A5101609871- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Occupational exposure and asthma
- Parasitic Diseases Research and Treatment
- RNA modifications and cancer
- Fungal Infections and Studies
- Occupational and environmental lung diseases
- Ubiquitin and proteasome pathways
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Antifungal resistance and susceptibility
- Pulmonary Hypertension Research and Treatments
- Genetics and Neurodevelopmental Disorders
- Peptidase Inhibition and Analysis
Soochow University
2022-2025
First Affiliated Hospital of Soochow University
2025
First Affiliated Hospital of Jiangxi Medical College
2025
Jiangxi Provincial People's Hospital
2020-2025
The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
2022
Nanchang University
2020
Identifying the common functional single-nucleotide polymorphisms (SNPs) that can both affect susceptibility to idiopathic pulmonary fibrosis (IPF) and silicosis. We first integrated genome-wide association studies (GWASs) of IPF silicosis obtain shared SNPs. Following this, expression quantitative trait locus (eQTL)-SNPs were identified by GTEx database. This was followed validation correlation between these eQTL-SNPs through an additional case-control study including 194 cases 235 healthy...
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive malignancy characterized by limited prognostic markers treatment options, contributing to high mortality rates. While Ubiquitin‐specific peptidase 5 (USP5) has been implicated in various cancers, its role HNSCC remains poorly understood. Aims This study aims investigate the of USP5 progression explore potential as both biomarker therapeutic target. Materials & Methods work utilized single‐cell...
Hypoxia plays a crucial role in pulmonary vascular remodelling at the early stage of chronic obstructive disease (COPD). Circle RNA (circRNA) has been identified to play critical multiple diseases. However, circRNAs COPD remains unclear. In this study, we aim investigate arterial smooth muscle cell proliferation and COPD. patients show lower partial pressure oxygen remodeling as compared with controls. circRNA microarray real-time PCR analyses significantly higher level circ-BPTF miR-486-5p...
Oral squamous cell carcinoma (OSCC) is a lethal malignancy. It reportedly demonstrated that long non-coding RNA (lncRNA) participates in the development of OSCC. The purpose this study was to clarify function and possible molecular mechanisms lncRNA MCM3AP antisense 1 (lncRNA MCM3AP-AS1) Quantitative real-time PCR (qRT-PCR) adopted investigate MCM3AP-AS1 expressions OSCC tissues cells. proliferation, migration invasion HN-6 SCC-9 cells were probed by counting kit-8 Transwell assays,...