Junlong Sun

ORCID: 0000-0002-4482-2925
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About
Contact & Profiles
Research Areas
  • Physiological and biochemical adaptations
  • Aquaculture Nutrition and Growth
  • Aquaculture disease management and microbiota
  • Selenium in Biological Systems
  • MicroRNA in disease regulation
  • Cancer, Hypoxia, and Metabolism
  • melanin and skin pigmentation
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Circular RNAs in diseases
  • interferon and immune responses
  • Cancer-related molecular mechanisms research
  • Marine Bivalve and Aquaculture Studies
  • Biochemical Analysis and Sensing Techniques
  • Adipose Tissue and Metabolism
  • Zebrafish Biomedical Research Applications
  • Plant Molecular Biology Research
  • Fish Ecology and Management Studies
  • Rock Mechanics and Modeling
  • Fern and Epiphyte Biology
  • Heat shock proteins research
  • Landslides and related hazards
  • Reproductive biology and impacts on aquatic species
  • Olfactory and Sensory Function Studies
  • Invertebrate Immune Response Mechanisms
  • Biofuel production and bioconversion

Hainan University
2021-2025

Sir Run Run Shaw Hospital
2024-2025

Zhejiang University
2024-2025

Qinghai University
2025

Ministry of Agriculture and Rural Affairs
2025

Huadong Hospital
2025

Fudan University
2025

Wenzhou Central Hospital
2024

Huzhou Central Hospital
2024

Zhejiang Chinese Medical University
2024

Staphylococcus aureus (S. aureus) internalization into bovine mammary epithelial cells (bMECs) is considered an important pathogenic mechanism for the establishment of mastitis. Given interesting link between selenium (Se) status and mastitis, our objective was to prove that Se essential suppress pro-inflammatory mediators, in part, by modulation Toll-like receptor2 (TLR2), nuclear factor kappaB (NF-κB) mitogen activated protein kinase (MAPK) signal transduction pathway bMECs.Results showed...

10.1186/s12917-018-1508-y article EN cc-by BMC Veterinary Research 2018-06-20

Abstract Accumulating studies have investigated the efficacy of receptor‐mediated delivery hydrophobic drugs in glioma chemotherapy. Here, a vehicle comprising polyethylene glycol (PEG) and oxidized nanocrystalline mesoporous carbon particles (OMCN) linked to Pep22 polypeptide targeting low‐density lipoprotein receptor (LDLR) is designed generate novel drug‐loaded system, designated as OMCN–PEG–Pep22/DOX (OPPD). This system effectively targets cells blood–brain barrier exerts therapeutic...

10.1002/smll.201801905 article EN Small 2018-09-14

The pacific white shrimp (Litopenaeus vannamei) is now a more common aquaculture species in saline-alkali waters, while alkalinity stress considered to be one of the stressors for shrimp. Thus, an understanding molecular response critical advancing sustainability culture In this study, we aimed explore mechanism acute high-alkaline by RNA-seq at low-alkaline (50 mg/L) and (350 mg/L). We identified 215 differentially expressed mRNAs (DEGs) 35 miRNAs (DEMs), which 180 DEGs 28 DEMs were...

10.1371/journal.pone.0290157 article EN cc-by PLoS ONE 2023-08-17

Abstract Antimicrobial proteins contribute to host-microbiota interactions and are associated with inflammatory bowel disease (IBD), but our understanding on antimicrobial protein diversity functions remains incomplete. Ribonuclease 4 (Rnase4) is a potential no known function in the intestines. Here we find that RNASE4 expressed intestinal epithelial cells (IEC) including Paneth goblet cells, detectable human mouse stool. Results from Rnase4- deficient mice recombinant suggest Rnase4 kills...

10.1038/s41467-024-50223-1 article EN cc-by Nature Communications 2024-07-10

Because of the continuous intensification global warming, extreme climate fluctuations, and high-density farming, cold-water rainbow trout (Oncorhynchus mykiss) are exposed to conditions heat stress, which has severely impacted their survival yield. Nano-selenium (nano-Se) shows higher biological activity lower toxicity emerged as an ideal ecological Se formulation. Herein were fed either a basal diet (control group) or plus 5 mg/kg nano-Se (treatment group). Samples collected before (18 °C...

10.1016/j.ecoenv.2022.113736 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2022-06-08
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