Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by socio-communicative impairments. Executive dysfunction may explain some key characteristics of ASD, both social and nonsocial hallmarks. Limited research exists exploring the relations between executive function impairment in ASD few studies have used comparison control group. Thus, objective present study was to investigate functioning using Behavioral Rating Inventory Functioning (BRIEF), as measured Social...

Autism Spectrum Disorder (ASD) is a clinically diagnosed, heterogeneous, neurodevelopmental condition, whose underlying causes have yet to be fully determined. A variety of studies investigated either cortical, subcortical, or cerebellar anatomy in ASD, but none conducted complete examination all neuroanatomical parameters on single, large cohort. The current study provides comprehensive brain development children with ASD between the ages 4 and 18 years who are carefully matched for age sex...

Abstract Introduction This study is the first to characterize normal development and sex differences across neuroanatomical structures in cortical, subcortical, cerebellar brain regions a single large cohort. Methods One hundred ninety‐two magnetic resonance images were examined from 96 typically developing females age‐matched males 4 18 years of age. Image segmentation cortex was conducted with CIVET , while that cerebellum, hippocampi, thalamus, basal ganglia using MAGeT algorithm. Results...

Autism spectrum disorder (ASD) is increasingly understood to be associated with aberrant functional brain connectivity.Few studies, however, have described such atypical neural synchrony among specific regions.Here, we used magnetoencephalography (MEG) characterize alterations in connectivity adolescents ASD through source space analysis of phase synchrony.Resting-state MEG data were collected from 16 and 15 age-and sex-matched typically developing (TD) adolescents.Atlas-guided...

Autism spectrum disorder (ASD) is a neurodevelopmental characterized by impairments in social cognition. The biological basis of deficits cognition ASD, and their difficulty processing emotional face information particular, remains unclear. Atypical communication within between brain regions has been reported ASD. Interregional phase-locking neurophysiological mechanism mediating among areas understood to support cognitive functions. In the present study we investigated interregional...

Executive functioning (EF) deficits are well-documented in Autism Spectrum Disorder (ASD), yet little is known about the longitudinal trajectory of 'everyday' EF and links to social, emotional behavioural outcomes ASD. This study examined profile everyday utilizing parent-reported measures over 2 years, explored whether prior estimates were related later co-morbid psychopathology social 39 children with ASD 34 typically developing (TD) (ages 7-14 years). According parent reports, had...

Impaired social interaction is one of the hallmarks Autism Spectrum Disorder (ASD). Emotional faces are arguably most critical visual stimuli and ability to perceive, recognize, interpret emotions central communication, subsequently healthy development. However, our understanding neural cognitive mechanisms underlying emotional face processing in adolescents with ASD limited. We recruited 48 adolescents, 24 high functioning typically developing controls. Participants completed an implicit...

Individuals with autism spectrum disorder (ASD) demonstrate poor social functioning, which may be related to atypical emotional face processing. Altered functional connectivity among brain regions, particularly involving limbic structures implicated. The current magnetoencephalography (MEG) study investigated whole-brain of eight a priori identified regions during the implicit presentation happy and angry faces in 20 7–10-year-old children ASD 22 typically developing controls. Findings...

Social cognition is impaired in Autism Spectrum Disorder (ASD). The ability to perceive and interpret affect integral successful social functioning has an extended developmental course. However, the neural mechanisms underlying emotional face processing ASD are unclear. Using magnetoencephalography, present study explored activation during implicit young adults with without ASD. Twenty-six 26 healthy controls were recruited. Participants indicated location of a scrambled pattern (target)...

There is gathering consensus that altered connectivity a hallmark of the autistic brain. This includes atypical neural oscillations and their coordination across brain regions, which are understood to mediate information processing integration. It remains unclear whether how in various neurophysiological frequency ranges develops atypically autism spectrum disorder (ASD).To address this cross-sectional sample, we recorded resting-state magnetoencephalography from 134 children adolescents...

Socio-emotional difficulties in autism spectrum disorder (ASD) are thought to reflect impaired functional connectivity within the "social brain". Nonetheless, a whole-brain characterization of fast responses during implicit processing emotional faces adults with ASD is lacking. The present study used magnetoencephalography investigate early connectivity, as measured by interregional phase synchronization, angry, neutral and happy faces. sample (n = 44) consisted 22 young age- sex-matched...

Abstract Autism spectrum disorder (ASD) is characterized by social deficits and atypical facial processing of emotional expressions. The underlying neuropathology these abnormalities still unclear. Recent studies implicate cerebellum in processing; other show cerebellar ASD. Here, we elucidate the spatiotemporal activation lobules ASD during happy angry faces adolescents with typically developing (TD) controls. Using magnetoencephalography, calculated dynamic statistical parametric maps...

Standardized protocols have been shown to reduce clinical practice variation and improve patient outcomes.To measure the impact of a standardized nutrition bundle inclusive donor human milk (DHM) on hospital outcomes very low birth-weight (VLBW) infants in safety-net hospital.The study used Model for Improvement methodology drive improvement practice. Outcome measures consisted necrotizing enterocolitis (NEC), mortality, growth at 36 weeks' postmenstrual age discharge, as well volume type...

Working memory impairment is associated with symptom severity and poor functional outcome in autistic individuals, yet the neurobiology underlying such deficits poorly understood. Neural oscillations are an area of investigation that can shed light on this issue. Theta alpha have been found consistently to support working typically developing individuals also shown be functionally altered people autism. While there evidence, largely from magnetic resonance imaging studies, neural processing...