A5054095890- Burn Injury Management and Outcomes
- Wound Healing and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Sarcoma Diagnosis and Treatment
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Neuroscience and Neural Engineering
- Autoimmune Bullous Skin Diseases
- Muscle activation and electromyography studies
- Bone fractures and treatments
- Drug-Induced Adverse Reactions
- Anesthesia and Pain Management
- Reconstructive Facial Surgery Techniques
- Blood transfusion and management
- Cardiac tumors and thrombi
- Planarian Biology and Electrostimulation
- Facial Nerve Paralysis Treatment and Research
- Hernia repair and management
- Urological Disorders and Treatments
- Muscle and Compartmental Disorders
- Erythropoietin and Anemia Treatment
- Electrolyte and hormonal disorders
- Hip and Femur Fractures
- Orthopedic Surgery and Rehabilitation
- Acute Kidney Injury Research
- Tissue Engineering and Regenerative Medicine
Carol Davila University of Medicine and Pharmacy
2016-2025
Clinical Emergency Hospital Bucharest
2016-2025
Center For Reconstructive Urethral Surgery
2018-2019
Background and Objectives: Burn patients manifest all components of Virchow’s triad, amplifying the concern for venous thromboembolism (VTE). Routine prophylaxis VTE remains a subject debate, with central being occurrence associated adverse events. Materials Methods: We conducted five-year retrospective study on burn admitted to our center. Demographic data, comorbidities, lesions characteristics, surgical interventions, anticoagulant medication, need transfusions, presence catheter, length...
Background and objectives: Burn injuries are the most severe type of trauma, with complex biological consequences associated high rates morbidity mortality. Prompt recognition management burn-related complications imperative for improving vital functional prognosis patient. Changes in parameters can be essential determinants burned Thrombocytopenia critically ill patients is linked to an elevated risk We sought investigate significance thrombocytopenia severely while considering limited...
Toxic epidermal necrolysis (TEN) is a serious dermatological condition often triggered by different drugs or medications or, less commonly, infections, leading to extensive detachment and multisystemic complications, resembling the severity systemic impact of burn injuries. This case report portrays 26-year-old female patient with history psychiatric treatment recreational drug use, presenting typical prodromal symptoms characteristic manifestations on integument mucosae. Clinical management...
Burn injuries rank among the most severe forms of trauma, posing a significant global public health challenge due to their high morbidity and mortality, even within specialised burn care facilities. Effective treatment for burns necessitates comprehensive critical early identification complications, which can improve patient survival functionality. A set criteria has been established admitting patients centres, ensuring that those with extensive, complex, or specific types receive...
Chronic liver diseases are a public health issue, because of their high incidence and prevalence, the important impact on quality life mortality rates. From pathogenic point view, in almost all there is an increase oxidative stress. Oxidative stress represents as imbalance between production oxidizing agents antioxidants. This contributes to initiation progression hepatic injury. Among most risk factors for increased chronic alcohol, drugs, environmental pollutants irradiation. For...
Mitocurcumin (a triphenylphosphonium curcumin derivative) was previously reported as a selective antitumoral compound on different cellular lines, well potent bactericidal candidate. In this study, the same showed strong antimicrobial efficacy against strains of methicillin-resistant Staphylococcus aureus (MRSA). The minimum inhibitory concentration identical for all tested (four MRSA and one strain methicillin-sensitive aureus), suggesting new mechanism action compared with usual...
Pain is a very important issue to take into account during hospitalization. Nefopam, centrally acting analgesic, has relative safety pharmacological profile with few and well-tolerated side effects, being used treat acute or chronic pain. It inhibits the central reuptake of serotonin, norepinephrine dopamine modulates sodium calcium channels having only contraindications. Nefopam can be part balanced analgesia along others non-opioids agents in order reduce opioid consumption their...
Atrial fibrillation is a commonly encountered pathology in medical practice, and its prevalence has shown continuous rise over the past years. significant impact on patients' quality of life, not only due to standard anticoagulant treatment with vitamin K antagonists that require close monitoring dose adjustment, but also fragile equilibrium between hemorrhagic thrombotic risks. The introduction new oral anticoagulants (NOACs) guidelines for atrial improved as NOACs do or adjustments....
There is great interest in the development of prosthetic limbs capable complex activities that are wirelessly connected to patient’s neural system. Although some progress has been achieved this area, one main problems encountered selective acquisition nerve impulses and closing automation loop through stimulation sensitive branches patient. Large-scale research have so-called “cuff electrodes”; however, they present a big disadvantage: not selective. In article, we made an implantable system...
Burns, one of the main public health problems, lead to significant mortality and morbidity. Epidemiological studies regarding burn patients in Romania are scarce. The aim this study is identify etiology, demographics, clinical characteristics, outcomes requiring treatment a regional unit. We performed retrospective observational 2021. All admitted our six-bed intensive care unit (ICU) were included. following data collected for further analysis: pattern (etiology, size, depth, affected body...
Retroperitoneal space is called sometimes no man�s land�and for a good reason: this disputed anatomical territory many surgical and medical specialties. Their wide histological diversity unspecific clinical presentation make them challenge the surgeon. In order to improve their detection immunohistochemistry seems show promising results. Methods of have evolved over time identify as much possible type tumor. Because extreme variability through its various markers one that often sets...
Abstract The development of stem cell technology in combination with advances biomaterials has opened new ways producing engineered tissue substitutes. In this study, we investigated whether the therapeutic potential an acellular porous scaffold made type I collagen can be improved by addition a powerful trophic agent form mesenchymal stromal cells conditioned medium (MSC‐CM) order to used as for skin wound healing treatment. Our experiments showed that MSC‐CM sustained adherence...
Castleman�s disease (CD) is a rare and benign lymphoproliferative pathology, characterized by lymphoid tissue hyperplasia, process that can occur at any site of the chain. The purpose this paper to review existing data regarding etiopathogenesis treatment. Considering extent involvement be classified as unicentric (UCD) multicentric (MCD). Another classification pathology based on histopathological features: hyaline vascular CD (90% cases), plasma cell (less than 10%) mixed type. Patients...
Adipose-derived mesenchymal stromal cells (ADSC) are a promising source for cellular therapy of chronic wounds. However, the limited life span during in vitro expansion impedes their extensive use clinical applications and basic research. We hypothesize that by introduction an ectopic expression telomerase into ADSC, cells' lifespans could be significantly extended. To test this hypothesis, we aimed at engineering immortalized human ADSC line using lentiviral transduction with (hTERT). were...