A5044434582- Acute Myeloid Leukemia Research
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Viral-associated cancers and disorders
- Multiple Myeloma Research and Treatments
- Chronic Myeloid Leukemia Treatments
- Science Education and Pedagogy
- Bone health and treatments
- Acute Lymphoblastic Leukemia research
- Histiocytic Disorders and Treatments
- Cutaneous lymphoproliferative disorders research
- Educational Strategies and Epistemologies
- T-cell and Retrovirus Studies
- Hematological disorders and diagnostics
- Innovative Teaching and Learning Methods
- CNS Lymphoma Diagnosis and Treatment
- CAR-T cell therapy research
- Parvovirus B19 Infection Studies
- Animal and Plant Science Education
- Eosinophilic Disorders and Syndromes
- Genetic factors in colorectal cancer
- Genetic and Kidney Cyst Diseases
- Cancer Genomics and Diagnostics
- Histone Deacetylase Inhibitors Research
Emory University
2020-2024
Roche (Switzerland)
2022
University of Alabama at Birmingham
2013-2019
University of Colorado Denver
2019
University of Colorado Cancer Center
2019
O'Neal Comprehensive Cancer Center
2019
Columbus State University
2012-2014
University of South Florida
2012-2013
Florida College
2012-2013
Moffitt Cancer Center
2011-2012
Acute myeloid leukemia (AML) is the most common form of acute among adults and accounts for largest number annual deaths due to leukemias in United States. This portion NCCN Guidelines AML focuses on management provides recommendations workup, diagnostic evaluation, treatment options younger (age <60 years) older ≥60 adult patients.
Acute myeloid leukemia (AML) is the most common form of acute among adults and accounts for largest number annual deaths due to leukemias in United States. Recent advances have resulted an expansion treatment options AML, especially concerning targeted therapies low-intensity regimens. This portion NCCN Clinical Practice Guidelines Oncology (NCCN Guidelines) AML focuses on management provides recommendations workup, diagnostic evaluation younger (age <60 years) older ≥60 adult patients.
Multiple myeloma (MM) cells reside in the bone marrow microenvironment and form complicated interactions with nonneoplastic, resident stromal cells. We previously found that aggressive MM shift osteoblast progenitors toward adipogenesis. In addition, adipocytes are among most common cell types adult skeleton; both mature preadipocytes serve as endocrine secrete a number of soluble molecules into microenvironment. Therefore, we used combination vivo vitro methods to test hypothesis an...
The outcomes of patients with DLBCL and primary treatment failure (PTF) in the rituximab era are unclear. We analyzed 331 PTF, defined as progression while on upfront chemoimmunotherapy (PP), residual disease at end therapy (RD) or relapse < 6 months from (early relapse; ER). Median age was 58 years response to salvage 41.7%. Two-year OS 18.5% PP, 30.6% RD 45.5% ER. presence intermediate-high/high NCCN-IPI time PTF MYC translocation predicted 2-year 13.6% constituting ultra-high risk (UHR)...
Chronic myelomonocytic leukemia (CMML), a clonal hematopoietic stem cell disease, may be linked to immune-mediated processes and/or autoimmune disorders (AID), although the exact pathogens are still elusive. We retrospectively analyzed 123 CMML patients in our institution. Twenty-four (19.5%) had at least one disorder, most commonly idiopathic thrombocytopenic purpura, gout and psoriasis. Four of these 24 (15%) more than AID. found that, contrast general population with prevalence rate...
This study compared students' perceptions of doing science and scientists reflected in their drawings using a modified version the Drawing-A-Scientist-Test across five different countries: China, India, South Korea, Turkey, US. The participants were 1,800 students from grades three, seven ten countries. Thirty randomly selected interviewed semi-structured interview protocol. Results indicated that fewer stereotypes exhibited at lower than higher all Students US, Korea perceived passive more...
Abstract Objectives T-cell prolymphocytic leukemia (T-PLL) is a rare mature usually characterized by inv(14)(q11.2q32)/t(14;14)(q11.2;q32). In this study, we aimed to investigate the clinicopathologic features and molecular profile of T-PLL associated with t(X;14)(q28;q11.2). Methods The study group included 10 women 5 men median age 64 years. All 15 patients had diagnosis Results lymphocytosis at initial diagnosis. Morphologically, leukemic cells prolymphocytes in 11 patients, small cell...
Aims Myeloid sarcoma (MS) is a rare extramedullary neoplasm composed of immature myeloid precursor cells thought to be unique clinical presentation acute leukaemia (AML). Like AML, MS has poor prognosis, but due the nature there are limited studies examining potential prognostic factors. We report our institutional experience, with aim investigating and establishing salient clinicopathological molecular features MS. Methods results retrospectively examined all data on patients between 2001...
Many science education programs involve scientists in K-12 to support students’ engagement scientific practices and learning process skills epistemologies. Little research has studied the actions of classrooms or how scientists’ may (or not) supplement complement teachers. In this descriptive study, we explore teachers scientists, working pairs, guide high school students practice experimentation. particular, study ways by which act independently concert designing conducting biology...
Grading of pancreatic neuroendocrine tumors (pNETs) is currently based on mitotic rate and Ki67 proliferation index. Phosphohistone-H3 (PHH3) an effective marker for mitosis that has been proposed to use in grading various NETs. It remains unclear which method more accurately predicts grade clinical outcome. Cases pNET were evaluated using immunohistochemical stains PHH3. In addition, each case was necrosis, lymphovascular invasion, perineural invasion compared with stage. R project...
// Juan Li 1, 2, * , Qianying Pan Patrick D. Rowan Timothy N. Trotter 1 Deniz Peker Kellie M. Regal Amjad Javed 3, 4 Larry J. Suva 5 Yang 3 Department of Pathology, University Alabama at Birmingham, AL, USA 2 Hematology, the First Affiliated Hospital Sun Yat-Sen University, Guangdong, China Comprehensive Cancer Center and for Metabolic Bone Disease, Oral Maxillofacial Surgery, School Dentistry, Veterinary Physiology Pharmacology, College Medicine Biomedical Sciences, Texas A & M Station, TX,...