A5057105317- Photochemistry and Electron Transfer Studies
- Antimicrobial Peptides and Activities
- Spectroscopy and Quantum Chemical Studies
- Algal biology and biofuel production
- Metabolomics and Mass Spectrometry Studies
- Lipid metabolism and biosynthesis
- Photosynthetic Processes and Mechanisms
- Alkaline Phosphatase Research Studies
- Photoreceptor and optogenetics research
- Cardiac Health and Mental Health
- Calcium signaling and nucleotide metabolism
- Biochemical and Structural Characterization
- Spine and Intervertebral Disc Pathology
- Cell death mechanisms and regulation
- Pesticide and Herbicide Environmental Studies
- Toxoplasma gondii Research Studies
- bioluminescence and chemiluminescence research
- Cellular transport and secretion
- Ferroptosis and cancer prognosis
- Plant Micronutrient Interactions and Effects
- Peroxisome Proliferator-Activated Receptors
- Invertebrate Immune Response Mechanisms
- Polydiacetylene-based materials and applications
- Plant Stress Responses and Tolerance
- DNA and Nucleic Acid Chemistry
La Trobe University
2019-2024
Research Triangle Park Foundation
1995
Montana State University
1987-1991
United States Department of Veterans Affairs
1989
Purdue University West Lafayette
1985
The glycoprotein (GP) Ib-IX complex on the surface of human platelets functions as von Willebrand factor receptor and mediates factor-dependent platelet adhesion to blood vessels. GPIX is a relatively small (Mr, 17,000) protein that may provide for membrane insertion orientation larger component complex, GPIb 165,000). Using antibody screening, we cloned cDNA encoding from erythroleukemia cell library constructed in phage lambda gt11. Lacking 5' untranslated region start codon, sequence...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFluorescence Lifetime Measurements of Fluoranthene, 1-Naphthol, and Napropamide in the Presence Dissolved Humic AcidShaojin. Chen, William P. Inskeep, Scott A. Williams, Patrik R. CallisCite this: Environ. Sci. Technol. 1994, 28, 9, 1582–1588Publication Date (Print):September 1, 1994Publication History Published online1 May 2002Published inissue 1 September...
Defensins form an integral part of the cationic host defence peptide (HDP) family, a key component innate immunity. Apart from their antimicrobial and immunomodulatory activities, many HDPs exert multifaceted effects on tumour cells, notably direct oncolysis and/or inhibition cell migration. Therefore, have been explored as promising anticancer therapeutics. Human β-defensin 2 (HBD-2) represents prominent member human HDPs, being well-characterised for its potent pathogen-killing,...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure-function relationships in the 47-kDa antenna protein and its complex with photosystem II reaction center core: insights from picosecond fluorescence decay kinetics resonance Raman spectroscopyJulio C. de Paula, Ann Liefshitz, Sarina Hinsley, Wei Lin, Vikas Chopra, Kathryn Long, Scott A. Williams, Betts, Charles F. YocumCite this: Biochemistry 1994, 33, 6, 1455–1466Publication Date (Print):February 15, 1994Publication History Published...
Here, we describe GS-9, a novel water-soluble fatty acid-based formulation comprising L-lysine and arachidonic acid, that have shown to induce ferroptosis. GS-9 forms vesicle-like structures in solution mediates lipid peroxidation, as evidenced by increased C11-BODIPY fluorescence an accumulation of toxic malondialdehyde, downstream product peroxidation. Ferroptosis inhibitors counteracted GS-9-induced cell death, whereas caspase 3 7 or MLKL knock-out lines are resistant eliminating other...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPolarized fluorescence of thymine in neutral aqueous solution at room temperature: evidence for interference from the anion and .pi..pi.* nature fluorescenceScott A. Williams, Curtiss N. Renn, Patrik R. CallisCite this: J. Phys. Chem. 1987, 91, 11, 2730–2734Publication Date (Print):May 1, 1987Publication History Published online1 May 2002Published inissue 1...
Undecylenic acid, a monounsaturated fatty is currently in clinical use as topical antifungal agent, however the potential for therapeutic application other disease settings has not been investigated. In this study, we describe novel platform solubilization of acids using amino and utilize approach to define tumoricidal activity underlying mechanism undecylenic acid. We examined formulation acid compounded with L-Arginine, called GS-1, that induced concentration-dependent tumor cell death,...
Abstract Crocodilians are an order of ancient reptiles that thrive in pathogen-rich environments. The ability to inhabit these harsh environments is indicative a resilient innate immune system. Defensins, family cysteine-rich cationic host defence peptides, major component the systems all plant and animal species, however crocodilian defensins poorly characterised. We now show saltwater crocodile defensin CpoBD13 harbors potent antifungal activity mediated by pH-dependent membrane-targeting...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLocalization of Excitations by Electron-Donating Side Groups in the Novel Copolymer Poly[methylphenyl-co-methyl-4-(dimethylamino)phenylsilane]D. A. M. Smith, S. Williams, P. Jenkner, R. D. Miller, E. J. Ginsburg, and HochstrasserCite this: Phys. Chem. 1994, 98, 30, 7359–7365Publication Date (Print):July 1, 1994Publication History Published online1 May 2002Published inissue 1 July...
Polarized two-photon fluorescence excitation spectra were obtained for the nucleotides TMP, CMP, GMP, and AMP in neutral aqueous room temperature solution (0.05M). The wavelength range was 400- 600 nm, corresponding to states reached with 200-300 nm single UV photons. INDO/S-CI predictions carried out methyl bases, somewhat useful 260 bands certain parameterizations. Theory failed find strong absorption seen below 450 which may be of Rydberg origin.
Crocodilians are an order of ancient reptiles that thrive in pathogen-rich environments.The ability to inhabit these harsh environments is indicative a resilient innate immune system.Defensins, family cysteine-rich cationic host defence peptides, major component the systems all plant and animal species, however crocodilian defensins poorly characterised.We now show saltwater crocodile defensin CpoBD13 harbors potent antifungal activity mediated by novel pH-dependent membrane-targeting...
Journal Article Freedom under Seige: The Impact of Organized Religion on Your Liberty and Pocketbook. By Madalyn Murray O'Hair. Los Angeles: J. P. Tarcher, Inc., 1974. 278 pp. $8.95 Get access Sidney Algernon Williams Search for other works by this author on: Oxford Academic Google Scholar Church State, Volume 21, Issue 2, Spring 1979, Pages 365–366, https://doi.org/10.1093/jcs/21.2.365 Published: 01 March 1979