A5033838223- Sarcoma Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- COVID-19 Clinical Research Studies
- Tumors and Oncological Cases
- Neonatal Respiratory Health Research
- Testicular diseases and treatments
- Anesthesia and Pain Management
- Lymphoma Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Retinopathy of Prematurity Studies
- COVID-19 diagnosis using AI
- Urinary Tract Infections Management
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Hemodynamic Monitoring and Therapy
- SARS-CoV-2 and COVID-19 Research
- Surgical site infection prevention
- Cancer, Lipids, and Metabolism
- Health Literacy and Information Accessibility
- Ferroptosis and cancer prognosis
- Streptococcal Infections and Treatments
- Ectopic Pregnancy Diagnosis and Management
- Social Media in Health Education
Children's Hospital of Chongqing Medical University
2024
Chongqing Medical University
2020-2024
University of Florida
2020-2024
Renji Hospital
2024
Florida College
2020-2024
Shanghai Jiao Tong University
2024
Lanzhou University
2024
Lanzhou University Second Hospital
2024
Zhejiang Energy Group (China)
2024
Third People's Hospital of Hefei
2024
The distribution of methicillin-resistant Staphylococcus aureus (MRSA) clones is dynamic and geographically unique. To understand the changing epidemiology MRSA infections in China, we performed a prospective, multicity surveillance study with molecular typing phenotypic analysis to determine association major prevalent their antimicrobial resistance profiles. A total 517 S. isolates collected between January 2009 March 2012 from six cities China were subjected antibiogram typing, including...
Thoracic surgery rapidly induces weakness in human diaphragm fibers. The dysfunction is thought to arise from combined effects of the surgical procedures and inactivity. This project tested whether brief bouts intraoperative hemidiaphragm stimulation would mitigate slow fast fiber loss force diaphragm. We reasoned that maintenance activity with phrenic myofilament protein derangements caused by thoracic surgery. Nineteen adults (9 females, age 59 ± 12 years) normal inspiratory strength or...
Background: Norepinephrine and phenylephrine are widely used for obstetric anesthesia. Our central objective was to determine the ED (effective dose) 90 potency ratio of prophylactic norepinephrine boluses preventing postspinal anesthesia hypotension during cesarean section. Methods: Patients scheduled elective section (n = 80) were randomly allocated receive (NE) or (PE) immediately after induction spinal An initial dose NE (3 μg) PE (37.5 given first patient, an up-and-down sequential...
Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary point, may be published when key planned co-primary or secondary analyses are not yet available. Trial Updates provide an opportunity to disseminate additional results from studies, in JCO elsewhere, for which point has already been reported. ARST1321 was a phase II study designed compare near complete pathologic response rate after preoperative...
Background The COVID-19 outbreak has increased challenges associated with health management, especially cancer management. In an effort to provide continuous pharmaceutical care patients, Sun Yat-sen University Cancer Center (SYSUCC) implemented a remote pharmacy service platform based on its already existing web-based hospital app known as Cloud SYSUCC. Objective aim of this study was investigate the characteristics, acceptance, and initial impact SYSUCC during in tertiary China. Methods...
In this article, we will discuss the genesis, evolution, and progress of INternational Soft Tissue SaRcoma ConsorTium (INSTRuCT), which aims to foster international research collaboration focused on pediatric soft tissue sarcoma. We begin by highlighting current state clinical for sarcomas, including rhabdomyosarcoma non-rhabdomyosarcoma then explore challenges priorities, describe development INSTRuCT, how consortium address key priorities.
Abstract Introduction The impact of established prognostic factors on survival outcomes for childhood rhabdomyosarcoma (RMS) have not been well described in the adolescent and young adult (AYA) RMS patient population. Methods This is a retrospective analysis patients with newly diagnosed enrolled between 1997 2016 seven previously reported Children's Oncology Group (COG) clinical trials. Demographics, features, treatment details, outcome data were collected. Five‐year event‐free (EFS)...
Abstract Background Embryonal sarcoma of the liver (ESL) is a rare mesenchymal tumor most common in childhood; optimal treatment approach uncertain. The clinical features and outcomes patients with ESL enrolled Children’s Oncology Group (COG) trial that evaluated risk‐based strategy for treating soft tissue sarcomas aged <30 years were evaluated. Methods This subset analysis included COG study ARST0332. Central review records, pathology, imaging confirmed diagnosis, presenting features,...
Background: Acute erythroid leukemia (AEL), also known as pure leukemia, is a rare subtype of acute myeloid (AML) characterized by the proliferation malignant precursors. Outcome data at population level are scarce. Methods: We performed retrospective analysis Surveillance Epidemiology and End Results (SEER) database. All cases with histologically confirmed diagnosis (pure) during period 2000–2019 were included in study. The Kaplan–Meier method was used to perform survival analysis....
Abstract Background Novel therapies are needed for relapsed and refractory rhabdomyosarcoma (RRMS). Phase II clinical trials in RRMS have typically utilized radiologic response as the primary activity endpoint, an approach that poses several limitations RRMS. In this analysis, we aimed to estimate event‐free survival (EFS) endpoint could be used a benchmark future studies. Procedure We performed retrospective study of patients with enrolling on 13 single‐agent phase Children's Oncology Group...
Establishing prediction models of pregnancy outcomes for recurrent loss women at specific gestational weeks will provide patients and physicians with more precise information, ultimately leading to time cost savings associated unnecessary revisits. Therefore, our aim was develop a model first trimester in RPL patients. We used ultrasound indices during the combination demographic characteristics commonly serum markers. The independent risk factors each week were as follows: age P fifth week;...
Abstract Study Objective Prophylactic norepinephrine infusion effectively lowers the incidence of postspinal anesthesia hypotension. The optimal prophylactic dose remains undefined. purpose this study was to investigate prevent hypotension in patients undergoing cesarean section. Design Prospective, double‐blind, randomized, controlled, dose‐finding trial. Setting Operating room from March 2020 June 2020. Patients Ninety nine primipara or multipara women 18 ‐ 40 years age, singleton...
Abstract Background Temsirolimus has shown in vivo activity against rhabdomyosarcoma (RMS). We aimed to determine the feasibility of incorporating temsirolimus within standard Children's Oncology Group (COG) chemotherapy backbone vincristine, actinomycin‐D, and cyclophosphamide (VAC) alternating with vincristine irinotecan (VI) children intermediate‐risk (IR) RMS. Methods The phase COG IR‐RMS trial, ARST1431 (NCT02567435), assigned 10 patients receive 15 mg/m 2 /dose (dose level 1) on days...
Biliary rhabdomyosarcoma (RMS) is the most common biliary tumor in children. The tract classified as a favorable primary site. Therefore, patients with localized RMS were included two consecutive low-risk studies, D9602 and ARST0331, by Children's Oncology Group (COG). outcome for these treated therapy has not been reported.
Abstract Background Orbital rhabdomyosarcoma (ORMS) commonly presents as low‐risk disease (stage 1, group I–III, embryonal RMS) with excellent outcome. Long‐term follow‐up of patients ORMS and outcomes less common subgroups treated on recent Children's Oncology Group (COG) trials have not been reported. Methods Patients enrolled COG from 1997 to 2013 were identified. Demographic information characteristics collected. Outcomes determined for the following subgroups: 1) ORMS, 2) resected...