocked out genes investigate roles various siderophores in development resistance. Antimicrobial susceptibility testing revealed that both bla NDM...