- Thyroid Cancer Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Thyroid and Parathyroid Surgery
- Adrenal and Paraganglionic Tumors
- Growth Hormone and Insulin-like Growth Factors
- Head and Neck Anomalies
- Vitamin D Research Studies
- Parathyroid Disorders and Treatments
- BRCA gene mutations in cancer
- Neuroendocrine Tumor Research Advances
- Thyroid Disorders and Treatments
- Hormonal Regulation and Hypertension
- Adrenal Hormones and Disorders
- Bone health and osteoporosis research
- Bone health and treatments
- Meningioma and schwannoma management
- Biomarkers in Disease Mechanisms
- Genetic Syndromes and Imprinting
- Hormonal and reproductive studies
- Birth, Development, and Health
- Clay minerals and soil interactions
- Electrolyte and hormonal disorders
- Heavy metals in environment
- Radiation Dose and Imaging
- Sustainable Development and Environmental Policy
Rabin Medical Center
2015-2024
Tel Aviv University
2013-2023
Institute of Endocrinology
2016-2023
Maccabi Health Care Services
2013-2022
Clalit Health Services
2021
Endocrine Society
2013
Pennsylvania Hospital
1998-1999
Winthrop-University Hospital
1998-1999
Hebrew University of Jerusalem
1989-1992
Evaluation of surgical specimens suggests that patients with Hashimoto thyroiditis (HT) have a higher prevalence differentiated thyroid cancer. Although HT are reported to present earlier stage disease, there is controversy as whether these better prognosis when adjusted for histology and at presentation. To investigate differences between cancer without aggressiveness disease clinical outcome, the decline rate antithyroglobulin antibodies titers over time. A retrospective study using Rabin...
Primary hyperparathyroidism (PHPT) during pregnancy may pose considerable risks to mother and fetus. This study examined outcomes in women with gestational PHPT relation clinical laboratory parameters.This was designed as a retrospective case series.The group included 74 aged 20-40 years who were diagnosed after finding of serum calcium ≥ 10.5 mg/dL on routine screening at health maintenance organization (2005-2013) became pregnant the time hypercalcemia (124 pregnancies). Clinical data...
Familial nonmedullary thyroid cancer (FNMTC) is a disease defined by clustering of cancers follicular cell origin, and it estimated to account for 5% all cancers. Several studies found FNMTC be more aggressive than sporadic disease, whereas others them have similar course outcome. The purpose this study was determine whether cancer.A retrospective controlled versus conducted using registry patients with cancer. Data on severity at presentation, treatment modalities, outcome were...
Abstract Background Minimal extrathyroid extension (mETE) in patients with differentiated thyroid cancer (DTC) was defined as an intermediate risk feature the 2015 American Thyroid Association guidelines. However, controversy persists several studies suggested mETE has little effect on disease outcome. Objective To assess impact of DTC patients' Methods Meta-analysis controlled trials comparing and without mETE. Data Extraction Synthesis Thirteen retrospective including 23,816 were included,...
Abstract Background The use of thyroglobulin (Tg) and antibodies (TgAb) for detecting disease recurrence is well validated following total thyroidectomy radioiodine ablation. However, limited data are available patients treated with thyroid lobectomy. Methods Patients who had lobectomy papillary cancer followed >1 year, sufficient on Tg TgAb, including subgroup analysis Hashimoto’s thyroiditis contralateral nodules. Results One-hundred sixty-seven met the inclusion criteria. Average...
Hypothyroidism during pregnancy has been associated with adverse obstetrical outcomes. Most studies have focused on subjects a mild or subclinical disorder. The aims of the present study were to determine relative rate severe thyroid dysfunction among pregnant women hypothyroidism, identify related factors and analyse impact outcomes.A retrospective case series design was employed.The group included 101 (103 pregnancies) an antenatal serum TSH level >20.0 mIU/l identified from 2009-2010...
Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy. Despite its low mortality rate, disease has a recurrence rate of up to 30%. The mainstay treatment for PTC surgery, followed by radioiodine ablation and thyroxine therapy in appropriately selected patients. can appear as unifocal solitary tumor, but also two or more anatomically separate foci. A great deal controversy surrounds significance multifocality prognostic factor, it considered poor factor that prompts...
Abstract Effects of inorganic complexation in solution, ionic strength, and clay concentration on Cd adsorption to montmorillonite were investigated. Increased strength decreases adsorption. The presence a complexing anion such as Cl ‐ inhibits When the was HCO 3 , disappearance from equilibrium solution enhanced compared case where ClO 4 which does not form complexes with Cd. explanation latter phenomenon is still incomplete, two possibilities being either strong binding complex CdHCO + or...
Abstract Total Cd concentration was measured in the saturation extract of three unpolluted arid‐zone forest soils to which added as Cd(NO 3 ) 2 solution (0.1 mg kg −1 soil). The ratio free total (Cd 2+ /Cd t extracted soil using a selective electrode by an addition method. A chemical equilibrium model including major complexation reactions with anionic llgands used estimate speciation and validated agreement between calculated ratios. Free CdHCO + were each estimated constitute 35% 45%,...
Patients with differentiated thyroid cancer (DTC) usually have a good prognosis but may experience decline in quality of life (QOL). The way patients perceive their illness major impact on QOL. Our hypothesis was that DTC frequently as much more severe than its objective clinical characteristics indicate. aim the study to investigate how and correlate these findings various demographic parameters well indices disease severity.The self-administered Illness Perception Questionnaire-Revised...
Papillary thyroid cancer (PTC) commonly affects women of child-bearing age. During normal pregnancy, several factors may have a stimulatory effect on and nodular growth. The aim the study was to determine whether pregnancy in thyroid-cancer survivors poses risk progression or recurrence disease.The files 63 consecutive who were followed at Endocrine Institute for PTC 1992-2009 had given birth least once after receiving treatment reviewed clinical, biochemical, imaging data. Thyroglobulin...
The aim of the present study was to investigate differences in quality life (QOL) following complete or partial thyroidectomy and with regard thyroid hormone replacement (LT4) therapy.Patients who underwent were asked validated thyroid-specific ThyPRO QOL questionnaire at least 6 months surgery.Tertiary medical center.Thyroid specific analysis.A total 190 patients completed questionnaire. Of them 89 had 101 unilateral lobectomy. group significantly worse overall self-assessment score than...
Abstract The adsorption of Li, Na, K, Cs, and Sr to montmorillonite is studied within the framework a model that accounts for specific binding as well in double layer region. Variations solution concentrations cations due are explicitly considered. experimental data include measurements binary ternary systems taken from literature. Solution adsorbed simulated predicted by calculations wide range variations cation ratios, ionic strengths, clay concentrations. values determined coefficients...
Abstract Context: There is no therapy for control of hypercalciuria in nonoperable patients with primary hyperparathyroidism (PHPT). Thiazides are used idiopathic but avoided PHPT to prevent exacerbating hypercalcemia. Nevertheless, several reports suggested that thiazides may be safe PHPT. Objective: To test the safety and efficacy Design: Retrospective analysis medical records. Setting: Endocrine clinic at a tertiary hospital. Patients: Fourteen male 58 female treated thiazides....
Background: The occurrence of nonthyroidal primary malignancy (NTPM) and the potential association with radioiodine (RAI) treatment are important concerns in patients differentiated thyroid cancer (DTC), but incidence data conflicting. aims present study were to investigate NTPM its RAI a cohort DTC treated at single tertiary medical center. Methods: 1943 recorded Rabin Medical Center Thyroid Cancer Registry cross-matched from Israeli National identify those diagnosed an NTPM. Patient files...
Background: The extent of surgery for differentiated thyroid cancer (DTC) remains a controversial issue. Since less aggressive approach is becoming more predominant, we aim here to study the short- and long-term outcomes DTC patients after hemithyroidectomy. Methods: From total 1252 consecutive papillary (PTC) patients, 109 treated with hemithyroidectomy 50 thyroidectomy but no I131 were included. Persistent or recurrent disease was defined based on histopathology, imaging studies,...