A5007558540- Sleep and related disorders
- Sleep and Wakefulness Research
- Sleep and Work-Related Fatigue
- Circadian rhythm and melatonin
- Exercise and Physiological Responses
- EEG and Brain-Computer Interfaces
- Sports Performance and Training
- Heart Rate Variability and Autonomic Control
- Adipose Tissue and Metabolism
- Thermoregulation and physiological responses
- High Altitude and Hypoxia
- Neurotransmitter Receptor Influence on Behavior
- Muscle metabolism and nutrition
- Cardiovascular and exercise physiology
- Stress Responses and Cortisol
- Occupational Health and Performance
- Regulation of Appetite and Obesity
- Obstructive Sleep Apnea Research
- Adipokines, Inflammation, and Metabolic Diseases
- Obesity, Physical Activity, Diet
- Health and Lifestyle Studies
- Neuroscience and Neuropharmacology Research
- Dietary Effects on Health
- Spaceflight effects on biology
- Coffee research and impacts
Université Paris Cité
2016-2025
Institut thématique Santé Publique
2022-2025
Sorbonne Paris Cité
2015-2024
Hôtel-Dieu de Paris
2013-2024
Biomedical Research Institute
2016-2024
Service de Santé des Armées
2009-2023
Sommeil, vigilance, fatigue et santé publique
2023
Armed Forces Institute of Pathology
2023
Assistance Publique – Hôpitaux de Paris
2013-2022
Santé Publique France
2022
Abstract Study Objectives The development of ambulatory technologies capable monitoring brain activity during sleep longitudinally is critical for advancing science. aim this study was to assess the signal acquisition and performance automatic staging algorithms a reduced-montage dry-electroencephalographic (EEG) device (Dreem headband, DH) compared gold-standard polysomnography (PSG) scored by five experts. Methods A total 25 subjects who completed an overnight at center while wearing both...
Sleep disorders are associated with inflammation and sympathetic activation, which suspected to induce endothelial dysfunction, a key factor in the increased risk of cardiovascular disease. Less is known about early effects acute sleep deprivation on vascular function. We evaluated microvascular reactivity biological markers activation during continuous 40 h total (TSD) 12 healthy men (29 +/- 3 yr). The days before [day 1 (D1)] TSD (D3), at 1200 1800, endothelium-dependent -independent...
Summary The link between sleepiness and the risk of motor vehicle accidents is well known, but little understood regarding home, work car subjects with insomnia. An international cross‐sectional survey was conducted across 10 countries in a population sleep disturbances. Primary care physicians administered questionnaire that included assessment sociodemographic characteristics, disturbance (motor vehicle, home) related to problems each subject. Insomnia defined using International...
The Ramadan fasting (RF) period is associated with changes in sleep habits and increased sleepiness, which may affect physical performance athletes, induce metabolic, hormonal, inflammatory disturbances. In 8 middle-distance athletes (25.0 ± 1.3 years), a maximal aerobic velocity (MAV) test was performed 5 days before RF (day –5), on 7 21 of RF. same days, saliva samples were collected to determine cortisol testosterone concentrations after the MAV test. Blood (P1), at end (P2), 1 week post...
Objectives:To investigate the effects of 6 nights sleep extension on sustained attention and pressure before during total deprivation after a subsequent recovery sleep.
Here, we studied muscle-specific and muscle-related miRNAs in plasma of exercising humans. Our aim was to determine whether they are affected by eccentric and/or concentric exercise modes could be biomarkers muscle injuries or possible signaling molecules. On two separate days, nine healthy subjects randomly performed 30-min walking exercises, one downhill (high component) uphill component). Perceived exertion heart rate were higher during the exercise, while subjective pain ankle plantar...
Recent research has shown that auditory closed-loop stimulation can enhance sleep slow oscillations (SO) to improve N3 quality and cognition. Previous studies have been conducted in lab environments. The present study aimed validate assess the performance of a novel ambulatory wireless dry-EEG device (WDD), for SO during at home. WDD detect automatically send on were tested 20 young healthy subjects who slept with both miniaturized polysomnography (part 1) stimulated sham nights within...
Sleepiness and fatigue can reach particularly high levels during long-haul overnight flights. Under these conditions, voluntary or even involuntary sleep periods may occur, increasing the risk of accidents. The aim this study was to assess performance an in-flight automatic detection system low-vigilance states using a single electroencephalogram channel. Fourteen healthy pilots voluntarily wore miniaturized brain electrical activity recording device flights ( 10 ±2.0 h, Atlantic 2 Falcon 50...
The aim of this study was to evaluate stress markers, mood states and sleep indicators in high-level swimmers during a major 7-days competition according the outcomes. Nine (6 men 3 women (age: 22 ± 2 years 4 years, respectively) were examined. Before (PRE) after (POST) each race (series, semi-finals finals), salivary concentrations cortisol, α-amylase (sAA) chromogranin-A (CgA) determined. Mood assessed by profile state (POMS) questionnaire completed before 7-days, self-reported diaries...
Professional burnout syndrome has been described in association with insomnia and metabolic, inflammatory immune correlates. We investigated the interest of exploring biological parameters sleep disturbances relation to symptoms among white-collar workers. Fifty-four participants were compared 86 healthy control terms professional rank level, sleep, job strain (Karasek questionnaire), social support, anxiety depression (HAD scale). Fasting concentrations glycaemia, glycosylated hemoglobin...
Physical exercise induces neuroprotection through anti-inflammatory effects and total sleep deprivation is reported an inflammatory process. We examined whether 7 weeks of training attenuates markers inflammation during (24-h wakefulness) in the rat brain periphery. Four groups 10 rats were investigated: Sedentary control, sleep-deprived, Exercised sleep-deprived. Sleep induced using slowly rotating wheels a motorized treadmill. mRNA expression pro-inflammatory (IL-1β, TNF-α, IL-6)...
Study Objective To investigate pain sensitivity after sleep restriction and the restorative effect of napping. Design A strictly controlled randomized crossover study with continuous polysomnography monitoring was performed. Setting Laboratory-based study. Participants 11 healthy male volunteers. Interventions Volunteers attended two three-day sessions: “sleep restriction” alone nap”. Each session involved a baseline night normal sleep, deprivation free recovery sleep. were allowed to only...
Objectives Professional burnout is closely related to work stress but less frequently associated with disturbed sleep. This study determines whether job strain and sleep disturbances are risk factors of among financial workers. Design Observational study. Participants 1300 employees (725 female) a company. Primary measures Self-reported questionnaires (Maslach Burnout Inventory, Job Content Questionnaire, Sleep questionnaire based on ICSD-3 classification), the Epworth sleepiness scale...
<i>Objectives:</i> This study was designed to determine immune and hormonal changes their relationship with the incidence of upper respiratory tract infections (URTIs) during an extremely stressful military training (3 weeks physical conditioning followed by a 5-day combat course energy restriction, sleep deprivation psychological stress). <i>Methods:</i> Blood samples were collected from 21 cadets (21 ± 2 years old) before after for analysis leukocyte lymphocyte...
This study was designed to determine whether serum leptin levels were affected by a 5-d military course after 3 wk of combat training.26 male soldiers (mean age = 21 +/- 2 yr) examined at the beginning training program and just end course. The combination continuous heavy physical activity sleep deprivation led energy deficiency. Blood samples analyzed for leptin, insulin, cortisol, adrenocorticotropin (ACTH), testosterone; plasma free fatty acids (FFA), glycerol, glucose, catecholamines.At...