Zhenzhou Li

ORCID: 0000-0002-4385-3498
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About
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Research Areas
  • Heat Transfer and Optimization
  • Heat Transfer Mechanisms
  • Ultrasound and Hyperthermia Applications
  • Photoacoustic and Ultrasonic Imaging
  • Cardiovascular Health and Disease Prevention
  • Cerebrovascular and Carotid Artery Diseases
  • Nanoplatforms for cancer theranostics
  • Hydrocarbon exploration and reservoir analysis
  • Nanofluid Flow and Heat Transfer
  • Cardiovascular Disease and Adiposity
  • Heat Transfer and Boiling Studies
  • Anesthesia and Pain Management
  • Anesthesia and Sedative Agents
  • Anesthesia and Neurotoxicity Research
  • Cancer Research and Treatments
  • Ultrasound Imaging and Elastography
  • RNA modifications and cancer
  • Hemodynamic Monitoring and Therapy
  • Cardiovascular Function and Risk Factors
  • Cardiac Imaging and Diagnostics
  • Cancer-related molecular mechanisms research
  • Heart Rate Variability and Autonomic Control
  • Geological Modeling and Analysis
  • Reservoir Engineering and Simulation Methods
  • Liver Disease Diagnosis and Treatment

Guangxi University
2022-2025

Shenzhen Second People's Hospital
2013-2025

Guangxi University of Chinese Medicine
2024-2025

Harbin Institute of Technology
2025

Sun Yat-sen Memorial Hospital
2025

Sun Yat-sen University
2025

Hohai University
2024

Shenzhen University Health Science Center
2022-2023

Ningxia Medical University
2010-2023

Zhengzhou University
2023

Abstract Epithelial mesenchymal transition (EMT) of tumor cells is recognized as the main driver to promote metastasis. Extensive researches suggest that gradually decreased E‐cadherin (E‐cad) and increased N‐cadherin (N‐cad) exist in during EMT process. However, there still lacks suitable imaging methods monitor status for evaluating metastatic potentials. Herein, E‐cad‐targeted N‐cad‐targeted gas vesicles (GVs) are developed acoustic probes tumor. The resulting have ≈200 nm particle size...

10.1002/smll.202207940 article EN Small 2023-03-03

Common buckwheat is a health-care crop, and continuous cropping one of the main factors restricting its high-yielding. In order to clarify mechanism buckwheat, 4, 5and 6 years treatments were set up. We obtained following results. The available nutrients content in rhizosphere soil, soil enzyme activity, leaf area, chlorophyll soluble protein content, peroxidase(POD) activity leaves, agronomic traits, root index (except average diameter) Fengtian1(FT1) decreased significantly with increase...

10.1080/1343943x.2019.1685895 article EN cc-by-nc Plant Production Science 2019-10-31

Osteosarcoma is the most common primary malignant tumor of bone. However, there a lack effective means for early diagnosis due to heterogeneity tumors and complexity microenvironment. αvβ3 integrin, crucial role in growth spread tumors, not only an biomarker cancer angiogenesis, but also highly expressed many cells. Here, we selected it as imaging target fabricated iRGD-sGVs acoustic probe early-stage osteosarcoma. Biological nanoscale gas vesicles (sGVs) were extracted from Serratia 39006....

10.2147/ijn.s494151 article EN cc-by-nc International Journal of Nanomedicine 2025-01-01

Ultrasound (US)-guided percutaneous lumbar plexus block (LPB), enhanced by ultrasound-computed tomography (US-CT) fusion imaging, offers precise targeting for interventions. In this case, a patient with disk herniation at L4–L5 level, who had undergone pedicle screw internal fixation, continued to experience persistent low back pain and numbness in both lower limbs. US-CT fusion-guided medial branch level significantly alleviated symptoms within 24 hours, sustained relief 1 month....

10.1213/xaa.0000000000001930 article EN A&A Practice 2025-04-01

Abstract Ultrasound molecular imaging (UMI) has shown promise for assessing the expression levels of biomarkers early detection various diseases. However, it remains difficult to simultaneously image multiple in a single systemic administration, which is important accurate diagnosis diseases and understanding dynamic intermolecular mechanisms that drive their malignant progression. The authors develop an ultrasound method by serial collapse targeting microbubbles with distinct acoustic...

10.1002/smll.202108040 article EN Small 2022-05-02

Fibrotic tissue remodelling in nonalcoholic fatty liver disease (NAFLD) will probably emerge as the leading cause of end-stage coming decades, but ability to diagnose fibrosis NAFLD patients noninvasively is limited. The abnormal expression tRNA-derived small RNA (tsRNA) plasma provides a novel idea for noninvasive diagnosis various diseases, however, relationship between tsRNAs and still unknown. Here, we took advantage RNA-Seq technology profile found ubiquitous presence hepatic secreted...

10.1038/s41598-021-85421-0 article EN cc-by Scientific Reports 2021-03-15

Atherosclerosis is the main risk factor for cardiovascular disease, which accounts majority of mortality worldwide. A significantly increased plasma level low-density lipoprotein cholesterol (LDL-C), surrounded by a monolayer phospholipids, free cholesterol, and one apolipoprotein B-100 (ApoB-100) in blood, plays most significant role driving development atherosclerosis. Commercially available cholesterol-lowering drugs are not sufficient preventing recurrent events. Developing alternative...

10.1021/acsami.4c00999 article EN ACS Applied Materials & Interfaces 2024-05-03

Neurovascular coupling, the process by which neuronal activity elicits increases in local blood supply, is impaired stroke patients brain regions outside infarct. Such impairment may contribute to neurological deterioration over time, but its mechanism unknown. Using middle cerebral artery occlusion (MCAO) model of stroke, we show that activity-evoked capillary dilation reduced ∼75% intact cortical tissue infarct border. This decrease responsiveness was not explained a or loss vascular...

10.3389/fncel.2021.762843 article EN cc-by Frontiers in Cellular Neuroscience 2021-11-08

Abstract Study Objective Prophylactic norepinephrine infusion effectively lowers the incidence of postspinal anesthesia hypotension. The optimal prophylactic dose remains undefined. purpose this study was to investigate prevent hypotension in patients undergoing cesarean section. Design Prospective, double‐blind, randomized, controlled, dose‐finding trial. Setting Operating room from March 2020 June 2020. Patients Ninety nine primipara or multipara women 18 ‐ 40 years age, singleton...

10.1002/phar.2514 article EN Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy 2021-02-14

Objective: To evaluate the relationship between contrast-enhanced ultrasonography (CEUS) of carotid intraplaque neovascularization and ischemic stroke in transient attack (TIA) patients. Methods: A total 112 TIA patients were selected for study. Routine ultrasonic examination was performed all CEUS carried out consecutive with plaque thicker than 2.5 mm bifurcation follow-up at least 24 months. The number incurrence or recurrence obtained during period. detect risk factors months,...

10.3389/fphar.2019.00672 article EN cc-by Frontiers in Pharmacology 2019-06-21

In this paper, the authors' goal was to demonstrate clinical and technical nuances of a minimally invasive lateral extracavitary approach (MI-LECA) for thoracic corpectomy anterior column reconstruction.A cadaveric feasibility study subsequent application in 3 cases are reported. Six procedures were completed human cadavers. Minimally invasive, extrapleural corpectomies performed with aid 24-mm tubular retraction system, using posterolateral incision an oblique angle. Fluoroscopy...

10.3171/2012.2.spine11128 article EN Journal of Neurosurgery Spine 2012-03-09
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