A5033323648- RNA Interference and Gene Delivery
- Computational Drug Discovery Methods
- RNA and protein synthesis mechanisms
- SARS-CoV-2 and COVID-19 Research
- Virology and Viral Diseases
- vaccines and immunoinformatics approaches
- Yersinia bacterium, plague, ectoparasites research
- Bacillus and Francisella bacterial research
- Mosquito-borne diseases and control
- Protein Hydrolysis and Bioactive Peptides
- MicroRNA in disease regulation
- Trypanosoma species research and implications
- Vibrio bacteria research studies
- Plant Molecular Biology Research
- Viral Infections and Outbreaks Research
- Protein Structure and Dynamics
- Synthesis and Biological Evaluation
- Viral gastroenteritis research and epidemiology
- HIV/AIDS drug development and treatment
- Microbial Natural Products and Biosynthesis
- Research on Leishmaniasis Studies
- RNA Research and Splicing
- GABA and Rice Research
- HIV Research and Treatment
- Antimicrobial Resistance in Staphylococcus
University of Chittagong
2012-2016
Malaria has been a major life threatening mosquito borne disease from long since. Unavailability of any effective vaccine and recent emergence multi drug resistant strains malaria pathogen Plasmodium falciparum continues to cause persistent deaths in the tropical sub-tropical region. As result, demands for new targets more anti-malarial drugs are escalating. Transketolase is an enzyme pentose phosphate pathway; novel pathway which involved energy generation nucleic acid synthesis. Moreover,...
In developing countries threat of cholera is a significant health concern whenever water purification and sewage disposal systems are inadequate. Vibrio cholerae one the responsible bacteria involved in disease. The complete genome sequence V. deciphers presence various genes hypothetical proteins whose function not yet understood. Hence analyzing annotating structure important for understanding cholerae. O139 most common pathogenic bacterial strain among strains. this study six has been...
The Middle East respiratory syndrome coronavirus (MERS-CoV) is a virus that manifests itself in viral infection with fever, cough, shortness of breath, renal failure and severe acute pneumonia, which often result fatal outcome. MERS-CoV has been shown to spread between people who are close contact. Transmission from infected patients healthcare personnel also observed irredeemable present technology. Genetic studies on have ORF1ab encodes replicase polyproteins play foremost role infection....
Ebola virus (EBOV) is such kind of which responsible for 23,825 cases and 9675 deaths worldwide only in 2014 with an average diseases fatality rate between 25 % 90 %. Although, medical technology has tried to handle the problems, there no Food Drug Administration (FDA)-approved therapeutics or vaccines available prevention, post exposure, treatment disease (EVD).In present study, we used immunoinformatics approach design a potential epitope-based vaccine against RNA-dependent RNA...
Plague is a major health concern and Yersinia pestis plays the central causal role in this disease.Yersinia has developed resistance against commonly available drugs.So, it now key to find new drug target.Cysteine protease YopT enzyme an important factor used by for pathogenesis its host antiphagocytic function of removal Ctermini lipid modification.The 3D structure cysteine was determined means homology modeling through multiple alignments followed intensive optimization validation.The done...
Background: The herpes simplex virus (HSV-1) is a that manifests itself in viral infection with painful, watery blisters the skin or on genitals as well mucous membrane such mouth lips.During an outbreak, disease contagious particularly and irredeemable present technology.Genetic studies of HSV-1 have shown ICP22 (US1) gene immediate early responsible for genome replication also has contribution infection.Method: For diagnosis, may be suitable target.Viral activity can controlled through RNA...
A commonly diagnosed cancer, prostate cancer (PrCa), is being regulated by the gene RNASEL previously known as PRCA1 codes for ribonuclease L which an integral part of interferon system that mediates antiviral and antiproliferative role interferons. Both somatic germline mutations have been implicated to cause cancer. With array available Single Nucleotide Polymorphism data on dbSNP this study designed sort out functional SNPs in implementing different authentic computational tools such...
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The Middle East respiratory syndrome coronavirus (MERS-CoV) is a virus that manifests itself in viral infection with fever, cough, shortness of breath, renal failure and severe acute pneumonia, which often result fatal outcome. MERS-CoV has been shown to spread between people who are close contact. Transmission from infected patients healthcare personnel also observed irredeemable present technology. Genetic studies on have ORF 1ab encodes replicase polyproteins play foremost role infection....
The issue of balanced nutrition is great concern to human.Meat and fish are the best sources protein.The affordability these resources for people in developing countries less.Thus, there an increasing interest pulses its derivates as alternative meat.Lectin histone H1 most common proteins various our identifying dominant essential amino acids them use supplements.However, actin lectin among Oryza Sativa cicer arietinum.We describe amount arietinum, Lens culinaris Pisum sativum a comparative...