A5071259640- Bacteriophages and microbial interactions
- Antibiotic Resistance in Bacteria
- Bacterial Genetics and Biotechnology
Newcastle University
2021-2023
Gram-positive bacterial cells are protected from the environment by a cell envelope that is comprised of thick layer peptidoglycan maintains shape and teichoic acid polymers whose biological function remains unclear. In Bacillus subtilis, loss all class A penicillin-binding proteins (aPBPs), which in synthesis, conditionally lethal. Here, we show this lethality associated with an alteration lipoteichoic acids (LTAs) accumulation major autolysin LytE wall. Our analysis provides further...
Abstract Gram-positive bacterial cells are protected from the environment by a cell envelope which comprises of layers peptidoglycan that maintain shape and teichoic acids polymers whose biological function remains unclear. In Bacillus subtilis , loss all Class A Penicillin-Binding Proteins (aPBPs) in synthesis is conditionally lethal. Here we show this lethality associated with an alteration lipoteichoic (LTA) accumulation major autolysin LytE wall. Our analysis provides further evidence...