A5003155435- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Retinal Development and Disorders
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiovascular Syncope and Autonomic Disorders
- Retinal Diseases and Treatments
- ECG Monitoring and Analysis
- Dialysis and Renal Disease Management
- Genetics, Aging, and Longevity in Model Organisms
- Management of metastatic bone disease
- Cancer Treatment and Pharmacology
- Peripheral Nerve Disorders
- Pharmaceutical Economics and Policy
- Urinary Bladder and Prostate Research
- Moyamoya disease diagnosis and treatment
- Pharmaceutical industry and healthcare
- Aging, Health, and Disability
- Angiogenesis and VEGF in Cancer
- Health and Lifestyle Studies
- Cardiac Structural Anomalies and Repair
- Renal and Vascular Pathologies
- Aortic aneurysm repair treatments
- Sexual function and dysfunction studies
- Retinopathy of Prematurity Studies
- Hormonal and reproductive studies
Universidad Pontificia Bolivariana
2015-2022
Universidad de Antioquia
2019-2022
Kingston Health Sciences Centre
2022
Hospital Pablo Tobon Uribe
2022
Hospital Universitario de San Vicente Fundación
2019
Massachusetts Eye and Ear Infirmary
2017
Smith-Kettlewell Eye Research Institute
2017
Harvard University
2017
Municipality of Medellín
2016
Proliferative diabetic retinopathy (PDR) is a common cause of blindness in the developed world’s working adult population and affects those with type 1 2 diabetes. We identified Runt-related transcription factor (RUNX1) as gene upregulated CD31+ vascular endothelial cells obtained from human PDR fibrovascular membranes (FVMs) via transcriptomic analysis. In vitro studies using retinal microvascular (HRMECs) showed increased RUNX1 RNA protein expression response to high glucose, whereas...
Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a neurological syndrome characterized by small vessel disease (SVD), stroke, vascular cognitive impairment dementia caused mutations in NOTCH3 No therapies are available for this condition. Loss of mural cells, which encompass pericytes smooth muscle hallmark CADASIL other SVDs, including diabetic retinopathy, resulting instability. Here, we showed that Notch3 signaling both necessary...
In recent years there has been a marked increase in the proportion of population over 65 age, which gone hand with escalation cardiovascular diseases, particularly coronary disease. However, pathophysiological mechanisms aging and its relationship to health is field research. It fundamental know aspects such as theory telomere shortening, role physical activity, endothelium molecular involved this process, they will offer tools for correct management group, upon few studies are carried out...
To describe the clinical characteristics and cardio-oncological assessment in patients undertaking highly toxic chemotherapy and/or chest radiotherapy a high-complexity hospital.A single-center retrospective cohort study was carried out between January 1st, 2017 December 31st, 2019. The medical records of with solid or hematological neoplasms were reviewed. Descriptive information obtained on demographic characteristics, chemotherapeutic agents, pre-chemotherapy cardiovascular (CV)...
Resumen El adulto mayor se encuentra en una etapa de la vida con cambios fisiologicos importantes que posee repercusiones directas e indirectas sobre su estado clinico, es asi como el enfoque diagnostico y terapeutico sus patologias debe ser abordado desde perspectiva diferente, consideraciones especiales para este grupo poblacional. Lamentablemente, no ha sido bien representado los diferentes estudios por tanto, mucho lo desconocemos; comportamiento eficacia las distintas terapias estan...
Resumen La poblacion de adultos mayores ha tenido muy poca representacion en los diferentes estudios clinicos, afectando el conocimiento sobre tratamiento adecuado este grupo etario. Las determinaciones excluir a tipo dichos se hacen basadas un incremento la probabilidad presentar eventos adversos, aumentando complejidad del analisis resultados. Se hace necesario utilizar escalas validas que permitan evaluar verdadero riesgo estos pacientes para desarrollar complicaciones secundarias...
Erectile dysfunction (ED) is a common disorder whose prevalence increases with age.Over time strong correlation between erectile and cardiovascular disease has been established as the result of same pathophysiological process: endothelial atherosclerosis.Because small vessels penis can be affected by atherosclerotic plaque earlier than coronary arteries, carotids or femoral men often have symptoms ED long before signs appear.For this reason, act marker early atherosclerosis that predicts...
Hipertensión arterial; Ablación con catéter; refractaria
Electrocardiogram is a useful tool for the diagnosis of acute coronary syndrome. In recent years, ST-segment changes in aVR have been shown to provide valuable information about anatomy and early risk stratification this condition.
REVISIÓN ResumenLa presencia de un bloqueo rama izquierda del haz His nuevo o presumiblemente junto con síntomas isquémicos se ha considerado tradicionalmente
Abstract Introduction Cardiovascular disease is the main cause of death in world, cancer represents an increasing problem and second leading globally. Survival patients with has increased, cardiovascular survivors morbidity secondary to toxicity issue concern. We aimed describe clinical characteristics cardio-oncologic assessment receiving high chemotherapy. Methods Retrospective unicentric cohort study between January 1st, 2017 December 31st, 2019, all medical records from solid or...